Antioxidant activity of brown macroalgae Sargassum ethanol extract from Lombok coast, Indonesia

Abstract

The coastal areas of Lombok has very high diversity of macroalgae which are largely unexplored. Among them are the brown macroalgae Sargassum species which are well known for their biological potentials. In this study, we aim to evaluate 4 Sargassum species, S.cristaefolium, S. crassifolium, S. polycystum, and S. aquifolium for their antioxidant potential of Sargassum species found the west coastal Aare of Lombok, Indonesia. To determine the antioxidant capacity of macroalgal extracts, 2,2-diphenyl-1-picrylhydrazyl (DPPH) as well as total phenolic content (TPC) were measured. Extracts of the brown macroalgae are well known to have very active antioxidant activity. Among them S. cristaefolium and S.crassifolium provide stronger antioxidant activity compared to S.aquifolium and S.polycystum. Furthermore, correlations were found between TPC macroalgal and their DPPH scavenging activity. This indicates an important role of polyphenols as antioxidants. Overall, brown macroalgae from Lombok coastal area may be a good source of natural bioactive compounds.

Effect of particle size on phytochemical composition and antioxidant properties of Sargassum cristaefolium ethanol extract

“…Brown macroalgae are well known to be rich in polyphenol compounds which potentially contribute to its antioxidant capacity 7 . The brown seaweed Sargassum species have shown strong antioxidant activity 8 . The brown macroalgae Sargassum cristaefolium is one of the most abundant Sargassum species in the coastal area of Lombok, Indonesia.…”

Exploring Bioactive Components and Assessing Antioxidant and Antibacterial Activities in Five Seaweed Extracts from the Northeastern Coast of Algeria

“…These inhibition concentrations are better than those obtained for D. dichotoma (IC 50 = 458.24 ± 2.98 µg·mL −1 ), found in the Gulf of Mannar, between southeast India and eastern Sri Lanka [ 74 ]. The highest effective concentration ever observed was even found in the study by Prasedya et al [ 75 ] for several species of Sargassum sp. (IC 50 = 737.30 ± 23.46 g·mL −1 ).…”

Applications of Antioxidant Secondary Metabolites of Sargassum spp.

“…Clearly, phenolic compounds, in particular phlorotannins, appear as the major and most well studied group of compounds contributing to the antioxidant properties of Sargassum seaweeds. Indeed, positive correlations between phenolic content and antioxidant activity have been reported in many studies using whole algae, their parts, extracts, or fractions [ 74 , 75 , 76 , 77 ]. Notably, studies on phlorotannins isolated from Sargassum have shown that compounds, such as triphlorethol B, tetraphlorethol C, and pentaphlorethol A, can be more effective than certain antioxidant references such as ascorbic acid or resveratrol at preventing lipid peroxidation or scavenging of O 2 •− radicals [ 78 ].…”