Antioxidant activity of blueberry fruit is impaired by association with milk

Serafini, Mauro; Testa, Maria Francesca; Villaño, Débora; Pecorari, Monia; Wieren, Karin van; Azzini, Elena; Brambilla, Ada; Maiani, Giuseppe

doi:10.1016/j.freeradbiomed.2008.11.023

Cited by 105 publications

(81 citation statements)

References 45 publications

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“…An example is the case of fruits with milk, which is contraindicated. This concept is recently validated by a study conducted on milk and blue berries where it is demonstrated that, when used together, it leads 23 to reduction in the antioxidant properties of blueberries. Like this, eighteen types of virudha have been mentioned, when consumed for a prolonged time leads to various metabolic as well as other systemic diseases.…”

Section: Selection Of Food Based On Samskaramentioning

confidence: 92%

Ayurvedic Dietary Principles in Prevention and Management of Diabetes: A Review

Edavalath¹

2018

Endocrinol Diabetes Obes

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Diabetes mellitus, especially Type-2 is one of the major non-communicable diseases with growing prevalence at the global level. Major contributory factors for diabetes are genetic predisposition, environmental factors, lifestyle and unhealthy diet. Poorly controlled diabetes can lead to a number of complications and food can be a powerful tool in preventing or reversing diabetes. Modern dietetics adopt a reductionist view in determining the diet protocol with emphasis on the macro as well as micronutrients in the food and overlooks the varied demands of the person consuming it. This is where India's traditional medical system, Ayurveda can contribute with its holistic approach. Ayurveda advocates diet that is tailored to meet the needs of the individual. The dietary guidelines incorporate multiple factors comprising the prakriti (body composition), dosha (body humors),agni (digestive power), desa (place of living), kãla (age and season) and sathmya (homogeneity) of the individual. Following such a diet pattern in the long run will aid in preventing metabolic diseases, especially diabetes. In case of manifested diabetes, the management protocol is formulated based on the above said factors and consequently the diet also should be personalized. Differences in the metabolic demands among patients who are obese and non-obese warrants separate dietary guidelines for both groups. Hence a relook into the basics of ayurvedic dietetics and therapeutic approaches could enable researchers and practitioners to have fresh insights in the prevention and management of diabetes mellitus.

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Section: Selection Of Food Based On Samskaramentioning

confidence: 92%

Ayurvedic Dietary Principles in Prevention and Management of Diabetes: A Review

Edavalath¹

2018

Endocrinol Diabetes Obes

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“…The overall 0-24 h excretion of phenolic acids was 62 mmol after drinking orange juice alone and this fell markedly to 9·3 mmol when the orange juice was ingested with yoghurt (161) . There were also several other studies that showed that the absorption of phenolic compounds or increased plasma antioxidant capacity is suppressed when the compounds are consumed with milk (162,163) . Most studies have attributed this inhibitory effect of milk to milk proteins because phenolic compounds can bind to milk proteins through hydrogen bonds and hydrophobic interactions (124,164) .…”

Section: Interaction Of Plant Phenols With Proteinsmentioning

confidence: 99%

Interaction of plant phenols with food macronutrients: characterisation and nutritional–physiological consequences

Zhang

Sun

et al. 2013

Nutr. Res. Rev.

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Polyphenols are dietary constituents of plants associated with health-promoting effects. In the human diet, polyphenols are generally consumed in foods along with macronutrients. Because the health benefits of polyphenols are critically determined by their bioavailability, the effect of interactions between plant phenols and food macronutrients is a very important topic. In the present review, we summarise current knowledge, with a special focus on the in vitro and in vivo effects of food macronutrients on the bioavailability and bioactivity of polyphenols. The mechanisms of interactions between polyphenols and food macronutrients are also discussed. The evidence collected in the present review suggests that when plant phenols are consumed along with food macronutrients, the bioavailability and bioactivity of polyphenols can be significantly affected. The protein -polyphenol complexes can significantly change the plasma kinetics profile but do not affect the absorption of polyphenols. Carbohydrates can enhance the absorption and extend the time needed to reach a maximal plasma concentration of polyphenols, and fats can enhance the absorption and change the absorption kinetics of polyphenols. Moreover, as highlighted in the present review, not only a nutrient alone but also certain synergisms between food macronutrients have a significant effect on the bioavailability and biological activity of polyphenols. The review emphasises the need for formulations that optimise the bioavailability and in vivo activities of polyphenols.

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“…For example, the interference of some foods and even nutrients on the bioavailability and bioactivity of phenolic matrices is doubtless established, with milk being one of the most studied. Several reports have evidenced that milk interferes with the antioxidant potential of enriched-phenolic matrices, including blueberries (Serafini et al, 2009), tea (Langley-Evans, 2000aLorenz et al, 2007) and chocolate (Serafini et al, 2003). However, other authors have also reported contradictory results for the same phenolic matrices (Hof, Kivits, Weststrate, & Tijburg, 1998;Hollman, Hof, Tijburg, & Katan, 2001;Leenen, Roodenburg, Tijburg, & Wiseman, 2000).…”

Section: Benefits and Constraints Beyond Human Metabolismmentioning

confidence: 99%

In vivo antioxidant activity of phenolic compounds: Facts and gaps

Martins

Barros

Ferreira

2016

Trends in Food Science & Technology

265

159

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Background: Numerous diseases have been related with free radicals overproduction and oxidative stress. Botanical preparations possess a multitude of bioactive properties, including antioxidant potential, which has been mainly related with the presence of phenolic compounds. However, the mechanisms of action of these phytochemicals, in vivo effects, bioavailability and bio-efficacy still need research.Scope and Approach: The present report aims to provide a critical review on the aspects related with the in vivo antioxidant activity of phenolic extracts and compounds from plant origin.Key findings: Biological functions beyond the human metabolism were discussed, comparing in vivo vs. in vitro studies, as also focusing the conditioning factors for phenolic compounds bioavailability and bio-efficacy. Furthermore, an upcoming perspective about the use of phytochemicals as life expectancy promoters and anti-aging factors in human individuals was provided.Conclusions: Overall, and despite all of those advances, the study of the biological potential of numerous natural matrices still remains a hot topic among the scientific community. In fact, the available knowledge about the responsible phytochemicals for the biological potential, their mechanisms of action, the establishment of therapeutic and prophylactic doses, and even the occurrence of biochemical inter-relations, is considerable scarce.

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Antioxidant activity of blueberry fruit is impaired by association with milk

Cited by 105 publications

References 45 publications

Ayurvedic Dietary Principles in Prevention and Management of Diabetes: A Review

Ayurvedic Dietary Principles in Prevention and Management of Diabetes: A Review

Interaction of plant phenols with food macronutrients: characterisation and nutritional–physiological consequences

In vivo antioxidant activity of phenolic compounds: Facts and gaps

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