Antioxidant activity-guided isolation of constituents from Euphorbia gaditana Coss. and their antioxidant and tyrosinase inhibitory activities

Abstract

Highlights A phytochemical study of Euphorbia gaditana was carried out. Two previous unreported compounds type acetophenone and α-pyrone, along with 29 known compounds were identified. An antioxidant activity-guided isolation was performed using DPPH and CUPRAC assays. All extracts and isolated compounds were evaluated for their antioxidant activity. The tyrosinase inhibitory activity was estimated for the two previous unreported molecules.

Antioxidant activity of polyphenolic compounds obtained from Euphorbia antisyphilitica by-products

“…native from the Algerian Sahara, has a lower IC 50 value (7.20 ± 0.25 μg mL −1 ) than the values reported in our study [ 29 , 30 ]. In addition, Euphorbia gaditana extracts (cultivated in Europe) obtained IC 50 values varying with applied solvent with a range between 8.28 ± 0.88 μg mL −1 and 200 μg mL −1 [ 31 ]. The antioxidant activity of Copernicia prunifera (family Arecaceae), a related plant in the wax industry that is used for carnauba wax extraction, has been evaluated in a previous study in which the registered IC 50 was 50.70 μg mL −1 for ethanolic extracts [ 32 ].…”