2014
DOI: 10.1016/j.bionut.2014.04.006
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Antioxidant activity and anticancer effect of bioactive peptide from enzymatic hydrolysate of oyster (Saccostrea cucullata)

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Cited by 125 publications
(56 citation statements)
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“…After hydrolysis was performed using flavourzyme and benase, the antioxidant activity of the oyster byproduct hydrolysate increased, but spray drying did not significantly affect the antioxidant activity (P >0.05). The antioxidant peptides separated from the enzyme hydrolysate of the oyster protein has been described in previous studies (Umayaparvathi et al, 2014;Wang et al, 2014). On our study, enzyme hydrolysis enhanced the flavor and increased the antioxidant activity of the seasoning powder to some extent.…”
Section: Dpph Free Radical Scavenging Capacitysupporting
confidence: 73%
See 1 more Smart Citation
“…After hydrolysis was performed using flavourzyme and benase, the antioxidant activity of the oyster byproduct hydrolysate increased, but spray drying did not significantly affect the antioxidant activity (P >0.05). The antioxidant peptides separated from the enzyme hydrolysate of the oyster protein has been described in previous studies (Umayaparvathi et al, 2014;Wang et al, 2014). On our study, enzyme hydrolysis enhanced the flavor and increased the antioxidant activity of the seasoning powder to some extent.…”
Section: Dpph Free Radical Scavenging Capacitysupporting
confidence: 73%
“…Ots proteins are composed of various amino acids and a high taurine content (Je et al, 2005). Dyster is also rich in ω-3 unsaturated fatty acids and polyunsaturated fatty acids, which constitute approximately 50% of its total fatty acids (Cruz-Romero et al, 2008), Dyster extract performs many functions, including anti-bacterial (Defer et al, 2013;Liu et al, 2008), antihypertensive (Qian et al, 2008), anti-oxidation (Umayaparvathi et al, 2014;Wang et al, 2014), and anti-cancer activities (Umayaparvathi et al, 2014), ACE inhibition (Wang et al, 2008b), and DNA damage repair (Qian et al, 2008). Therefore, oyster is globally considered as valuable seafood with high nutritional value.…”
Section: Introductionmentioning
confidence: 99%
“…Many peptides also showed effective anticancer activities as reported by Jumeri and Kim, Lee et al ., Aleman et al . and Umayaparvathi et al …”
Section: Introductionmentioning
confidence: 62%
“…Cancer is one of the major causes of death in humans, and oxidative stress is closely related to a variety of human diseases including cancers . Therefore, antioxidant materials have been suggested as suitable candidates for preventing cancer and other diseases . Because the materials that contain both antioxidant and anticancer activities are very useful in treating or preventing cancers, many studies have been conducted to search for such materials, especially from natural resources …”
Section: Introductionmentioning
confidence: 99%
“…However, the lack of a dose dependent decrease in cell proliferation following treatment of RAW264.7 cells with increasing concentrations of Alcalase hydrolysate suggests that this hydrolysate did not display antiproliferative activity beyond 0.005% w/v. Previous studies have used the comet assay, which measures DNA damage, as an index of apoptosis in cells (Mancinelli et al, ; Woods, Young, Gilmore, Morris, & Bilton, ; Umayaparvathi et al, ). None of the hydrolysates in the present study, when tested alone in the comet assay at a higher concentration (0.1% w/v), induced DNA damage (Figure a).…”
Section: Resultsmentioning
confidence: 99%