Antioxidant Activities of Raw and Nano Turmeric (Curcuma longa L.) Powders

Abdel-Fattah, A.A.; Tawfik, M. F.

doi:10.21608/jfds.2016.46054

Cited by 3 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the current work, CONC showed superior in vitro anti‐inflammatory through the inhibition of COX‐1/COX‐2 compared to CUR and celecoxib even in lower minimal inhibitory concentration. This might be because nanoparticles are more soluble and capable of reaching cells than their initial products were (Abdel Fattah & Tawfik, 2016). OS and inflammatory processes go hand in hand.…”

Section: Discussionmentioning

confidence: 99%

Maternal supplementation of curcumin‐olive oil nanocomposite improves uteroplacental blood flow, placental growth and antioxidant capacity in goats

El‐Sherbiny,

Samir,

Youssef

et al. 2024

Animal Physiology Nutrition

View full text Add to dashboard Cite

This experiment was designed to investigate the impact of curcumin‐olive oil nanocomposite (CONC) supplementation on uteroplacental hemodynamics and ultrasonographic measurements as well as maternal oxidative status in midgestating goats. Twelve synchronized pregnant goats (85.58 ± 1.08 days of gestation; mean ± SD) were uniformly assigned to two groups (n = 6/group); the first group received daily oral supplementation of CONC (3 mg/kg body weight; nanocurcumin [NC] group) for 32 days, and the second group was offered physiological saline (control) following the NC group timeline. The goats of both groups were examined at 3‐day intervals for middle uterine (MUA) and umbilical (UMA) arteries hemodynamics (pulsatility index [PI], resistive index [RI], systole/diastole [S/D] and blood flow rate [BFR]) and diameters, uteroplacental thickness (UPT), placentomes' diameter (PD) and echogenicity, steroid hormones (progesterone and estradiol 17β), oxidative biomarkers (total antioxidant capacity [TAC], catalase [CAT], malondialdehyde [MDA]), nitric oxide (NO) and blood cells DNA integrity. The UPT (p = 0.012) and PD (p = 0.021) values were higher in the NC group than in their counterparts' control group (D11–32). There were increases in diameter (p = 0.021 and p = 0.012) and decreases (p = 0.021, p = 0.016 and p = 0.041 [MUA]; p = 0.015, p = 0.023 and p = 0.011 [UMA] respectively) in Doppler indices (PI, RI and S/D) of the MUA and UMA in the NC group compared to the control group (D14–32). On D20–32 (MUA) and D14–32 (UMA), the NC goats had higher BFR than the control group (p = 0.021, 0.018 respectively). The means of blood cells with fragmented DNA were lower (p = 0.022) in the NC group than in the control group on Days 8 and 21 postsupplementation. There were increases in CAT and NO (D20–32; p = 0.022 and p = 0.004 respectively), and TAC (D17–32; p = 0.007) levels in the NC goats compared to the control ones. The NC group had lower (p = 0.029) concentrations of MDA than the control group on Day 20 postsupplementation onward. In conclusion, oral supplementation of CONC improved uteroplacental blood flow and the antioxidant capacity of midgestating goats.

show abstract

Section: Discussionmentioning

confidence: 99%