Antioxidant Activities of Natural Vitamin E Formulations

Naguib, Yousry M. A.; Hari, Siva P.; Passwater, Richard A.; Huang, Dejian

doi:10.3177/jnsv.49.217

Cited by 19 publications

(13 citation statements)

References 12 publications

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“…This result is similar to values of 2510 mmol TE/g dietary supplement (Wu et al, 2004) or 1300-2030 mmol TE/g vitamin E formulation (Naguib et al, 2003). Average milk volumes consumed by 1-6-month-old infants, who are exclusively breast-fed by well-nourished mothers, is approximately 750-850 g/day (Butte et al, 1991;Dewey et al, 1991), an intake that is mostly controlled by infant demand (Dewey et al, 1991) and the caloric density of the mother's milk (Butte et al, 1991).…”

Section: Discussionsupporting

confidence: 91%

Use of ORAC to assess antioxidant capacity of human milk

Sáenz

Elisia

Innis

et al. 2009

Journal of Food Composition and Analysis

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Section: Discussionsupporting

confidence: 91%

Use of ORAC to assess antioxidant capacity of human milk

Sáenz

Elisia

Innis

et al. 2009

Journal of Food Composition and Analysis

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“…In vitro ORAC values correlated positively with glutathione concentration (Pieri et al 1994;Jiao and Wang 2000). Also a-tocopherol has been shown to contribute ORAC (Cao et al 1993;Balakrishnan et al 2003;Naguib et al 2003). However, the association of GSH and a-tocopherol concentrations with ORAC has not been studied in an exercise model until now.…”

Section: Discussionmentioning

confidence: 88%

“…The oxygen radical absorbance capacity (ORAC) assay for the measurement of antioxidant capacity may have an advantage because of its clinical relevance, reliability, repeatability and low cost . The major contributors to ORAC in plasma are uric acid, ascorbic acid and possibly glutathione and a-tocopherol (Cao et al 1993;Balakrishnan et al 2003;Naguib et al 2003). The contribution of vitamin C and uric acid in ORAC has been previously well demonstrated (Cao et al 1993;Jiao and Wang 2000;White et al 2001), but there is little information on the contribution of GSH and alpha tocopherol on total antioxidant capacity, especially during exercise.…”

Section: Introductionmentioning

confidence: 99%

Oxygen radical absorbance capacity (ORAC) and exercise-induced oxidative stress in trotters

Kinnunen

Hyyppä²,

Lehmuskero

et al. 2005

Eur J Appl Physiol

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Strenuous exercise is a potent inducer of oxidative stress, which has been suggested to be associated with disturbances in muscle homeostasis, fatigue and injury. There is no comprehensive or uniform view of the antioxidant status in horses. We have previously shown that moderate exercise induces protein oxidation in trotters. The aim of this study was to measure the antioxidative capacity of the horse in relation to different antioxidant components and oxidative stress markers after a single bout of moderate exercise to elucidate the mechanisms of antioxidant protection in horses. Eight clinically normal and regularly trained standard-bred trotters were treadmill-exercised for 53 min at moderate intensity. Blood samples were collected prior to and immediately after exercise and at 4 and 24 h of recovery. Muscle biopsies from the middle gluteal muscle were taken before exercise and after 4 h of recovery. Acute induction of oxygen radical absorbance capacity (ORAC) did not prevent exercise-induced oxidative stress, which was demonstrated by increased lipid hydroperoxides (LPO). Pre-exercise ORAC levels were, however, a determinant of total glutathione content of the blood after 4 and 24 h of recovery. Furthermore, baseline ORAC level correlated negatively with 4-h recovery LPO levels. Our results imply that horses are susceptible to oxidative stress, but a stronger antioxidant capacity may improve coping with exercise-induced oxidative stress.

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“…A good example is vitamin E, which was discovered in 1922 by Evans and Bishop. Vitamin E is a major lipid‐soluble antioxidant in vitro and as such might protect body lipids, especially membrane lipids, phospholipids, and lipoproteins from oxidation in vivo (Naguib et al, 2003). The latter is currently strongly debated.…”

Section: Mass Spectrometry In Nutritionmentioning

confidence: 99%

Mass spectrometry in nutrition: Understanding dietary health effects at the molecular level

Kussmann

Affolter

Nagy

et al. 2007

Mass Spectrometry Reviews

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In modern nutrition research, mass spectrometry has developed into a tool to assess health, sensory as well as quality and safety aspects of food. In this review, we focus on health-related benefits of food components and, accordingly, on biomarkers of exposure (bioavailability) and bioefficacy. Current nutrition research focuses on unraveling the link between dietary patterns, individual foods or food constituents and the physiological effects at cellular, tissue and whole body level after acute and chronic uptake. The bioavailability of bioactive food constituents as well as dose-effect correlations are key information to understand the impact of food on defined health outcomes. Both strongly depend on appropriate analytical tools to identify and quantify minute amounts of individual compounds in highly complex matrices-food or biological fluids-and to monitor molecular changes in the body in a highly specific and sensitive manner. Based on these requirements, mass spectrometry has become the analytical method of choice with broad applications throughout all areas of nutrition research. The current review focuses on selected areas of application: protein and peptide as well as nutrient and metabolite analysis. #

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Antioxidant Activities of Natural Vitamin E Formulations

Cited by 19 publications

References 12 publications

Use of ORAC to assess antioxidant capacity of human milk

Use of ORAC to assess antioxidant capacity of human milk

Oxygen radical absorbance capacity (ORAC) and exercise-induced oxidative stress in trotters

Mass spectrometry in nutrition: Understanding dietary health effects at the molecular level

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