Antioxidant Activities of Molokhia (Corchorus olitorius L.) Extracts

Öztürk, Nilgün; Savaroğlu, Filiz

doi:10.1007/978-3-540-95991-5_48

Cited by 5 publications

(1 citation statement)

References 16 publications

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“…These are like superoxide, hydroxyl radical, singlet oxygen, and these move in the body and cause destruction of the body cells [10]. The enzymes which are produced in the body like antioxidant enzymes, these scavenge or destroy the free radicals which are harmful for our body [11,12].…”

Section: Introductionmentioning

confidence: 99%

In-vitro Antioxidant and Antidiabetic Properties of Corchorus olitorius Leaves and Seed Ethanol Extract

Britina

Sridevi

Jayaraman

2021

JPRI

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Background: Medicinal herbs have been widely used in therapeutic applications for various diseases in today’s world. These herbs are used by village folk medicine, but without scientific evidence. Corchorus olitorius, also known as jute mallow is a herb that possesses many curing effects like pain, fever and many other diseases like cystitis and tumour etc. Objective: The objective of the study was to elucidate the effects of corchorus olitorius as antioxidant and antidiabetic. Materials and Methods: In Vitro Evaluation of antidiabetic and antioxidant properties were conducted using various tests. Alpha - amylase inhibitory activity and alpha glucosidase inhibitory activity for antidiabetic activity and DPPH free radical scavenging assay for antioxidant property was performed. The results were compared with standard metformin and aspirin respectively. Results: Results showed a dose dependent increase in alpha amylase inhibitory activity with concentration ranging from 100-500 micro/ml. Results showed a dose dependent increase in alpha glucosidase inhibitory activity with concentration ranging from 100-500 micro/ml. Results showed a dose dependent increase in DPPH free radical scavenging activity with concentration ranging from 100-500 micro/ml. Conclusion: The results showed an innovative finding that ethanolic seed extract of corchorus olitorius has great potential as antidiabetic and antioxidant property which can be used as novel innovative natural medication in the medical field rather than using any artificial synthetic drug which causes many other side-effects like allopathic drugs.

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Section: Introductionmentioning

confidence: 99%

In-vitro Antioxidant and Antidiabetic Properties of Corchorus olitorius Leaves and Seed Ethanol Extract

Britina

Sridevi

Jayaraman

2021

JPRI

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Pharmacological and phytochemical biodiversity of Corchorus olitorius

et al. 2022

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Corchorus olitorius L. Leaf Extract Protects Rats from Acrylamide-Induced Hepatic Injury

Alkhalifah

Ahmed

2021

Curr Res Nutr Food Sci

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Acrylamide is a water-soluble compound that forms during the high-temperature cooking of starchy foods and has carcinogenic, neurotoxic, and genotoxic properties. Also, short-term exposure to acrylamide has been shown to cause significant hepatic injury in laboratory animals, along with disruption of antioxidant defense mechanisms due to excessive ROS production. Therefore, dietary antioxidants are believed to be useful in combating the negative effects of acrylamide. Corchorus olitoris L., also known as molokhia in Arabic, is a leafy vegetable which is shown to possess potent antioxidant and organoprotective properties. In this study, rats were administered with an aqueous extract of molokhia leaves to see if it could protect them against acrylamide-induced hepatic damage. Hepatic injury markers included serum total protein, total bilirubin, ALT, AST, and ALP, while oxidative stress markers included MDA, GSH, CAT, and SOD after dosing with three levels of extract (100, 250, and 500 mg/kg) for 21 days. Results indicated that the extracts substantially reduced elevated levels of bilirubin, ALT, AST, ALP, and MDA to normal levels at all doses. The extracts also brought serum protein, GSH, CAT, and SOD levels back to normal. Although the restoration of serum hepatic enzyme levels was dose dependent, no specific dose dependent relationship was found for serum proteins, MDA, GSH, CAT, or SOD activities. The study's findings show that molokhia leaves extract protects against acrylamide-induced hepatic damage by virtue of its good radical scavenging and anti-lipiperoxidative properties conferred by phenolics, flavonoids, and alkaloids.

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Antioxidant Activities of Molokhia (Corchorus olitorius L.) Extracts

Cited by 5 publications

References 16 publications

In-vitro Antioxidant and Antidiabetic Properties of Corchorus olitorius Leaves and Seed Ethanol Extract

In-vitro Antioxidant and Antidiabetic Properties of Corchorus olitorius Leaves and Seed Ethanol Extract

Pharmacological and phytochemical biodiversity of Corchorus olitorius

Corchorus olitorius L. Leaf Extract Protects Rats from Acrylamide-Induced Hepatic Injury

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