Antioxidant Activities and Chemical Constituents of Flavonoids from the Flower of Paeonia ostii

Abstract

Paeonia ostii is a traditional medicinal plant popularly used in China. This study intended to evaluate the antioxidant properties and the chemical components of the flavonoid-rich extracts from the flowers of P. ostii. The results showed that the flavonoid-rich extracts from the flowers of P. ostii had strong scavenging capacities on 2,2′-Azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS), hydroxyls, superoxide anions, and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals in a dose-dependent manner. Five flavonoids, dihydrokaempferol (1), apigenin-7-O-β-d-glucoside (2), apigenin-7-O-β-d-neohesperidoside (3), kaempferol-7-O-β-d-glucopyranoside (4), and kaempferol-3-O-β-d-glucopyranosyl-7-O-β-d-glucopyranoside (5), were isolated from the flavonoid-rich extracts of the flowers of P. ostii. High-performance liquid chromatography (HPLC) analysis revealed that compounds 3 and 4 were abundant in the P. ostii flower and in flavonoid-rich extracts. The main components of the flower of P. ostii are flavonoids. The high antioxidant activity of the flavonoid-rich extracts may be attributed to the high content of flavonoids. The five isolated flavonoids were the primary antioxidant ingredients, and may play important roles in the strong antioxidant activities of this flower. Based on the obtained results, the flower of P. ostii could be a potential source of natural antioxidants in food and pharmaceutical applications.

Green synthesis palladium nanoparticles mediated by white tea (<em>Camellia sinensis</em>) extract with antioxidant, antibacterial, and antiproliferative activities toward the human leukemia (MOLT-4) cell line

“…It is assumed that the content of phenolic and flavonoid compounds of the extract and Pd@W.tea NPs would afford them promising radical scavenging activity because these compounds are known to be scavengers of DPPH, OH, and NO. 25,31,32 The radical scavenging activities of white tea extract for DPPH was high even at low doses and was not dose-dependent (Figure 7). On the other hand, the DPPH scavenging activity of Pd@W.tea NPs was low at low concentrations and only began to approach antioxidation efficacy of white tea extract only after reaching high doses.…”

Flower extracts from Paeonia decomposita and Paeonia ostii inhibit melanin synthesis via cAMP‐CREB‐associated melanogenesis signaling pathways in murine B16 melanoma cells

“…A recent study showed that the extracts from the flowers of P. ostii have numerous antioxidant properties and these properties are closely related to the high content of flavonoids (Zhang et al, ). Moreover, other studies suggested that the extracts from the root cortex of P. suffruticosa significantly reduced the cellular tyrosinase and DOPA oxidase activity as well as melanin content in B16 cells, which could be due to its abundant phenolic and flavonoid content‐induced antioxidant activities (Ding et al, ).…”

“…Eleven flavonoids were isolated and their structures were elucidated as chrysoeriol‐7‐ O ‐glucopyranoside (1), kaempferol‐7‐ O ‐glucopyranoside (2), dihydrokaempferol‐7‐ O ‐glucopyranoside (3), luteolin‐7‐ O ‐glucopyranoside (4), apigenin‐7‐ O ‐neohesperidoside (5), apigenin‐7‐ O ‐glucopyranoside (6), kaempferol‐3‐ O ‐glucopyranoside (7), apigenin (8), kaempferol (9), dihydrokaempferol (10), and peonin (11) (Wang et al, ; Zhang et al, ; Zhao et al, ). Among them, compounds 2 and 7 were abundant in the P. ostii flower and in flavonoid‐rich extracts (Zhang et al, ). We suspect that the flavonoid content of Pd and Po could include but not be limited to these contents, and it differs in different parts of the flower.…”

“…Among them, P. ostii and P. decomposita are cultured in a relatively large area in Dianjiang county, Chongqing City, China. In November 2013, the National Health and Family Planning Commission of the People’s Republic of China approved the flower of P. ostii as a novel food resource (Zhang et al, ). P. decomposita seeds provide abundant ALA to balance the ω6/ω3 ratio which can be an excellent resources of edible oil (Yu, Du, Yuan, & Hu, ).…”

Antioxidant, hypoglycemic and anti-diabetic activities of Ziziphus spina-christi (L) Willd (Rhamnacae) leaf extract

“…Group 1, the diabetic control, was administrated 1 mL normal saline, group 2 was administered 1 mg/kg glibenclamide, and the other groups were administered ZSC-1, ZSC-2 and ZSC-3 at 250 and 500 mg/kg, respectively. The animals were loaded with glucose (3 g/kg) [11] and blood samples were collected immediately before drug administration and at 30, 60, 90 and 120 min after drug administration.…”