Antioxidant Actions of Phenolic Compounds Found in Dietary Plants on Low-Density Lipoprotein and Erythrocytes in Vitro

Abstract

In view of their protective effects on LDL and erythrocytes against oxidative damage, these phenolic compounds might have potential applications in prooxidant state-related cardiovascular disorders.

Levels of two oxidative stress indicators of human sickle erythrocytes incubated in aqueous extracts of Anacardium occidentale, Psidium guajava and Terminalia catappa.

“…Furthermore, relatively lower MDA concentrations of the test samples, compared to the control ones, at the given time intervals, revealed that lipid peroxidation was retarded by the three plant extracts in relation to their corresponding concentrations. The present findings are in concord with the report of Lam et al [46] . They noted that gamma sickle erythrocytes must have contributed to the poor and insignificant capacities of the three plant extracts to reduce the levels of erythrocyte Met.Hb%.…”

“…www.antiox.org irradation-induced oxidative stress indicators were significantly reduced in rats after orally administered with Aloe vera. Prevoius findings have attributed the capacities of Zingiber officinale, Aloe vera and Rheum rhabarbarum extracts to reduce lipid peroxidation to the presence of phenolic compounds in these plants [46,62] . Also, membrane protective activities of diverse plant extracts have been attributed to their antioxidant content and capacity to impede membrane lipid peroxidation [47,63,64] .…”

“…Similarly, scavenging activities for free radicals by natural products of plant origin have been widely reported. [1,28,[45][46][47][48][49] . This study has ascertained the level of oxidative stress by estimating the concentrations of two oxidative stress indicators, namely, MDA and methaemoglobin of sickle erythrocytes incubated in aqueous extracts of three medicinal plants: Anacardium occidentale, Psidium guajava and Terminalia catappa.…”

Protective roles of Cimin grape tissues on oxidative stress markers in the cellular system model

“…The decrease in TBARS formation with the extract samples (seed, skin, and juice) compared to the control group without extract is almost 12%. A number of studies have demonstrated that the treatment of erythrocyte membrane with H 2 O 2 results in peroxidation and disruptions of their structures and functions, including changes in ATPase activity and membrane fluidity (32,33). Many pathophysiological events such as inflammation, aging, and ischemia/reperfusion are attributed to this peroxidation.…”

Barbaloin: A concise report of its pharmacological and analytical aspects

“…Barbaloin protected Ca 2+ -ATPase and protein sulfhydryl groups on erythrocyte membranes against oxidative attack by tBHP/hemin [9] . Effect of barbaloin on nitric oxide (NO), tumour necrosis factoralpha (TNF-alpha) and interleukin were investigated and found significant inhibitory potential.…”