Antiobesity Effect of Major Korean Spices (Red Pepper Powder, Garlic and Ginger) in Rats Fed High Fat Diet

Yoon, Ji-Young; Jung, Keun-Ok; Kil, Jeung-Ha; Park, Kun-Young

doi:10.3746/jfn.2005.10.1.058

Cited by 9 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Yoon et al [51] reported that supplementation of spices (red pepper, garlic and ginger) in the high fat diet showed more effective of the lipids improving for the fat tissue and serum in the garlic compared to pepper or ginger. The phenolic compounds in plant kingdom decreased lipid level in serum [48] and liver tissues [19], curtailing the occurrence of cardiovascular disease.…”

Section: Alt and Ast Activitiesmentioning

confidence: 99%

“…Thus, there is a growing attention on the way to improve obesity using phyto-nutrient that does not cause side-effects, among which garlic is known to effective for the control of lipid metabolism and obesity [1,16,24,31,51]. A major bioactive substances of garlic (Allium sativum L.) are an organic sulfur compounds containing allicin [11,18,22], which has the cardioprotective function among others [25].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of the Red Garlic Extract for Anti-Obesity and Hypolipidemic in Obese Rats Induced High Fat Diet

Lee¹,

Kim²,

Ryu³

et al. 2011

Journal of Life Science

View full text Add to dashboard Cite

This study tested the anti-obesity and hypolipidemic effects of red garlic extract in obese rats induced by a high fat diet over a period of 4 weeks. Red garlic extract of 15 brix was added in 1, 3, 5 and 7% ratios in diets. The obesity index and body fat content significantly decreased in rats fed a diet with over 3% red garlic extract compared to the control group. There was no significant difference in weight of visceral and epididymal fat in rats fed red garlic extract. Total lipid and triglyceride levels in serum were significantly decreased in a dose-dependent manner, and AI and CRF also fell. ALT and AST activities in groups fed red garlic extract were decreased compared to the control group. Total lipid level in liver tissue of the groups fed 5-7% red garlic extract exhibited a significant decrease compared to the control group. Total cholesterol and triglyceride levels in feces were significantly increased in rats fed a diet with over 5% red garlic extract. Lipid peroxide levels were significantly decreased in the groups fed diets with 5-7% red garlic and antioxidant activity in serum was significantly increased in the group fed a diet with 7% red garlic extract compared to the control group. Our results suggest that red garlic extract could have anti-obesity and hypolipidemic effects for suppressing obesity index and decreasing lipid profiles. IntroductionAs the choice for a high-calorie and high-fat diet increases due to the economic stability and affluence, so does the occurrence of metabolic disease caused by over-weight [27]. Obesity is the condition under which surplus energy is accumulated as lipids, which is attributable to the increase of energy intake and the decrease of consumption. From the balance is lost, obesity or hyperlipidemia develops, leading to a serious disease. In Korea, the social and economic cost incurred by the increase of obese population rises annually. Given that 40% of people who die by circulating system disease including atherosclerosis, cerebro-, cardio-vascular complications, hypertention, diabetes and functional depression of certain organs are obese, it is necessary to take a fundamental measure to improve the situation [47].Although the drug therapy proved to be effective as a behavior correction therapy used for the control of lipid metabolism in obese, it accompanies side-effects such as headaches, insomnia, and vomiting [29]. Thus, there is a growing attention on the way to improve obesity using phyto-nutrient that does not cause side-effects, among which garlic is known to effective for the control of lipid metabolism and obesity [1,16,24,31,51]. A major bioactive substances of garlic (Allium sativum L.) are an organic sulfur compounds containing allicin [11,18,22], which has the cardioprotective function among others [25]. Reportedly in Korea, the bioactive effect is elevated through the heat-treatment which turns fresh garlic into aged black garlic [22,46] supplemented with 5% red garlic extract, RG-7: supplemented with 7% red garlic extract. production of t...

show abstract

Section: Alt and Ast Activitiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of the Red Garlic Extract for Anti-Obesity and Hypolipidemic in Obese Rats Induced High Fat Diet

Lee¹,

Kim²,

Ryu³

et al. 2011

Journal of Life Science

View full text Add to dashboard Cite

show abstract

“…The common use of the various medical herbals and spices as Red Pepper, Ginger, turmeric and others has caught the attention to know their health impacts and to know the possibility of using it in the different medical applications for different diseases as an alternative or with chemotherapy putting into consideration potions and their amounts (Yoon et al, 2005).…”

Section: -Medical Use Of the Red Peppermentioning

confidence: 99%

“…Reducing the weight of the fats surrounding liver and kidney is achieved by the influence of the red pepper on the metabolic enzymes and undermine fats, increase its secretion and increase fats move form fatty tissues to bloodstream to get metabolic it, and then thrown out of the body (Yoon et al, 2005).…”

Section: -1: Effect Of Red Pepper On the Biochemical Variablesmentioning

confidence: 99%

Antioxidants and Biochemical Effects of Oral Administration of Red Pepper Aqueous Extract on Rabbit's Liver Treated with Cholesterol

Al-Ishlash¹,

Al-Kattan²

2019

وقائع الملتقي العلمي الدولي المعاصر

View full text Add to dashboard Cite

show abstract

“…It has been reported that garlic and its associated sulfur compounds suppress weight gain, and TG and cholesterol concentrations. They also affect the normalization of plasma lipids, reduction of blood pressure and glucose, and inhibition of platelet aggregation (10)(11)(12)(13)(14). Sulfur compounds from garlic are known as alliin, allicin (diallyl thiosulfinate), diallyl sulfinate (DAS), diallyl disulfinate (DADS), etc.…”

Section: Introductionmentioning

confidence: 99%

Anti-Obesity Effect of Garlic-added Kochujang in 3T3-L1 Adipocytes

Kong¹,

Park²

2008

JFN

Self Cite

View full text Add to dashboard Cite

In order to develop a functionally improved kochujang with antiobesity effects, garlic-added kochujang was prepared with freeze-dried garlic powder and followed by fermentation for 60 days at 30 o C. Antiobesity effect of the garlic-added kochujang was investigated by measuring the leptin secretions and mRNA expression levels of obesity-related gene such as TNFα, PPARγ, C/EBPα, and SREBP1c, in cultured 3T3-L1 adipocytes. Fermentation of garlic-added kochujang led to decreased levels of leptin secretions and reduced the mRNA expression levels of TNFα, PPARγ, C/EBPα, and SREBP1c in the 3T3-L1 adipocytes. Accordingly, these results suggest that the addition of garlic to kochujang has a potential as a valuable functional food for controlling obesity.

show abstract

Antiobesity Effect of Major Korean Spices (Red Pepper Powder, Garlic and Ginger) in Rats Fed High Fat Diet

Cited by 9 publications

References 6 publications

Effects of the Red Garlic Extract for Anti-Obesity and Hypolipidemic in Obese Rats Induced High Fat Diet

Effects of the Red Garlic Extract for Anti-Obesity and Hypolipidemic in Obese Rats Induced High Fat Diet

Antioxidants and Biochemical Effects of Oral Administration of Red Pepper Aqueous Extract on Rabbit's Liver Treated with Cholesterol

Anti-Obesity Effect of Garlic-added Kochujang in 3T3-L1 Adipocytes

Contact Info

Product

Resources

About