Antinutriments et propriétés nutritionnelles in vivo de Cochlospermum tinctorium A. Rich. (Bixaceae) chez les jeunes rats (Rattus norvegicus L.)

Abstract

Cochlospermum tinctorium A. Rich. (Bixaceaee) est une plante répandue dans la bande sahélosoudanienne africaine. Sa racine tubéreuse est utilisée soit comme aliment de soudure et soit comme un organe végétal hépatoprotecteur. Cette racine a été prélevée à Mindaoré/Fianga (Tchad), réduite en poudre et soumise à des analyses chimiques des antinutriments selon des méthodes bien documentées avant d'être testée sur cinq groupes de rats albinos (Rattus norvegicus L). A la fin de l'expérimentation, des analyses biochimiques et hématologiques ainsi que la pesée d'organes ont été effectuées. A un seuil de 5%, les résultats ont révélé des proportions importantes d'antinutriments dans la racine de C. tinctorium. Les corrélations entre ces derniers et les paramètres étudiés et l'évaluation de la masse des différents organes des rats a montré que la consommation de la racine de C. tinctorium n'est pas nocive à l'organisme animal mais relance plutôt l'activité des organes vitaux tels que le foie. En définitive, la consommation de C. tinctorium a un effet sur le statut pondéral et glycémique et sur le cholestérol total du rat. Néanmoins, il est intéressant d'étudier l'histologie des organes vitaux de l'animal testé.

Influence of aqueous leafy stem extract of Cochlospermum tinctorium A. Rich. (Cochlospermaceae) on liver injury induced by subacute exposure of rats to carbon tetrachloride

“…ese results are not consistent with those of Ndouyang et al who found that the root powder of C. tinctorium increases the serum lipid levels in rats and thereby leading to a rise in the atherogenic index. [10] Attacks by free radicals cause acute and chronic liver toxicity, leading to necrosis, fibrosis, steatosis, and cirrhosis. [35] e metabolism of CCl4 by liver cells leads to the formation of free radicals which reduce the levels of antioxidant enzymes, increase malondialdehyde, and cause oxidative stress.…”

“…[9] Among these plants, we find Coclospermum tinctorium (Cochlospermaceae) which is a well-known plant in phytotherapy. [10][11][12][13] e rhizome of C. tinctorium is used against fever, hepatitis, inflammation, abdominal pain, helminth infections, and bilharziasis. [11] In Senegal and Niger, C. tinctorium is used to treat liver disease, but also rickets, colic, helminthiasis, and beriberi.…”

“…[16][17][18] Many studies have highlighted various properties of this plant. Ndouyang et al [10] have shown that the whole meal of C. tinctorium roots stimulates lipid accumulation in rats, has hypoglycemia and hypercholesterolemia effects, and also boosts the activity of the rat liver. Another study has demonstrated a strong in vitro radical scavenging activity of C. tinctorium root powder.…”

Relationship between Secondary Metabolites, Antiradical Activities, and Colour Characteristics of Cochlospermum Tinctorium A. Rich. (Bixaceae) Root

“…The plant materials, the fresh roots of Cochlospermum tinctorium were collected in the village of Mindaore (local name of the plant in Tupuri language: 'Belyewn'), at the Eastern of the region of Mayo-Kebbi in Chad. The sample was taken to the Laboratory of Biophysics, Food Biochemistry and Nutrition of ENSAI/ University of Ngaoundere Cameroon for unit operations by using separately two different processing as reported by Ndouyang et al (2018). The cuticle was discarded, and the first operation being a traditional household process consisted of reducing the inner matrix of the root in slices and of dividing the skin of the same root in small pieces; the second involved soaking processing of a part of the root inner matrix.…”

“…According to many authors, the root of Cochlospermum tinctorium (also called rhizome) is used in the prevention or treatment of malaria (Benoit et al, 1995;Guiguemde et al, 2000;Zederkopff-Ballin et al, 2002;Ahmadu et al, 2014), bacterial diseases (Ouattara et al, 2007;Tidjani et al, 2009;Magaji et al, 2010), hepatic affections such as jaundice, chronic hepatitis B (Etuk et al, 2009a;Akinloye et al, 2011;Akinloye et al, 2012;Musa et al, 2012). It is also used in controlling physiological disorders such as hyperglycemia (Ndouyang et al, 2018), convulsion (Maiha et al, 2009), inflammation and pain (Nergard et al, 2005;. In addition, the root of plants of the genus Cochlospermum used against viruses was also reported (Solon et al, 2012;Musa et al, 2012).…”