Antinuclear antibodies in systemic scleroderma.

哲雄, 佐々木; 秀貴, 小野; 弘, 中嶋

doi:10.2336/nishinihonhifu.52.1172

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1993

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“…as in our cases. The mean age of onset in SS was reported to be between 32 and 42 years [8,12,13]. So 4 of the 6 cases could be regarded as late-onset SS.…”

Section: Discussionmentioning

confidence: 99%

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Systemic Sclerosis (Scleroderma) Associated with Discoid Lupus erythematosus

Sasaki¹,

Nakajima²

1993

Dermatology

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Six patients with systemic sclerosis (SS) and discoid lupus erythematosus (DLE) were studied to determine whether such cases have some common clinical and laboratory findings. DLE preceded SS in all cases. Three patients had diffuse scleroderma with lung and esophagus involvements and the others limited scleroderma. Three patients had anti-topoisomerase-I and antiribonucleoprotein antibodies, 2 had either of them and the remaining anticentromere antibodies. Four had DLE located on the scalp, leading to alopecia. The other 2 had DLE on the face and extremities. No case fulfilled criteria for systemic lupus erythematosus (SLE). The present cases with SS and DLE, but without SLE, indicate that this type of systemic-cutaneous collagen disease overlap does exist and may be not so rare.

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“…as in our cases. The mean age of onset in SS was reported to be between 32 and 42 years [8,12,13]. So 4 of the 6 cases could be regarded as late-onset SS.…”

Section: Discussionmentioning

confidence: 99%

“…except for leukopenia in case 6. The fact that anti-Ki and anti-Topo-I antibodies in case 6 became positive before and around the onset of clinical symptoms of SS, respectively, corresponds well with each characteristic as a marker for overlap syn drome [13] or SS [ 13. 16].…”

mentioning

confidence: 99%

Systemic Sclerosis (Scleroderma) Associated with Discoid Lupus erythematosus

Sasaki¹,

Nakajima²

1993

Dermatology

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Antinuclear antibodies in systemic scleroderma.

Cited by 1 publication

References 6 publications

Systemic Sclerosis (Scleroderma) Associated with Discoid Lupus erythematosus

Systemic Sclerosis (Scleroderma) Associated with Discoid Lupus erythematosus

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