Antinociceptive Activity of &lt;i&gt;Vitis trifolia&lt;/i&gt;

Ahmed, Firoj; Rahman, KM Wahidur; Alam, Smm; Masud, Mohammad Mehedi

doi:10.3329/dujps.v6i2.689

Cited by 1 publication

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“…The antibacterial activity was investigated using Gram-positive bacteria ( Staphylococcus aureus , Staphylococcus epidermidis , Staphylococcus saprophyticus , Streptococcus pyogenes ) and Gram negative bacteria ( Plesiomonas shigelloides , Shigella dysenteriae , Vibrio cholera , Salmonella typhii , Shigella flexneri , Shigella boydii , Shigella sonnei , Pseudomonas aeruginosa ) by agar diffusion method (Bauer et al 1996; Ahmed et al 2003). These microorganisms were collected from the Microbiology Lab.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of pharmacological activity of Hibiscus tiliaceus

et al. 2016

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Hibiscus tiliaceus, locally known as Bhola was examined for phytochemical properties and its cytotoxic, antibacterial, analgesic and neuropharmacological activities using the ethanol extract of leaf and bark. The phytochemical analysis of the leaf extract indicated the presence of tannins, whereas bark extract indicated the presence of alkaloid, reducing sugar and tannins. A preliminary cytotoxicity of these extracts was determined by a simple and low cost assay using brine shrimp lethality. The leaf extract of the plant exhibited moderate cytotoxic effect (LC 50 : 20 µg/ml, LC 90 : 40 µg/ml) whereas the bark extract exhibited low cytotoxic effect (LC 50 : 50 µg/ml). In the analgesic test, the leaf extract showed comparatively high analgesic action than bark extract. There was no activity found in the leaf extract against the test bacterial strains, however bark extract exhibited a very little inhibitory effect on Staphylococcus aureus and Staphylococcus epidermidis. In the neuropharmacological test, the leaf and bark extract produced a decrease in both the time of onset of sleeping and the total sleeping time. The present study showed evidence that both leaf and bark extract of H. tiliaceus contain medicinally important bioactive compounds, thereby used as traditional medicine.

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Section: Methodsmentioning

confidence: 99%