Antimycobacterial activity of extracts of two Moroccan Cistus L. species

Haouat, Amina Cherif; Sqalli, Hakima; Farah, Abdellah; Haggoud, Abdellatif; Iraqui, Mohammed

doi:10.1007/s10298-013-0806-6

Cited by 7 publications

(8 citation statements)

References 57 publications

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“…For example, tea prepared from C. salvifolius L. herb (AL-KHALIL, 1995) has traditionally been used for the treatment of gout (AL-KHALIL, 1995) and ulcers (YESILADA et al, 1999). In Morocco, C. salvifolius also has been found to exhibit anti-bacterial activity against Mycobacterium aurum and Mycobacterium smegmatis (HAOUAT et al, 2013). Cistus incanus spp.…”

Section: Introductionmentioning

confidence: 99%

Comparison of antioxidant and antimicrobial activities of two cultivated Cistus species from Tunisia

Mahmoudi¹,

Aouadhi²,

Kaddour³

et al. 2016

Biosci. J.

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ABSTRACT:The secondary metabolite composition, antioxidant activities, and microbial inhibition properties of leaves of two Cistus species; C. monspeliensis and C. salvifolius were investigated using three solvent extracts (ethanol, hexane and distilled water). Ethanol extracts were most efficient at extracting phenolics, flavonoids and condensed tannins compared to hexane and distilled water for both Cistus species. A total antioxidant test (TAA) and two radical scavenging tests (DPPH and ABTS) indicated that the 70% ethanolic extract from C. salvifolius leaves had stronger antioxidant activity compared to the C. monspeliensis 70% ethanol extract, while the aqueous extract of C. monspeliensis was much stronger than the aqueous extract or the 70% ethanol extract of C. salvifolius. Overall, the polar extracts were more active in both species than the non-polar extracts. Thus aqueous ethanol extracts of the leaves of each Cistus species were tested for their ability to inhibit seven pathogenic microbial strains, including Escherichia coli ATCC 8739, Salmonella typhimurium NCTC 6017, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 29213, Enterococcus faecalis, Aspergillus niger, and Candida albicans. Leaf ethanol extracts from both species were active against each microbial species, but the C. monspeliensis leaf ethanolic extract was much more active against several microbial species than that of C. salvifolius. For example, the C. salvifolius 70% ethanol extract showed its highest antimicrobial activity against P. aeruginosa and A. niger (MIC 3.1 mg/ml and MBC 6.3 mg/ml for both), while the C. monspeliensis extract showed much higher overall activity against E. coli, P. aeruginosa and C. albicana. (MIC 6.25 mg/ml and MBC 12.5 mg/ml for all three). In conclusion, maceration with 70% ethanol was the most efficient method for extracting total polyphenols, flavonoids, and condensed tannins from the two Cistus species, and the aqueous-ethanol extracts displayed the highest antioxidant and antimicrobial activities. Hence, the aqueousethanolic extracts of both species may be considered as potential sources of natural antioxidants and antimicrobial agents.

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Section: Introductionmentioning

confidence: 99%

Comparison of antioxidant and antimicrobial activities of two cultivated Cistus species from Tunisia

Mahmoudi¹,

Aouadhi²,

Kaddour³

et al. 2016

Biosci. J.

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“…Quand à la concentration minimale bactéricide la plus faible égalant à 0.031% est enregistrée pour les HEs des plantes Mentha pulegium et Thymus satureioides (Chraibi et al, 2016), suivie par celle de l'HE de Thymus pallidus Batt étant de 0.08% (Sqalli et al, 2009), alors que la CMB d'HE de Mentha piperita vient au dernier rang avec une valeur de 0.5% contre M. smegmatis (Chraibi et al, 2017 Précédemment, il est rapporté par plusieurs recherches que ces molécules sont dotées d'un effet antimycobactérien (Haouat et al, 2013 ). Prenant par exemple, le cas de l'étude réalisée par Anand et ses collaborateurs (2006) ayant montré que l'épigallocatechin-3-gallate, un composant majeur des polyphénols du thé vert, inhibe la croissance de M. tuberculosis survivant à l'intérieur des macrophages humains via la régulation négative de l'expression d'un gène codant pour la coronine-1, appelée encore TACO (pour tryptophan aspartate containing coat protein) à travers l'inhibition de l'activité de facteur de transcription Sp1.…”

Section: Discussionunclassified

“…Elle possède des alcaloïdes et des polyphénols ayant un effet antimycobactérien contre M. smegmatis (Haouat et al, 2013).…”

Section: Activité Des Extraits Et/ou Des Huiles Essentielles Des Planunclassified

Effet Antimycobactérien Des Plantes Marocaines: Revue Générale

Zahir

Taghiam

2018

ESJ

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Tuberculosis is a major public health problem in the world. It is the leading cause of death from infectious diseases. The upsurge of this disease is mainly due to the emergence of multi-resistant and ultra-resistant strains of Mycobacterium tuberculosis. Hence, efforts to find out new antimycobacterial substances are needed. In this context, plants constitute an immense reservoir of original active molecules with interesting biological effects. Hence, they represent a promising way to discover substances that can possibly better control mycobacterial infections and reduce the emergence of bacterial resistance to anti-tubercular drugs. Consequently, our herein work focuses on the presentation of the antimycobacterial activity of the extracts and / or essential oils of 21 Moroccan plants, through the results analysis of scientific investigations carried out between 2007 and 2017 retained via an electronic navigation by using different databases (ScienceDirect, Pubmed, Scopus, Google Scholars and Google), thus revealing the efforts made by Morocco to fight against tuberculosis.

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“…Results show complete inhibition of these species against atypical mycobacteria and M. bovis. Even the lack of details and referenced methods to study the activity against this particular strain gives us hope that further research may eventually lead to potential agents [155,156].…”

Section: Antibacterial Effect Of Crude Extractsmentioning

confidence: 99%

A Review on Cistus sp.: Phytochemical and Antimicrobial Activities

Zalegh

Akssira

Bourhia

et al. 2021

Plants

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Resistance to drugs is reaching alarming levels and is placing human health at risk. With the lack of new antimicrobials drugs, infectious diseases are becoming harder to treat. Hence, there is an increasing awareness of active phytochemicals with therapeutic functions. The tremendous research interest on the Cistus L. genus includes numerous plants used in traditional medicine by people living around the Mediterranean Sea, also resulted in some interesting discoveries and written literature. This review aimed at gathering scientific literature about Cistus species, describing phytochemical profiles and the various pharmacological activities. We also extensively reviewed the antimicrobial activities, including antiviral, antiparasitic, antifungal, and antibacterial potentials of Essential Oils (EO), raw extracts as well as isolated compounds. Mechanisms of action along with methods used are also investigated in this review. Considering the findings of the Cistus species extracts, this genus offers an adequate reserve of active phytochemicals since many have been used to create drugs. Therefore, this review work can serve society by providing a global view on Cistus L. sp. regarding pharmacological potentials and their chemical profiles.

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Antimycobacterial activity of extracts of two Moroccan Cistus L. species

Cited by 7 publications

References 57 publications

Comparison of antioxidant and antimicrobial activities of two cultivated Cistus species from Tunisia

Comparison of antioxidant and antimicrobial activities of two cultivated Cistus species from Tunisia

Effet Antimycobactérien Des Plantes Marocaines: Revue Générale

A Review on Cistus sp.: Phytochemical and Antimicrobial Activities

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