Antimicrobials tethering on suture surface through a hydrogel: a novel strategy to combat postoperative wound infections

Kalita, Himadri; Hazarika, Ankita; Kalita, Sanjeeb; Kandimalla, Raghuram; Devi, Rajlakshmi

doi:10.1039/c7ra04888b

Cited by 9 publications

(7 citation statements)

References 41 publications

(40 reference statements)

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“…hydrogel and gum acacia (PRWSc). The study confirmed the antimicrobial activity (bacteria and fungi), the sustained release of the drugs from the suture and the biocompatibility towards mammalian cells and also inhibition of biofilm on PRWSc surface, which indicate its potential clinical use (H. Kalita et al, 2017).…”

Section: Bacteriasupporting

confidence: 66%

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Curcumin nanoformulations for antimicrobial and wound healing purposes

Salehi

Rodrigues

Peron

et al. 2021

Phytotherapy Research

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The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half‐life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.

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Section: Bacteriasupporting

confidence: 66%

“…Another biocompatible suture biomaterial study explored Eri silk waste (H. Kalita, Hazarika, Kalita, Kandimalla, & Devi, 2017). The suture was had antimicrobial agents‐growth factor cocktail in Aloe vera (L.) Burm.f.…”

Section: Pharmacological Properties Of Curcumin Nanoformulationsmentioning

confidence: 99%

Curcumin nanoformulations for antimicrobial and wound healing purposes

Salehi

Rodrigues

Peron

et al. 2021

Phytotherapy Research

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“…The presence of growth factor helps skin tissue regeneration by the formation of collagen fibers and epidermis in the wounded area. 17 The nerve growth factor triggers these tissue remodeling functions through the interaction between two classes of cell surface receptors, namely tropomyosin receptor kinase A and the neurotrophin receptor. 2 This could have resulted in the faster wound healing in the BSc sutured rats as observed in this study.…”

Section: Resultsmentioning

confidence: 99%

“…Suture materials were incubated with mammalian erythrocyte and its morphology was observed under FESEM. 17 after the incubation period (from the above experiment) the pellet of erythrocytes was collected and fixed in 3% glutaraldehyde for 4 h. The fixed cells were washed with 0.2 mM phosphate buffer saline (PBS) and incubated in PBS for 6 h. The incubated cells were subjected to an acetone dehydration process (30, 50, 70, 90, 95 and 100%) and finally treated with tetra methyl saline for 15 min to achieve complete dryness, the powdered erythrocytes were then observed under FESEM.…”

Section: Methodsmentioning

confidence: 99%

Development of banana (Musa balbisiana) pseudo stem fiber as a surgical bio-tool to avert post-operative wound infections

et al. 2018

Self Cite

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“…The success of the suggestion depends on the inferiority of the implied person. If the implied person is smarter than himself, he must accept his judgment, and then accept the influence of the implied person, and replace his thinking and judgment with the wisdom of others [11][12] . Of course, these psychological processes usually occur in the subconscious mind.…”

Section: Core Conceptsmentioning

confidence: 99%

Positive Psychological Suggestion Combined with Wet Dressing Treatment on Self-Efficacy of Chronic Wound Resection

2020

IJHPM

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The purpose of this article is to analyze the clinical manifestations and pathological mechanism of surgical chronic wounds, and to standardize the nursing management of wounds. The implementation of positive psychological suggestion interventions on surgical patients can alleviate the patients' unhealthy psychology such as psychological anxiety and depression, and explore how wet therapy can improve the healing rate of wounds. The method in this paper is to use a random sample control method to classify 70 eligible postoperative patients, establish a control group and an intervention group, the intervention group is given positive psychological suggestion combined with wet therapy, and the control group uses normal nursing methods. Statistical analysis of various data of chronic wound recovery was performed on the two groups of patients in the experiment to explore the actual effect of psychological suggestion combined with wet treatment. Corresponding conclusions are drawn through data comparison. The results of the study indicate that the differences in the specific pathological conditions of the wounds are not statistically significant. The cure rate of the intervention group was 71.6%, which was significantly higher than that of the control group, 35.8%. The difference between the two groups was statistically significant. The average wound healing time of the intervention group was (6.2 ± 1.9) d, which saved a lot of time compared with the control group's (13.5 ± 2.1) d. Therefore, the positive hint that combined wet therapy has the advantages of improving the cure rate, shortening the average healing time of wounds, shortening the average length of hospital stay, and reducing the pain during dressing change compared with conventional nursing methods. Improving postoperative recovery methods will not only shorten the recovery process, but also have a positive impact on the recovery of patients' self-efficacy.

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Antimicrobials tethering on suture surface through a hydrogel: a novel strategy to combat postoperative wound infections

Abstract: The present study aimed to develop a novel biocompatible suture biomaterial from Eri silk waste to avoid surgical site infections.

Cited by 9 publications

References 41 publications

Curcumin nanoformulations for antimicrobial and wound healing purposes

Curcumin nanoformulations for antimicrobial and wound healing purposes

Development of banana (Musa balbisiana) pseudo stem fiber as a surgical bio-tool to avert post-operative wound infections

Positive Psychological Suggestion Combined with Wet Dressing Treatment on Self-Efficacy of Chronic Wound Resection

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