Antimicrobial use for the management of varicella in Thailand: a retrospective observational study

Chokephaibulkit, Kulkanya; Samant, Salome; Chaisavaneeyakorn, Sujittra; Kamolratanakul, Supitcha; Limpadanai, Sujane; Kebede, Nehemiah; Stephens, Jennifer; Sukarom, Isaya; Pawaskar, Manjiri

doi:10.1080/03007995.2023.2200123

Cited by 1 publication

(4 citation statements)

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“…Half of the patients had mild disease (<50 skin lesions), 19 reported some varicella complication, and 10 (all of whom were children) were immunocompromised. Additional details on clinical characteristics are published elsewhere [ 26 ].…”

Section: Resultsmentioning

confidence: 99%

“…Almost all patients (95.8%) were prescribed at least 1 medication of any type. Overall, 20.8% of all patients were prescribed at least 1 antibiotic medication, and 46.5% were prescribed at least 1 antiviral medication (details published elsewhere) [ 26 ]. Adults were more likely to be prescribed at least 1 antiviral compared with children (96.7% vs 31.5%, P <0.001).…”

Section: Resultsmentioning

confidence: 99%

“…The mean cost of antivirals among those prescribed at least 1 antiviral was higher among pediatric patients than adults (12 USD vs 7 USD/383 THB vs 210 THB, P <0.001). Additional details on medication use are provided elsewhere [ 26 ].…”

Section: Resultsmentioning

confidence: 99%

“…Exclusion criteria for this study included a diagnosis of herpes zoster or prior varicella vaccination. Additional details on study design, clinical outcomes, and medication use are published elsewhere [ 26 ].…”

Section: Methodsmentioning

confidence: 99%

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Economic burden of varicella in Bangkok, Thailand: A multicenter medical chart review study

Samant,

Pawaskar,

Chaisavaneeyakorn

et al. 2024

PLOS Glob Public Health

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Our multicenter, medical chart review, cost-of-illness study used a micro-costing approach to evaluate the economic burden associated with varicella in Bangkok, Thailand, from a societal perspective. We reviewed medical charts of adults and children with a primary diagnosis of varicella (2014–2018) from 4 hospitals in Bangkok. Reported healthcare resource utilization and missed school or workdays were extracted from medical charts. Mean direct, indirect, and total costs per patient were estimated for overall, adult, and pediatric patients (2020 USD). Of the 200 children and 60 adults, 99.6%, 5.4%, and 5.4% had a varicella-related outpatient visit, emergency department visit, and hospitalization, respectively. The mean direct medical cost was 33 USD for pediatric and adult patients. The mean cost of outpatient visits (8 vs 13 USD, P<0.001) and medications (7 vs 9 USD, P<0.001) was significantly lower among pediatric patients. Forty-eight children reported a mean of 5.8 school days lost, and 32 adult patients reported a mean of 7.4 workdays lost. The mean total cost per varicella patient was 89 USD, with the mean total cost higher for adult than pediatric patients (145 vs 72 USD, P<0.001). Indirect cost accounted for 63% of the total cost per patient (54% for pediatric patients and 77% for adult patients). There is a substantial economic burden associated with patients seeking varicella-related healthcare in Thailand, including considerable indirect costs.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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