Antimicrobial textiles for sutures, implants, and scaffolds

Chen, X.; Guan, Yu-Xin; Wang, L.; Sanbhal, N.A.; Zhao, Fan; Zou, Qianda; Zhang, Q.

doi:10.1016/b978-0-08-100576-7.00014-6

Cited by 5 publications

(2 citation statements)

References 115 publications

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“…These textiles are also utilized to treat skin infections and to improve the longevity and durability of fabrics. Applications of antimicrobial fabrics differ in functions and mechanisms, but all these applications aim to prevent problems caused by harmful microorganisms (Chen et al 2016;Hui et al 2016;Laird and Riley 2016;Thilagavathi and Viju 2016).…”

Section: Introductionmentioning

confidence: 99%

Fabrication and Characterization of Electrospun Copper Oxide-Cellulose Acetate Microfiber Composite

Herrera¹,

Grande²,

Migo³

et al. 2021

Philipp J Sci

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Antimicrobial textiles are indispensable in medical applications. Improving these textiles through the use of fiber composites in their production can further advance its applications. Electrospinning is one of the most practical and efficient methods of producing fiber composites. This research dealt with the fabrication and characterization of electrospun copper oxidecellulose acetate (CuO/CA) microfiber composite. CuO loading, electrospinning applied voltage, and flow rate were varied following a central composite design (CCD). Their effects on the antibacterial activity and morphology of the microfiber composites were determined. The presence of the functional groups of CuO in the FTIR (Fourier transform infrared) spectrum of the composite proved the embedment of CuO in the microfiber. The fiber composite inhibited the growth of Staphylococcus aureus, but no antibacterial activity was observed against Escherichia coli. Statistical analysis showed that only the CuO loading has a significant effect on the antibacterial activity against S. aureus while applied voltage and flow rate have insignificant effects. Antibacterial activity has a direct relationship with CuO loading. The increase in CuO concentration increased the fiber diameter and reduced bead formation. Fiber diameter decreases and bead formation increases at increasing applied voltage. Increasing the flow rate increases bead formation and decreases fiber diameter.

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Section: Introductionmentioning

confidence: 99%

Fabrication and Characterization of Electrospun Copper Oxide-Cellulose Acetate Microfiber Composite

Herrera¹,

Grande²,

Migo³

et al. 2021

Philipp J Sci

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“…PCL is one of the most elastic among the synthetic bioresorbable polymers [14,15,16]. It is used in clinics as a surgical material, and its biomedical applications have been researched in controlled drug release applications and in long-term implants for vascular surgery [17,18,19]. PCL has a low glass transition temperature of about −60 °C, a low melting point of around 60 °C, and a high thermal stability.…”

Section: Introductionmentioning

confidence: 99%

Fabrication and Characterization of Bioresorbable Drug-coated Porous Scaffolds for Vascular Tissue Engineering

et al. 2019

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Bioresorbable polymers have been studied for several decades as attractive candidates for promoting the advancement of medical science and bio-technology in modern society. In particular, with a well-defined architecture, bioresorbable polymers have prominent advantages over their bulk counterparts for applications in biomedical and implant devices, such as cell delivery, scaffolds for tissue engineering, and hydrogels as well as in the pharmaceutical fields. Biocompatible implant devices based on bioresorbable materials (for instance, bioresorbable polymers that combine the unique advantages of biocompability and easy handling) have emerged as a highly active field due to their promising applications in artificial implant systems and biomedical devices. In this paper, we report an approach to fabricate porous polycaprolactone (PCL) scaffolds using a 3D printing system. And its surface was treated to a hydrophilic surface using plasma treatment. Then, the aspirin and atorvastatin calcium salt mixture was dip coated onto the surface. The drug coating technology was used to deposit the drug material onto the scaffold surface. Our porous PCL scaffold was coated with aspirin and atorvastatin calcium salt to reduce the blood LDL cholesterol and restenosis. These results suggest that our approach may provide a promising scaffold for developing bioresorbable drug-delivery-biomaterials. We further demonstrate that our bioresorbable medical device can be used as vascular scaffolds to provide a wide range of applications for the design of medical devices.

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Development of One‐Step Water‐Repellent and Flame‐Retardant Finishes for Cotton

Abdelrahman

Khattab

2019

ChemistrySelect

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Pyrovatex is a well-known commercial flame-retardant which is commonly applied for cotton fibers. Unfortunately, Pyrovatex has the concern of discharging toxic formaldehyde, and additionally it necessitates formaldehyde-based cross-linking agents to enhance the flame retardant character and durability. Thus, formaldehyde level is considerably increased in the treated cotton fabrics. Herein, we develop a simple approach toward superhydrophobic and flame-retardant coating for cotton fabrics. We apply one-bath pad-dry-cure technique in absence of formaldehyde which is usually applied as a cross-linker for the application and fixation of the Pyrovatex flame-retardant. Room temperature vulcanized (RTV) silicone was employed as a formaldehyde free cross-linking agent which allowed using Pyrovatex at lower concentration compared to commercial cross-linkers. The flame retardancy of the fabric was improved as a result of the higher bonding of Pyrovatex with both cotton fibers and RTV which in turn was bonded to cotton fibers too. Only 150 g/L of Pyrovatex with RTV silicone introduced much better flame retardant efficiency than applying 450-500 g/L of Pyrovatex ACS alone. Furthermore, RTV silicone further improved the water-repellent effect on the fabric surface. Washing properties of the treated cotton fabrics proved durability. The surface morphology and comfort properties of the treated cotton was explored.[a] Dr.

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Antimicrobial textiles for sutures, implants, and scaffolds

Cited by 5 publications

References 115 publications

Fabrication and Characterization of Electrospun Copper Oxide-Cellulose Acetate Microfiber Composite

Fabrication and Characterization of Electrospun Copper Oxide-Cellulose Acetate Microfiber Composite

Fabrication and Characterization of Bioresorbable Drug-coated Porous Scaffolds for Vascular Tissue Engineering

Development of One‐Step Water‐Repellent and Flame‐Retardant Finishes for Cotton

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