Antimicrobial susceptibility trends in Campylobacter jejuni and Campylobacter coli isolated from a rural Egyptian pediatric population with diarrhea

Putnam, Shannon D.; Frenck, Robert W.; Riddle, Mark S.; El-Gendy, Atef; Taha, Nancy N.; Pittner, Brian T.; Abu‐Elyazeed, Remon; Wierzba, Thomas F.; Rao, Malla R.; Savarino, Stephen J.; Clemens, John D.

doi:10.1016/s0732-8893(03)00154-8

Cited by 30 publications

(28 citation statements)

References 19 publications

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“…13,14 Interestingly, the age effect direction among military populations is different to what has been traditionally found in previous non-military cohort studies or among general travelers, where increased risk is associated with younger age and more adventurous travel (i.e., increased risk-taking behavior). 10,15 Prior history of diarrhea was also found to be a risk factor for developing diarrhea during the study. Plausible explanations could include differences in susceptibilities of individuals or risk behaviors.…”

Section: Discussionmentioning

confidence: 86%

“…is alarming and supports a continued trend to increasing resistance, which has been recently described among Campylobacter recovered in Egypt over recent years. 15 Self-reported diarrhea incidence was seven times more common than self-reported injury estimates and six times more common than acute respiratory illnesses, two of the most commonly reported health problems in the troops. Days lost were similar for diarrhea and non-combat injury (1.3 days per 100 person-months) and higher compared with respiratory illness (0.9 days per 100 person-months).…”

Section: Discussionmentioning

confidence: 98%

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A Prospective Study of Acute Diarrhea in a Cohort of United States Military Personnel on Deployment to the Multinational Force and Observers, Sinai, Egypt

Riddle

Rockabrand²,

Schlett³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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Abstract. To better understand the epidemiology of diarrhea in deployed personnel to the Middle East, a prospective cohort study of travelers' diarrhea (TD) was conducted between May 2004 and January 2005 at the Multinational Force and Observers (MFO) camp in the southern Sinai. A baseline entry questionnaire and stool specimen was provided on study entry, and volunteers were followed every 6 weeks. Of 211 volunteers, 145 (68.7%) completed one or more followup visits. In total, 416 follow-up surveys were completed, which described an overall incidence of 25.2 episodes per 100 person months (95% confidence interval = 21.2-30.0). Additionally, stools were collected in 72 of 77 diarrhea-associated clinic visits, with bacterial pathogens most commonly isolated (enterotoxigenic Escherichia coli in 30 [42%] samples and Campylobacter jejuni in 7 [10%] samples) Despite modern preventive methods, diarrhea is still a common problem for deployed US military personnel in Egypt, frequently resulting in diminished ability to work.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 98%

A Prospective Study of Acute Diarrhea in a Cohort of United States Military Personnel on Deployment to the Multinational Force and Observers, Sinai, Egypt

Riddle

Rockabrand²,

Schlett³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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“…Transmission of antimicrobial resistance from food animals to humans can occur via the food chain [126,133]. It is difficult to determine the precise extend of the risk posed to human health [127].…”

Section: Surveillance Of Antimicrobial Resistance In Campylobacter Sppmentioning

confidence: 99%

Campylobacter

et al. 2005

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-Species within the genus, Campylobacter, have emerged over the last three decades as significant clinical pathogens, particularly of human public health concern, where the majority of acute bacterial enteritis in the Western world is due to these organisms. Of particular concern are the species, C. jejuni and C. coli, which are responsible for most of these gastrointestinal-related infections. Although these organisms have already emerged as causative agents of zoonoses, several aspects of their epidemiology and pathophysiology are only beginning to emerge. Trends in increasing antibiotic resistance are beginning to emerge with oral antibiotics, which may be the drug of choice for when it is necessary to intervene chemotherapeutically. This review wishes to examine (i) emerging clinical aspects of the disease, such as Guillain Barré syndrome (GBS), (ii) the association between these organisms and poultry as a natural host, (iii) environmental aspects of Campylobacter epidemiology, (iv) the emergence of atypical campylobacters (v) emerging trends in antibiotic resistance, (vi) adoption of modern methods for the detection of campylobacters.

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“…High percentage (24.1%) of thermophilic Campylobacter strains resistant to erythromycin isolated from humans in developed countries is a surprising fact, having in mind a strict control of antibiotic use in human and veterinary medicine in these countries. In some countries, for example Chile and Egypt, have not documented the resistance to erythromycin in strains isolated from humans (Fernández et al, 2000;Putnam et al, 2003). Lower level of resistance to erythromycin, ranging from 3.4 to 9.1% was reported by authors from Australia, India, USA, Brasil and Belgium (Alfredson et al, 2003;Aquino et al, 2002;Gupta et al, 2004;Jain et al, 2005;Vlieghe et al, 2008).…”

Section: Resultsmentioning

confidence: 99%

“…Intestinal campylobacteriosis in humans is the result of infection due to thermophilic Campylobacter spp., mostly Campylobacter jejuni and Campylobacter coli, resulting in 400 million bacterial intestinal infections around the world every year (Putnam et al, 2003;Zimmer et al, 2003). A very important factor in intestinal campylobacteriosis development is a very low infective doses of only 500 bacteria (Walker et al, 1986).…”

Section: Introductionmentioning

confidence: 99%

Resistance to erythromycin of Campylobacter jejuni and Campylobacter coli isolated from animals and humans

Tambur¹,

Miljković-Selimović²,

Kulišić³

et al. 2011

Afr. J. Pharm. Pharmacol.

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The sensititivity of thermophilic Campylobacter strains isolated from caecum of broiler chickens as well as caecum and colon of pigs and human stools, were tested against erythromycin. In 16 strains isolated in broiler chickens, resistance rate was found to be 12.50%. Three of 10 strains of Campylobacter jejuni and one of 6 strains of Campylobacter coli isolated from broiler chickens were resistant to erythromycin. In 15 strains of thermophilic Campylobacters isolated from pigs, resistance rate to erythromycin was 40.00%. Resistance was exhibited more often in C. coli (50.00%) as compared to C. jejuni (20.00%). In 24 strains isolated from humans, resistance was demonstrated at the rate of 12.50%. Out of 17 strains of C. jejuni isolated from humans, resistance was exhibited in 17.65% strains. None of 7 strains of C. coli isolated from humans exhibited resistance to erythromycin. Thermophilic campylobacters, especially C. coli isolated from pigs were more resistant to erythromycin than strains isolated from humans and broiler chickens. Therefore, a great attention should be directed to the macrolides monitoring in swine farming in order to prevent resistance in animals and its subsequent spread to human.

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Antimicrobial susceptibility trends in Campylobacter jejuni and Campylobacter coli isolated from a rural Egyptian pediatric population with diarrhea

Cited by 30 publications

References 19 publications

A Prospective Study of Acute Diarrhea in a Cohort of United States Military Personnel on Deployment to the Multinational Force and Observers, Sinai, Egypt

A Prospective Study of Acute Diarrhea in a Cohort of United States Military Personnel on Deployment to the Multinational Force and Observers, Sinai, Egypt

Campylobacter

Resistance to erythromycin of Campylobacter jejuni and Campylobacter coli isolated from animals and humans

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