Antimicrobial Susceptibility Patterns of Escherichia Coli From Various Clinical Sources

Abstract

Escherichia coli is the major organism causing the urinary tract infection, wound infection and respiratory tract infection. A total of 2376 samples of urine, wound swab and sputum were analyzed for identification of bacterial isolates and their antimicrobial susceptibility pattern.

Changing Antimicrobial Susceptibility Pattern of E. coli Isolated from Urine and Pus Samples

“…16 (22) 55 (75) 69 (95) 62 (85) 21 (29) 21 (29) 34 (47) 65 (89) 16 (22) 16 (22) 16 (22) 16 (22) 33 (45) 26 (36) 16 (22) 45 62 (76) 10 (48) Total (28) 4 (14) 12 (43) 21 (75) 25 (89) 10 (36) 10 (36) 12 (43) 8 (29) 8 (29) 8 (29) 8 (29) 14 (50) 10 (36) 8 (29) 21 (75) 13 (46) 20 (71) 13 (46) AMP -AMPICILLIN, AMC -AMOXYCLAV, G -GENTAMYCIN, AK -AMIKACIN, CIP -CIPROFLOXACIN, NX -NORFLOXACIN, COT -COTRIMOXAZOLE, CAZ -CEFTAZIDIME, CTR -CEFTRIAXONE, CTX -CEFOTAXIME, CXM -CEFUROXIME, CN -CEFOXITIN, CPM -CEFIPIME, AT -AZTREONAM, MRP -MEROPENEM, PI -PIPERACILLIN, C -CHLORAMPHENICOL, TE -TETRACYCLINE Since standard medication with nitrofurantoin does not achieve therapeutic concentrations in the bloodstream, its use is advised only for complicated cystitis (Gautam et al, 2013). Most isolates were resistant to beta lactum antibiotics like ampicillin and cephalosporins.…”

“…E. coli is a common inhabitant of the human and animal gut, but can also be found in water, soil and vegetation (Kibret et al, 2011). It is the leading pathogen causing urinary tract infections and is among the most common pathogens causing blood stream infections, wound infection, otitis media and other complications in humans (Gautam et al, 2013).…”

Prevalence of multidrug resistant bacteria in causing community acquired urinary tract infection among the patients attending outpatient department of Seti Zonal Hospital, Dhangadi, Nepal

“…Similar findings were obtained in the study done by Tuladhar et al [16] in a hospital in Kathmandu, where MDR bacterial strains were detected in 35.21% with the most predominant MDR bacterium being E. coli followed by Klebsiella spp. Increasing haphazard use of antibiotics and sales of substandard drugs are responsible for development of multi drug resistance among the bacteria [17]. Due to development of drug resistance against commonly used antibiotics among the bacteria the therapeutic options have become limited.…”

Prevalence of Aerobic Gram-Negative Bacilli in Lower Respiratory Tract Infections in Menoufia Governorate, Egypt

“…Other studies; Gautam et al, (2013) recorded that 65.7% of E coli were resistant to ceftriaxone and none of them was resistant to imipenem. Patel et al, (2012) recorded that 13.2% of Pseudomonas spp.…”