Antimicrobial susceptibility of Haemophilus influenzae, Neisseria meningitidis and Streptococcus pneumoniae isolates causing meningitis in The Netherlands, 1993-1994

Enting, Roeline; Spanjaard, Lodewijk; Beek, Diederik van de; Hensen, E F; Gans, Jan de; Dankert, J.

doi:10.1093/jac/38.5.777

Cited by 20 publications

(17 citation statements)

References 22 publications

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“…This change was made because of the participation of centers in countries where highly resistant pneumococcal strains are more common than they are in the Netherlands. 10 …”

Section: Discussionmentioning

confidence: 99%

“…Similar rates were found in nationwide studies in the Netherlands. 10,11 In a prospective audit of empirical therapy in adults with bacterial meningitis in the Netherlands, monotherapy with amoxicillin or penicillin appeared to be prescribed most frequently. 11 Although dexamethasone is not associated with adverse events, concern has been expressed that because the drug reduces blood-brain permeability, it may impede the penetration of vancomycin into the subarachnoid space.…”

Section: Discussionmentioning

confidence: 99%

“…This regimen was based on the available data on susceptibility to antibiotics of cerebrospinal fluid isolates in the Netherlands. 10 The initial antibiotic treatment was maintained or changed according to the results of Gram's staining of cerebrospinal fluid.…”

Section: Treatmentmentioning

confidence: 99%

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Dexamethasone in Adults with Bacterial Meningitis

2002

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“…This change was made because of the participation of centers in countries where highly resistant pneumococcal strains are more common than they are in the Netherlands. 10 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Dexamethasone in Adults with Bacterial Meningitis

2002

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“…Antibiotic resistance rates among respiratory pathogens in The Netherlands are still quite low, although only limited data from the general population or from patients with meningitis (9,12) are available. The prevalence of beta-lactamase production among H. influenzae isolates from sputum samples taken in The Netherlands was only 6.3% in a recent study (21); these samples originate mainly from elderly patients with chronic pulmonary diseases.…”

mentioning

confidence: 99%

Nasopharyngeal Carriage of Potential Bacterial Pathogens Related to Day Care Attendance, with Special Reference to the Molecular Epidemiology of Haemophilus influenzae

Peerbooms

Engelen²,

Stokman³

et al. 2002

J Clin Microbiol

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Nasopharyngeal carriage of Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was studied in 259 children attending day care centers (DCC) in Amsterdam, The Netherlands, and in 276 control children. The DCC children were sampled a second time after 4 weeks. Carriage rates for DCC children and controls were 58 and 37% for S. pneumoniae, 37 and 11% for H. influenzae, and 80 and 48% for M. catarrhalis, respectively. No increased antibiotic resistance rates were found in strains isolated from DCC children. All H. influenzae isolates were typed by random amplified polymorphic DNA (RAPD) analysis. Evidence for frequent transmission of H. influenzae strains within DCC was found. In the control group only two isolates (4%) displayed identical RAPD types versus 38% of strains from DCC children. Colonization with H. influenzae appeared to be short-lived in these children; more than half of the children harboring H. influenzae in the first sample were negative in the second sample, whereas most children still positive in the second sample had a different genotype than in the first sample. Of the newly acquired strains in the second sample, 40% were identical to a strain that had been found in a child in the same DCC in the first sample. DCC are to be considered epidemiological niches with a high potential for the spread of pathogenic microorganisms.

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“…The isolates with reduced sensitivity to penicillin in the present study exhibited values between 0.125 and 1 mg/l with the MIC 50 and MIC 90 of 0.25 mg/ l and 0.5 mg/l respectively. In the Netherlands, 1,125 meningococcal strains isolated from blood or CSF were studied and the prevalence of intermediate penicillin-resistance meningococci was 3.3% (Enting et al 1996). Sáez Nieto et al (1997) described an increase of meningococcal strains showing MICs between 0.12 and 1 mg/l from 0.4% in 1985 and reaching 42.6% in 1990.…”

mentioning

confidence: 99%