Antimicrobial susceptibility and serogroups of Salmonella isolates from Riyadh, Saudi Arabia

Kambal, Abdelmageed M.

doi:10.1016/s0924-8579(96)00336-6

Cited by 10 publications

(15 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is in sharp contrast to the previous report from the same institution where serotypes B and C were reported to be the most commonly detected serotypes [20]. Similarly, the prevalence rate of S. enterica serotype Typhi in the present study was only 2% compared to a previous report from the southern region of the Kingdom of Saudi Arabia where S. enterica serotype Typhi constituted 65% of the isolates [21].…”

Section: Discussioncontrasting

confidence: 99%

“…Outbreaks of strains of S. enterica serotype Typhi resistant to all first-line drugs have been reported from the Indian subcontinent, Mexico, South Africa, and the Arabian Gulf [7,8,10,[20][21][22]. Similarly, nontyphoidal Salmonella strains resistant to the conventional first-line drugs have also been reported [14].…”

Section: Discussionmentioning

confidence: 99%

“…Although there are reports documenting infections with Salmonella spp. resistant to nalidixic acid in the Kingdom of Saudi Arabia [20,40,41], large-scale prevalence studies are recommended to investigate the current status of Salmonella infections and their susceptibility patterns in the community.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Salmonella isolates’ serotypes and susceptibility to commonly used drugs at a tertiary care hospital in Riyadh, Saudi Arabia

Somily

Sayyed

Habib

et al. 2011

J Infect Dev Ctries

View full text Add to dashboard Cite

Introduction: Resistance of Salmonella to therapeutic agents currently being used for treatment of Salmonella infections is emerging as a global problem. This study aimed to assess the prevalence of Salmonella serotypes and their susceptibility patterns to commonly used drugs for treatment of Salmonella infections including quinolones. Correlation between nalidixic acid susceptibility of these isolates and their ciprofloxacin minimum inhibitory concentrations was also sought. Methodology; Salmonella isolates (n=213) were collected between January 2007 and May 2009 at King Khalid University Hospital in Riyadh, Saudi Arabia. The isolates were serotyped and their susceptibilities to commonly used first-line anti-Salmonella drugs (ampicillin, ceftriaxone, trimethoprim/sulfamethoxazole, nalidixic acid and ciprofloxacin) were determined using the automated Microscan system, the Kirby-Bauer disk diffusion method, and E-test. Results: The most frequently detected serotype was D 1 (37%) followed by the serotypes, B (24%) and C 1 (11%). Non-typable Salmonella isolates detected using available conventional Salmonella anti-sera were (11%). Overall resistance rates to nalidixic acid, ampicillin, trimethoprim/sulfamethoxazole and ceftriaxone were 99/213 (46%), 43/213 (20%), 34/213 (16%) and 7/213 (3%), respectively. Of the total isolates, 117 (55%) had a ciprofloxacin MIC of <0.125 µg/ml and among these 105 (90%) were susceptible to nalidixic acid. The remaining 96 (45%) isolates had a ciprofloxacin MIC of ≥0.125 µg/ml and among them, 83 (86.5%) were resistant to nalidixic acid. Conclusions: The majority of Salmonella isolates in this study were non-typhi serotypes. Significantly higher proportions of Salmonellae were resistant to nalidixic acid and ciprofloxacin and a vast majority of nalidixic acid resistant organisms exhibited decreased susceptibility to ciprofloxacin.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Salmonella isolates’ serotypes and susceptibility to commonly used drugs at a tertiary care hospital in Riyadh, Saudi Arabia

Somily

Sayyed

Habib

et al. 2011

J Infect Dev Ctries

View full text Add to dashboard Cite

show abstract

“…No significant relationship between the ages and the isolated serotypes implicated in both typhoidal and non-typhoidal salmonellosis as p>0.05. This trend appears in agreement with the results of similar studies from Saudi Arabia (Kambal, 1996) and Hong Kong (Ling et al, 1991). However, the present study shows a much higher than usual proportion of the isolates from children when compared with that of Saudi Arabia where the prevalence was 60 and 40% in children and adults, respectively (Kambal, 1996).…”

Section: Discussionsupporting

confidence: 92%

Antibiotics susceptibility patterns and characterization of clinical Salmonella serotypes in Katsina State, Nigeria

Abdullahi¹,

K²,

Wartu³

et al. 2014

Afr. J. Microbiol. Res.

View full text Add to dashboard Cite

Serotyping characterization and antimicrobial susceptibility of Salmonella clinical isolates were examined for a period of 10-months to study the most frequently encountered serovars in salmonellosis and their antimicrobial susceptibility patterns. Seven hundred and twenty (720) samples of both stool and blood specimens were collected from out patients attending three hospitals in Katsina State, Nigeria. The samples were collected from patients diagnosed by clinicians with either pyrexia, gastroenteritis or both. Samples were cultured; isolates were identified and antibiotic susceptibility test was performed using standard procedures. The total number of 108 (15%) of the 720 samples collected yielded positive for Salmonella strains. Out of the 108 isolates, 61 (56.5%) were responsible for typhoidal salmonellosis, while 47(43.5%) were responsible for non-typhoidal salmonellosis. Of the 108 cases of salmonellosis, 91(84.3%) were from children and 17(15.7%) from adults. S. Typhi (40.7%) was the most frequently encountered, followed by S. Enteritidis (26.9%) and least encountered was S. Arizonae (2.8%). There was no significant difference in the serotypes isolated from each of the hospitals with respect to the type of salmonellosis caused with their p values > 0.05. Of the total isolates, 94.2% were found to be resistant to ampicillin, 22.2% resistant to cefotaxime, 72.8% resistant to chloramphenicol, 31.8% resistant to co-trimoxazole and 4.9% resistant to nalidixic acid. However, resistance to ofloxacin and ciprofloxacin by the isolates were not found. Therefore, ofloxacin and ciprofloxacin remains the drug of choice for severe cases of salmonellosis, although caution should be exercised by clinicians in their prescriptions such that fluoroquinolones antibiotic therapy is used only in laboratory-proven cases of typhoid fever and Salmonella-associated bacteraemia to preserve its efficacy.

show abstract

“…Although variable sensitivity with chloramphenicol was observed against isolates form both sources, however, the low resistance rate might be attributed to the controlled use of chloramphenicol due to the concern of its severe side effects which indirectly increases the efficiency of the antibiotic (Kambal, 1996;Learn-Han et al, 2009).The occurrence of multi-drug resistance Salmonella from fresh vegetables is of global health concern as this could led to major healthcare challenge since multi-drug resistance hinder the possibility of therapeutic treatments. The health benefits of consumption of vegetables has led to significant rise of eating of vegetables among the pregnant, young, old, and ill challenged individuals thereby leading to higher risk of infection among these group of consumers.…”

Section: Resultsmentioning

confidence: 99%

Biofilm formation of <i>Salmonella</i> species isolated from fresh cabbage and spinach

Isoken¹

2015

Journal of Applied Sciences and Environmental Management

View full text Add to dashboard Cite

ABSTRACT:The aim of the study was to isolate Salmonella from fresh cabbage and spinach vegetables, determine antimicrobial resistance and biofilm formation of the isolates. Spinach and cabbage farm vegetables were found to harbour Salmonella. A total of eighty-two Salmonella isolates were recovered from both vegetables and subjected to antimicrobial reactions. Salmonella isolate showed sensitivity against the aminoglycoside and quinolones.Isolates from cabbage showed ≥ 80% susceptibility to nalidixic acid and ciprofloxacin and an average of 72% susceptibility was exhibited against gentamicin and ofloxacin. Also, isolates from spinach vegetable demonstrated excellent sensitivity against chloramphenicol (94%), nalidixic acid (90%) and ofloxacin (82%). Variable resistant patterns was observed for tetracycline (58%: 47%), ampicillin (55.5%: 31.4%), erythromycin (58.1%: 62.7%), streptomycin (64.5%: 76.5%), cephalothin (35.5%: 39.2%) against isolates from cabbage and spinach respectively. The assessment of biofilm formation by Salmonella on microtitre plate showed that all Salmonella isolates were able to form biofilms. Isolates from cabbage were mainly strong producer 15(48.3%), while 11(35.5%) of the isolates were moderate producers and 6(16.1%) weak producer. On the other hand, 28(54.9%) of Salmonella isolates from spinach vegetable were moderate producer, 12(23.5%) weak producer and 11(21.5%) strong producer. The finding of this study shows that cabbage and spinach is potential host for the transmission of Salmonella to humans or other animals. The ability of the isolates to form biofilm reveals the potential of the isolates to persist on the vegetable and the pathogenic status of the isolates as well as ability to resist antimicrobial chemotherapy. © JASEM http://dx

show abstract

Antimicrobial susceptibility and serogroups of Salmonella isolates from Riyadh, Saudi Arabia

Cited by 10 publications

References 12 publications

Salmonella isolates’ serotypes and susceptibility to commonly used drugs at a tertiary care hospital in Riyadh, Saudi Arabia

Salmonella isolates’ serotypes and susceptibility to commonly used drugs at a tertiary care hospital in Riyadh, Saudi Arabia

Antibiotics susceptibility patterns and characterization of clinical Salmonella serotypes in Katsina State, Nigeria

Biofilm formation of <i>Salmonella</i> species isolated from fresh cabbage and spinach

Contact Info

Product

Resources

About