Antimicrobial susceptibility and pathogenic genes of<i>Staphylococcus aureus</i>isolated from the oral cavity of patients with periodontitis

Kim, Ga Yeon; Lee, Chong Heon

doi:10.5051/jpis.2015.45.6.223

Cited by 39 publications

(33 citation statements)

References 19 publications

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“…All 30 coagulase positive isolates of S. aureus were subjected to antibiotic susceptibility test and the results revealed that 93.33% isolates were found resistant to penicillin followed by 90% to amoxicillin, 83.33% to ampicillin and 33.33% to erythromycin where 80% sensitive to cephradine, 63.33% to ciprofloxacin, and 60% to erythromycin (53.33%) ( Table 3). Kim and Lee (2015) reported that S. aureus isolated from the periodontal patients showed 88% (36/41) isolates resistant to penicillin and ampicillin which is comparable to the present study. They also observed the susceptibility rate and found 98% isolates susceptible to cefotetan, 95% to ciprofloxacin and 90% to tetracycline and erythromycin that is comparatively higher than the current study.…”

Section: Resultssupporting

confidence: 90%

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Characterization of Staphylococcus aureus isolated from human dental infection

Das¹,

Sabuj²,

Haque³

et al. 2019

Afr. J. Microbiol. Res.

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Staphylococcus aureus is an opportunistic pathogen causing dental infection and systemic infections in human body. This organism decreases susceptibility to several types of antibiotics every day and becomes more resistant which is a growing sense of concern in this era. Considering this fact, the study was attempted to characterize the S. aureus from human dental infection and to determine the antibiogram profile of isolates. Sixty four (64) samples were collected from the patients with dental infection who visited different dental clinics and hospitals in Mymensingh, Bangladesh for treatment. Isolation and identification of S. aureus were conducted by using cultural, morphological, and biochemical characteristics. Polymerase chain reaction was performed for final confirmation of S. aureus followed by detection of methicillin resistant S. aureus (MRSA) targeting mecA and mecC genes. Antibiotic susceptibility test of isolated bacteria was tested against seven antibiotics by disk diffusion methods. Forty isolates among 64 samples were found positive for S. aureus based on cultural characteristics. Among them 30 isolates were found positive in coagulase test. Depending on the result of coagulase test, all the 30 isolates were subjected to antibiotic sensitivity test and among them 25 were 100% resistant to penicillin, ampicillin and amoxicillin. All the 25 isolates were subjected to polymerase chain reaction (PCR) to identify methicillin resistant gene mecA and mecC. Eight isolates were positive for mecA gene while no isolates were positive for mecC. The present findings conclude that S. aureus is prevalent in dental infections and contain methicillin resistant genes.

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Section: Resultssupporting

confidence: 90%

“…The percentage of S. aureus isolated from human dental infection is more frequent as the findings of Ohara-Nemoto et al 2008reported 46.4%. McCormack et al (2015) and Kim and Lee (2015) reported 18 and 36.6% S. aureus in human oral and perioral infections that is comparatively lower than the current results.…”

Section: Resultscontrasting

confidence: 87%

Characterization of Staphylococcus aureus isolated from human dental infection

Das¹,

Sabuj²,

Haque³

et al. 2019

Afr. J. Microbiol. Res.

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“…S. aureus is often carried within the nares and on the skin of colonized hosts. Although S. aureus is generally thought to be a noncommensal, increasing numbers of culture and molecular-based studies have shown that this pathogenic species is more common on mucosal surfaces from healthy subjects than originally hypothesized (87)(88)(89)(90)(91)(92)(93)(94)(95)(96)(97). While this pathogen may not directly contribute to localized mucosal virulence in the oral cavity, the transient or persistent carriage of S. aureus on various mucosal surfaces can provide an infectious source for systemic disease, particularly when C. albicans is present (…”

Section: Candida-mycobacterium Tuberculosismentioning

confidence: 99%

Candida–Bacteria Interactions: Their Impact on Human Disease

et al. 2016

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Candida species are the most common infectious fungal species in humans; out of the approximately 150 known species, Candida albicans is the leading pathogenic species, largely affecting immunocompromised individuals. Apart from its role as the primary etiology for various types of candidiasis, C. albicans is known to contribute to polymicrobial infections. Polymicrobial interactions, particularly between C. albicans and bacterial species, have gained recent interest in which polymicrobial biofilm virulence mechanisms have been studied including adhesion, invasion, quorum sensing, and development of antimicrobial resistance. These trans-kingdom interactions, either synergistic or antagonistic, may help modulate the virulence and pathogenicity of both Candida and bacteria while uniquely impacting the pathogen-host immune response. As antibiotic and antifungal resistance increases, there is a great need to explore the intermicrobial cross-talk with a focus on the treatment of Candida-associated polymicrobial infections. This article explores the current literature on the interactions between Candida and clinically important bacteria and evaluates these interactions in the context of pathogenesis, diagnosis, and disease management.

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“…Enterococcus faecalis, on the other hand, plays a pivotal role in establishing a microbial community by connecting various bacteria in the oral cavity [5][6][7] . Staphylococcus aureus, a Gram-positive staphylococcus typically found in the respiratory system, on the skin, and in the oral cavity, is also found in the periodontium where it may cause periodontal disease 8,9) . Candida albicans, the most common fungus in the oral cavity and the gastrointestinal tract, causes opportunistic infections by quickly expanding due to host environmental changes induced by various factors 10,11) .…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity of Korean Propolis Extracts on Oral Pathogenic Microorganisms

Roh

Kim

2018

J Dent Hyg Sci

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Propolis has been used as a natural remedy in folk medicine worldwide. The antibacterial, antiviral, antifungal, and antiprotozoal aspects of its antimicrobial properties have been widely investigated. However, few studies focused on its applications in dentistry. Many dental diseases are related to various microorganisms in the oral cavity. In this study, we assessed the antimicrobial activity of Korean propolis extract, collected from 6 different regions, on oral pathogenic microorganisms. The propolis samples, collected from 6 different regions (P1: Uijeongbu, P2: Ansan, P3: Hongcheon, P4: Iksan, P5: Gwangju, and P6: Sangju), were dissolved in ethanol at two different concentrations (10 and 50 mg/ml). Three oral bacteria (Streptococcus mutans, Staphylococcus aureus, and Enterococcus faecalis) and one fungus (Candida albicans) were activated in general broth for 24 hours. Microorganisms were diluted and spread onto agar plates, onto which sterilized 6 mm filter papers with or without each propolis sample were placed. After 24 hours of incubation, clear zones of inhibition were observed. All tests were performed in triplicate. The propolis samples showed significant antibacterial and antifungal activity on oral pathogenic microorganisms; in addition, low-concentration groups showed outstanding antimicrobial efficacy on the 4 different microorganisms. Among the samples, P6 had significantly higher antibacterial activity than that of the others against three different bacteria. In particular, a high concentration of P6 showed a significant antifungal effect. In conclusion, we confirmed that Korean propolis has an inhibitory effect on oral pathogenic bacteria and fungi. Therefore, we suggest the possibility of developing oral medicine and oral care products based on Korean propolis.

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Antimicrobial susceptibility and pathogenic genes ofStaphylococcus aureusisolated from the oral cavity of patients with periodontitis

Cited by 39 publications

References 19 publications

Characterization of Staphylococcus aureus isolated from human dental infection

Characterization of Staphylococcus aureus isolated from human dental infection

Candida–Bacteria Interactions: Their Impact on Human Disease

Antimicrobial Activity of Korean Propolis Extracts on Oral Pathogenic Microorganisms

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