Antimicrobial susceptibilities of Pasteurella strains isolated from humans

Lion, C.; Conroy, M. C.; Carpentier, A.M.; Lozniewski, Alain

doi:10.1016/j.ijantimicag.2006.02.004

Cited by 38 publications

(30 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Treatment for infections with P. multocida commonly includes broad-spectrum antimicrobials (5,25,26). The findings of our antibiotic susceptibility studies, like the findings of Kehrenberg et al (25) in France, Salmon et al (32) in North America, and Yoshimura et al (38) in Japan, indicated that cephalosporins (cefazolin, ceftiofur), florfenicol, and fluoroquinolones (ciprofloxacin) were the most active drugs.…”

Section: Discussionsupporting

confidence: 79%

“…Although antimicrobial therapy is a widely available tool for the prevention and control of clinical infections (5,25,26), antibiotic resistance in pathogenic bacteria from food-producing animals and environmental sources is recognized as a global problem for public health (6,37). Over the past decade, the high degree of resistance to common antibiotics and the worldwide emergence of multidrug resistant phenotypes have become of increasing concern (8,36,37).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Isolation, Antimicrobial Resistance, and Virulence Genes of Pasteurella multocida Strains from Swine in China

et al. 2009

View full text Add to dashboard Cite

A total of 233 isolates of Pasteurella multocida were obtained from 2,912 cases of clinical respiratory disease in pigs in China, giving an isolation rate of 8.0%. Serogroup A P. multocida isolates were isolated from 92 cases (39.5%), and serogroup D isolates were isolated from 128 cases (54.9%); 12 isolates (5.2%) were untypeable. P. multocida was the fourth most frequent pathogenic bacterium recovered from the respiratory tract, after Streptococcus suis, Haemophilus parasuis, and Escherichia coli. All isolates were characterized for their susceptibilities to 20 antibiotics and the presence of 19 genes for virulence factors (VFs). The frequency of antimicrobial resistance among P. multocida isolates from swine in China was higher than that reported among P. multocida isolates from swine in from other countries, and 93.1% of the isolates showed multiple-drug resistance. There was a progressive increase in the rate of multiresistance to more than seven antibiotics, from 16.2% in 2003 to 62.8% in 2007. The resistance profiles suggested that cephalosporins, florfenicol, and fluoroquinolones were the drugs most likely to be active against P. multocida. Use of PCR showed that colonization factors (ptfA, fimA, and hsf-2), iron acquisition factors, sialidases (nanH), and outer membrane proteins occurred in most porcine strains. The VFs pfhA, tadD, toxA, and pmHAS were each present in <50% of strains. The various VFs exhibited distinctive associations with serogroups: concentrated in serogroup A, concentrated in serogroup D, or occurring jointly in serogroups A and D. These findings provide novel insights into the epidemiological characteristics of porcine P. multocida isolates and suggest that the potential threat of such multiresistant bacteria in food-producing animals should not be neglected.

show abstract

Section: Discussionsupporting

confidence: 79%

mentioning

confidence: 99%

Isolation, Antimicrobial Resistance, and Virulence Genes of Pasteurella multocida Strains from Swine in China

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Other options are cephalosporins, tetracyclines, fluoroquinolones, macrolides, and trimethoprimsulfamethoxazole [1,8]. The strain we identified was susceptible to all of these antibiotics.…”

Section: Case Reportmentioning

confidence: 99%

Acute Cholecystitis with Bacteremia Caused by Pasteurella multocida

Nagata

Yamada

Uramaru

et al. 2014

Surgical Infections

View full text Add to dashboard Cite

show abstract

“…Therefore, antimicrobial treatments remain an important weapon in combating infections caused by this pathogen. Although antimicrobial therapy is widely available for the prevention and control of clinical infections [6,9], the rising number of antibiotic resistant isolates is a growing global health concern for both human and animal populations [3,15]. Over the past decade, high resistance levels to commonly used antibiotics and the worldwide emergence of multidrug resistant (MDR) phenotypes have become of increasing concern [4,15].…”

mentioning

confidence: 99%

Antimicrobial Susceptibility and PFGE Genotyping of Haemophilus parasuis Isolates from Pigs in South China (2008-2010)

Zhang

Zhao

et al. 2011

J. Vet. Med. Sci.

View full text Add to dashboard Cite

ABSTRACT. H. parasuis isolates (n=112) from pigs were tested for antimicrobial susceptibility against 23 antimicrobial agents by the disk diffusion method. All isolates were sensitive to Florfenico and most strains were sensitive to Cefotaxime (103/112; 92%), Ceftazidime (99/112; 88.4%), Chloramphenicol (90/112; 80.4%) and Gentamicin (85/112; 75.9%). High resistance levels to Nalidixic acid (84.8%), TMP (67.9%) and Trimethoprim+Sulfamethoxazole (58%) were observed. Genomic DNA extracted from 52 isolates resistant to at least seven antimicrobial agents was analyzed by PFGE and 46 distinct PFGE patterns identified. Diverse variation was observed between the drug-resistant H. parasuis isolates examined, suggesting that resistance traits were acquired independently by the respective isolates.KEY WORDS: antimicrobial susceptibility, Haemophilus parasuis, PFGE, swine.

show abstract

Antimicrobial susceptibilities of Pasteurella strains isolated from humans

Cited by 38 publications

References 18 publications

Isolation, Antimicrobial Resistance, and Virulence Genes of Pasteurella multocida Strains from Swine in China

Isolation, Antimicrobial Resistance, and Virulence Genes of Pasteurella multocida Strains from Swine in China

Acute Cholecystitis with Bacteremia Caused by Pasteurella multocida

Antimicrobial Susceptibility and PFGE Genotyping of Haemophilus parasuis Isolates from Pigs in South China (2008-2010)

Contact Info

Product

Resources

About