Antimicrobial Silver Nitrate-doped Polyvinyl Chloride Cast Films: Influence of Solvent on Morphology and Mechanical Properties

Merchan, Martha; Sedlaříková, Jana; Vesel, Alenka; Machovský, Michal; Sedlařík, Vladimír; Sáha, Petr

doi:10.1080/00914037.2012.670821

Cited by 10 publications

(10 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One of the promising solutions to this problem is the incorporation of antimicrobial agents into the polymer matrix. 3 Antimicrobial agents of low molecular weight are used for the sterilization of water and as antimicrobial drugs as food preservatives and for soil sterilization. 4 However, they can have the limitation of residual toxicity even when suitable amounts of the agents are added.…”

Section: Introductionmentioning

confidence: 99%

Cinchonidinyl-Based Acrylic and Methacrylic Homopolymers: Synthesis, Characterization, and Antibacterial Activity

Kumar

Mageswari

Nithya

et al. 2015

Adv. Polym. Technol.

View full text Add to dashboard Cite

ABSTRACT:The monomers (5-ethenyl-1-azabicyclo [2.2.2] octan-2-yl)-quinolin-4-ylmethyl acrylate (EAOQMA) and (5-ethenyl-1-azabicyclo [2.2.2] octan-2-yl)-quinolin-4-ylmethyl methacrylate (EAOQMMA) were synthesized by reacting (5-ethenyl-1-azabicyclo octan-2-yl)-quinolin-4-ylmethanol [cinchonidine] with acryloylchloride and methacryloyl chloride, respectively, in the presence of triethylamine. The homopolymers were synthesized by the free radical polymerization in tetrahydrofuran at 70 ± 2°C in nitrogen atmosphere using 2,2 -azobisisobutyronitrile as an initiator. The monomers and homopolymers were characterized by UltraViolet (UV), Fourier transform infrared, Proton-Nuclear Magnetic Resonance ( 1 H NMR), and Carbon-13 Nuclear Magnetic Resonance ( 13 C NMR) spectroscopic techniques. The glass transition temperature (T g ,°C) was determined by differential scanning calorimetry. The thermal stability of the poly(EAOQMMA) was performed by thermogravimetric analysis, which showed higher thermal stability of about 706°C than that of poly(EAOQMA). The antibacterial activity of monomers and polymers has been evaluated by determining the inhibitory zone diameters against Gram-positive bacteria (Staphylococcus aureus) and Gram-negative bacteria (Pseudomonas aeruginosa), in which cinchonidine acrylate and Cinchonidine methacrylate homopolymer showed better activity than their corresponding monomers. Surface morphology of the monomers and polymers were examined by Scanning Electron Microscope (SEM) analysis. C

show abstract

Section: Introductionmentioning

confidence: 99%

Cinchonidinyl-Based Acrylic and Methacrylic Homopolymers: Synthesis, Characterization, and Antibacterial Activity

Kumar

Mageswari

Nithya

et al. 2015

Adv. Polym. Technol.

View full text Add to dashboard Cite

show abstract

“…One of the most important classes of medical devices are catheters, which can be used as diagnostic tools and also as clinical tools [1]. Catheters are used in treating vascular diseases and can also provide fluid administration, parenteral nutrition, hemodynamic monitoring, blood sampling, and administration of drugs [2,3,4,5,6,7,8,9]. Also, such devices have some important drawbacks, such as structure failure, calcifications, infections, thrombosis, etc.…”

Section: Introductionmentioning

confidence: 99%

Advanced Drug-Eluting Poly (Vinyl Chloride) Surfaces Deposited by Spin Coating

Duta

Maximov²,

Trușcă

et al. 2019

Medicina

View full text Add to dashboard Cite

Background and objectives: Medical devices such as catheters are used on a large scale to treat heart and cardiovascular diseases. Unfortunately, they present some important drawbacks (structure failure, calcifications, infections, thrombosis, etc.), with the main side effects occurring due to adhesion and proliferation of bacteria and living cells on the surface of the implanted devices. The aim of this work is to modify the surface of polyvinyl chloride (PVC), an affordable biocompatible material, in order to reduce these aforementioned side effects. Materials and Methods: The surface of PVC was modified by depositing a thin layer also of PVC that incorporates an active substance, dicoumarol (a well-known anticoagulant), by spin coating process. The modified surfaces were analyzed by Fourier-transform infrared (FT-IR) microscopy, Fourier-transform infrared (FT-IR) spectroscopy, Ultraviolet-visible spectroscopy (UV-VIS), and Scanning electron microscopy (SEM) in order to determine the surface morphology and behavior. The samples were tested for Gram-positive (S. aureus ATCC 25923) and Gram-negative (P. aeruginosa ATCC 27853) standard strains from American Type Culture Collection (ATCC). Results: The material obtained had a smooth surface with a uniform distribution of dicoumarol, which is released depending on the deposition parameters. The concentration of dicoumarol at the surface of the material and also the release rate is important for the applications for which the surface modification was designed. PVC modified using the proposed method showed a good ability to prevent salt deposition and decreased the protein adhesion, and the resistance to bacterial adherence was improved compared with standard PVC.

show abstract

“…They can be developed either by a chemical method, including functionalization, polymerization, or derivatization, or a physical approach with consideration of the modification of the surface architecture . In addition to polymers possessing an intrinsic antibacterial activity ( R ), the antibacterial properties can be achieved through (1) the coating or adsorption of an antibacterial agent onto the polymer surface, (2) the immobilization of an antibacterial agent in the polymer via ionic or covalent bonding, or (3) the direct incorporation of an antibacterial agent into the polymer during its synthesis or processing . A number of conventional and nonconventional antibacterial agents have been discussed .…”

Section: Introductionmentioning

confidence: 99%

“…Recently, antibacterial agents with particle structures in their nanometric or submicrometer forms have been investigated. They usually consist of silver, copper, zinc oxide (ZnO), coated silica particles, and lately, carbon nanotubes Silver (Ag) has long been known as antibacterial agent; it possesses a wide range of activities against bacteria, molds, and yeasts . Also, ZnOs have proven to strongly inhibit the action of pathogenic microbes .…”

Section: Introductionmentioning

confidence: 99%

Electrospun polyurethane membrane with Ag/ZnO microparticles as an antibacterial surface on polyurethane sheets

Pelíšková

Slobodian

Sedlařík

et al. 2015

J of Applied Polymer Sci

View full text Add to dashboard Cite

A method of antibacterial modification of the polyurethane (PU) surface is presented in this article. An electrospun PU membrane with an incorporated antibacterial agent was applied as a coating of the PU sheets. As an antibacterial agent, a hybrid bimetallic filler was used; it combined the antibacterial effects of silver and zinc oxide. With an electrospun submicrometer‐fiber membrane, the filler was uniformly and thinly applied on the PU surface by compression molding. The antibacterial activities of three filler concentrations were tested, and they demonstrated an effective antibacterial action against Staphylococcus aureus and Escherichia coli. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43020.

show abstract

Antimicrobial Silver Nitrate-doped Polyvinyl Chloride Cast Films: Influence of Solvent on Morphology and Mechanical Properties

Cited by 10 publications

References 39 publications

Cinchonidinyl-Based Acrylic and Methacrylic Homopolymers: Synthesis, Characterization, and Antibacterial Activity

Cinchonidinyl-Based Acrylic and Methacrylic Homopolymers: Synthesis, Characterization, and Antibacterial Activity

Advanced Drug-Eluting Poly (Vinyl Chloride) Surfaces Deposited by Spin Coating

Electrospun polyurethane membrane with Ag/ZnO microparticles as an antibacterial surface on polyurethane sheets

Contact Info

Product

Resources

About