Antimicrobial screening of selected flora of Pakistan

Zia-Ul-Haq, Muhammad; Ahmad, Mansoor; Mehjabeen, M; Jehan, Noor; Ahmad, Shakeel; Qayum, Mughal; Marwat, Khan

doi:10.2298/abs1103691z

Cited by 29 publications

(16 citation statements)

References 4 publications

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“…Pakistan is a rich source of medicinal plants majority of which are unexplored for their potential. Currently many studies have been carried out to authenticate tagged medicinal activities of these plants (Nisar et al, 2010a;b;c;Qayum et al, 2012;Rizwan et al, 2012;Zia-Ul-Haq et al, 2011). Hence, the current study has been designed for evaluating the antibacterial activity of H. nepalensis.…”

Section: Resultsmentioning

confidence: 99%

Biological screening of ethyl acetate extract of Hedera nepalensis stem

Uddin¹,

Khan²,

Alamzeb³

et al. 2012

Afr. J. Pharm. Pharmacol.

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Hedera nepalensis is commonly used in folk medicines for the treatment of cough and other human ailments; therefore it was selected for phytochemical and antimicrobial screening. Its phytochemical screening showed the presence of different classes of secondary metabolites. The ethyl acetate extract of its stem showed the presence of steroids, terpenoids, saponins and flavonoids. Terpenoids and flavonoids were present in chloroform and ethyl acetate fractions, steroids were present in chloroform and ethyl acetate crude extract. Ethyl acetate and chloroform fractions were found most active. Among the organisms tested, Escherichia coli was the most sensitive to the plant extract as it displayed the greatest inhibitory zone (20:0 mm).

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Section: Resultsmentioning

confidence: 99%

Biological screening of ethyl acetate extract of Hedera nepalensis stem

Uddin¹,

Khan²,

Alamzeb³

et al. 2012

Afr. J. Pharm. Pharmacol.

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“…These plants are rich in extensive variety of secondary metabolites such as tannins, terpenoids, alkaloids, flavonoids, etc, having antimicrobial properties (Dahanukar et al, 2000;Aidah et al, 2014). Zia-ul-Haq et al (2011, 2012 tested methanolic and ethanolic extracts of seeds of medicinal plants against various species of bacteria, fungi and nematode. Most of the botanical compounds of higher plants degrade more rapidly within few days or few hours as compared to synthetic pesticides, safe and ecofriendly and have been successful in management of plant diseases (Riaz et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Analysis and Antifungal Efficacy of Rhizome Extracts of various plants against Fusarium Wilt and Root Rot of Tomato

Chohan¹,

Perveen²

2015

IJAB

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To cite this paper: Chohan, S. and R. Perveen, 2015. Phytochemical analysis and antifungal efficacy of rhizome extracts of various plants against fusarium wilt and root rot of tomato. lycopersici, whereas, least inhibition was observed against F. solani. Correspondingly, conidial germination of test fungi was almost completely reduced by A. sativum extract. Phytochemical screening of crude extract revealed the presence of flavonoids, terpenes, saponins, whereas, A. sativum was also found rich in steroids, tannins, glycosides and coumarins. Tannins were not detected in C. longa. Total phenol contents (TPC) were present in highest quantity ((54.24GAEmg/g) in A. sativum followed by Z. officinale (29.80GAEmg/g), whereas, rhizomes of C. longa contained lowest TPC (25.45GAEmg/g). It was concluded that rhizome extracts of A. sativum possesses sufficient antifungal activity under controlled conditions to warrant a further investigation under field conditions.

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“…Of them S. aureus and S. maltophilia were resistant to the widely used antibiotics ( Table 1). The isolates which exhibited antimicrobial activity against the test organisms have shown the resemblance to that reported in previous studies [34][35][36][37]. Six bacteria, including three Gram positive organisms were selected for this study.…”

Section: Resultsmentioning

confidence: 72%

Studies on Isolation and Characterization of Antibiotic Producing Microorganisms from Industrial Waste Soil Sample

Singh¹

2012

TONUTRAJ

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Antibiotics are one of the most important commercially exploited secondary metabolites produced by the bacteria and employed in a wide range. Most of the antibiotic producers used today are the soil microbes. Fungal strains and streptomyces members are extensively used in industrial antibiotic production. Bacteria are easy to isolate, culture, maintain and to improve their strains. Microbes are omni present and exist in a competitive environment. Bacillus species being the predominant soil bacteria because of their resistant endospore formation and production of vital antibiotics like bacitracin etc. are always found inhibiting the growth of the other organisms. In the present paper a soil bacterium with the antibiotic activity was screened and studied for morphological characters probably providing valuable information about the strain. The inhibitory activity of the organism was checked against some of the important opportunistic microbial flora and inoculated into an appropriate designed media depending on the bacterial requirements, and incubated for 48 hrs at 37 0 C. The produced compound was extracted by solvent extraction and assayed for its activity. Enhancement in the antibiotic production was studied under various parameters like temperature, pH, carbon source concentration, and sodium nitrate concentration, probably helping in the industrial production. The extracted substance was found effective against the gram positive endospore forming bacilli and gram positive cocci. Though a large list of antibiotics are known to be commercially available, the search for the most potential one is still on, and this work may provide some potential information on the antibiotic production and the control of microbial strains.

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Antimicrobial screening of selected flora of Pakistan

Cited by 29 publications

References 4 publications

Biological screening of ethyl acetate extract of Hedera nepalensis stem

Biological screening of ethyl acetate extract of Hedera nepalensis stem

Phytochemical Analysis and Antifungal Efficacy of Rhizome Extracts of various plants against Fusarium Wilt and Root Rot of Tomato

Studies on Isolation and Characterization of Antibiotic Producing Microorganisms from Industrial Waste Soil Sample

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