Antimicrobial Resistance: The 'Other' Pandemic!

Singhal, Tanu

doi:10.1007/s12098-021-04008-9

Cited by 10 publications

(6 citation statements)

References 41 publications

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“…The complexity required to deal with the problem of AMR is apparent and the need for collaborative participation of stakeholders as a principal solution for AMR is recommended ( 10 ). Also, aside from the overuse of antibiotics as a primary driver, there are other factors that contribute to increased prevalence ( 14 ).…”

Section: Discussionmentioning

confidence: 99%

Mapping the effect of antimicrobial resistance in poultry production in Senegal: an integrated system dynamics and network analysis approach

Aboah,

Ngom,

Emes

et al. 2023

Front. Vet. Sci.

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The impact of antimicrobial resistance (AMR) extends beyond the farm-level to other stakeholders warranting the need for a collaborative approach to combat AMR while optimising production objectives and safeguarding human health. This study maps out the effect of AMR originating from poultry production in Senegal and highlights the entry points for interventions from stakeholders’ perspectives. A causal loop diagram (CLD) was developed following a group model building procedure with 20 stakeholders and integrated with network analysis by translating the CLD into an unweighted directed network. Results indicate that with an eigenvector centrality of 1, 0.85, and 0.74, the production cost, on-farm profit, and on-farm productivity, respectively are the most ranked influential variables driving the complexity of AMR in the poultry production system. Two reinforcing feedback loops highlight the dual benefits of improving on-farm productivity and increasing on-farm profit. However, one balancing feedback loop that revolves around the causal link between producers’ investment in qualified human resource personnel to ensure good farm management practices underline the financial implication of producers’ investment decisions. The findings provide precursory groundings for the development of a quantitative SD model, the formulation of intervention scenarios and ex-ante impact assessment of the cost-effectiveness of the interventions.

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Section: Discussionmentioning

confidence: 99%

Mapping the effect of antimicrobial resistance in poultry production in Senegal: an integrated system dynamics and network analysis approach

Aboah,

Ngom,

Emes

et al. 2023

Front. Vet. Sci.

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“…The primary reasons for antibiotic overuse are the higher rate of infections due to poor healthcare discarding, poor water quality, low immunization, and malnutrition. Easy availability of antibiotics and poor prescriber knowledge or over-the-counter (OTC) purchase of antibiotics also trigger the overuse of antibiotics (Singhal 2022).…”

Section: Antibiotics Mechanism Of Action and Resistancementioning

confidence: 99%

“…Microbes develop the potential to defeat the antibiotics used to kill them. Intensive use of antibiotics in veterinary and human healthcare sectors without proper knowledge of the dosage used and unnecessary antimicrobials in agricultural practices promote antibiotic resistance globally (Singhal 2022). Antibiotic-resistant bacteria have been a severe threat in the last three decades as many pathogenic and non-pathogenic microbes have become antibioticresistant (Ventola 2015).…”

Section: Introductionmentioning

confidence: 99%

Fish Epidermal Mucus as a Source of Diverse Therapeutical Compounds

Hussain

Sachan

2023

Int J Pept Res Ther

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Microbes are helpful and destructive to human health and other living organisms. Microbes can be eliminated by using antibiotics against them, but their capability to resist regularly encountering antibiotics makes them more injurious. Microbes can adjust and adapt according to the chemicals used against them and become antibiotic resistant. Thus, the requirement for novel antimicrobial compounds increases with time to treat antibiotic-resistant microbes. Fish epidermal mucus encounters various pathogens present in their surrounding environment. It has become a rich source of novel antimicrobial compounds mainly antimicrobial peptides that can be used against various antibiotic-resistant pathogenic microbes. Compounds extracted from epidermal mucus can be used synergistically with other antibiotics or resistance modifying agents to inhibit the growth of resistant microbes. Fishes are consumed as a protein-rich food source worldwide and contribute to the world economy. Diseases in fish cause significant losses in the economic benefits exploited by fishermen and industries based on fisheries products. This paper will review compounds from fish epidermal mucus and their use to control the growth of antibiotic-resistant or non-resistant pathogenic microbes of humans and fishes. So, to increase fisheries’ economic benefits and decrease infections involving resistant microbes.

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“…The remaining one-third genome at the 3′-end encodes various ORFs. [56] From these ORFs, four ORFs encode for glycoprotein (S), membrane (M), envelope (E), and nucleocapsid proteins (N), while S, E, and M are present on the surface of the membrane. Accessory proteins are encoded with other ORFs.…”

Section: Different Aspects Of the Omicron Variant From New Variants O...mentioning

confidence: 99%

Environmental pollutants and their impact on COVID‐19 spread: Current problem and future resolutions

Patil

Parthasarathy

Matkar³

et al. 2023

Carbon Neutralization

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COVID‐19 is the greatest crucial universal health issue of the century and the extreme challenge that came after the 2nd World War faced by humankind. In 2019, different strains of the coronavirus have emerged drastically, that as severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) which is the causative agent of corona disease. As far as human civilization history, there have been occurrences of severe diseases and outbreaks of various viruses. According to World Health Organization reports, throughout the world, the present outbreak of COVID‐19 has engulfed more than 200 countries affecting 241,471,559 individuals and more than 4,914,092 people lost their lives. SARS‐CoV‐2 outbreak is severely disturbing the worldwide economy at present. The urgent need of recent times is to understand the environmental aspect of COVID‐19 disease. Hence to fulfill this point, the present review article is compiled with a brief discussion about all the minute points of the COVID‐19 pandemic related to the environment: origin and present scenario, the occurrence of SARS‐CoV‐2 in environmental habitats, the effect of COVID‐19 on human health, and environment, environmental factors influencing the transmission and spreading of SARS‐CoV‐2. This review explains micro and macro pollutants in hospital and urban wastewater influencing COVID‐19, detection of SARS‐CoV‐2, current global drug strategies to control replication and spread of SARS‐CoV‐2 from the environment, future approaches, and guidelines to prevent and control upcoming pandemics. The SARS‐CoV‐2 structural details and their effect on humans have been already well presented but the research about environmental factors affecting COVID‐19 could be important points to fight present and future pandemics.

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Antimicrobial Resistance: The 'Other' Pandemic!

Cited by 10 publications

References 41 publications

Mapping the effect of antimicrobial resistance in poultry production in Senegal: an integrated system dynamics and network analysis approach

Mapping the effect of antimicrobial resistance in poultry production in Senegal: an integrated system dynamics and network analysis approach

Fish Epidermal Mucus as a Source of Diverse Therapeutical Compounds

Environmental pollutants and their impact on COVID‐19 spread: Current problem and future resolutions

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