Antimicrobial resistance patterns of bacteria isolated from dogs with otitis

Abstract

Antimicrobial-resistant bacteria in dogs can be transmitted to humans and close contact between dogs and people might foster dissemination of resistance determinants. The aim of our study was to describe the antimicrobial resistance (AMR) pattern of the major causative agents of canine otitis – one of the most common diseases in dogs – isolated in France. Data collected between 2012 and 2016 by the French national surveillance network for AMR, referred to as RESAPATH, were analysed. Resistance trends were investigated using non-linear analysis (generalised additive models). A total of 7021 antibiograms were analysed. The four major causative agents of canine otitis in France were coagulase-positive staphylococci, Pseudomonas aeruginosa, Proteus mirabilis and streptococci. Since 2013, resistance to fluoroquinolones has been on the decrease in both P. aeruginosa and Staphylococcus pseudintermedius isolates. For P. aeruginosa, 19.4% of isolates were resistant to both enrofloxacin and gentamicin. The levels of multidrug resistance (acquired resistance to at least one antibiotic in three or more antibiotic classes) ranged between 11.9% for P. mirabilis and 16.0% for S. pseudintermedius. These results are essential to guide prudent use of antibiotics in veterinary medicine. They will also help in designing efficient control strategies and in measuring their effectiveness.

Effectiveness of Tobramycin and Ciprofloxacin Against Bacterial Isolates in Canine Otitis Externa in Uberaba, Minas Gerais

“…In terms of the quinolones, although P. aeruginosa has been found to be resistant to enrofloxacin, as described in other works (13,26,27) , the same phenomenon was not observed for ciprofloxacin in this study. Excessive use of quinolones in the antibiotic therapy procedures with dogs may explain the resistance to enrofloxacin and perhaps in the future, ciprofloxacin (26,27) .…”

Prevalence of Antimicrobial Resistance in Bacterial Isolates from Dogs and Cats in a Veterinary Diagnostic Laboratory in Colombia from 2016–2019

“…pseudointermedius of 33% compared to a prevalence of 4.3% for all other Staph spp. combined [14]. In our study, multi-drug resistance was observed at about the same level (17-19%) for the CoPS isolates compared to 11% in the CoNS.…”

Antimicrobial Resistance in Bacteria Isolated From Cats and Dogs From the Iberian Peninsula

“…The most common ear pathogens isolated from dogs are coagulase-positive staphylococci ( Staphylococcus pseudintermedius ) and P. aeruginosa ( Cole et al, 1998 ). By contrast, a recent study conducted in France showed that the major causative agents of dog otitis were coagulase-positive staphylococci, P. aeruginosa , P. mirabilis , and streptococci ( Bourély et al, 2019 ). In that study, the authors found that since 2003 resistance to fluoroquinolones has been decreased in both P. aeruginosa and S. pseudintermedius isolates, resulting for P. aeruginosa , 19.4% of isolates were resistant to both enrofloxacin and gentamicin ( Bourély et al, 2019 ).…”