IntroductionSince the late 1970s, increasing resistance to antibiotics in strains of Vibrio cholerae (Vc) has been observed and now threatens the optimal management of moderate to severe cases of cholera. Epidemics caused by antibiotic-resistant Vibrio cholerae are fraught with higher mortality. It is therefore important to monitor the evolution of antibiotic sensitivity of microbial strains in general and of Vibrio cholerae O1 in particular in each African country in order to better adapt treatment.
Objective Describe the long-term evolution of the antibiotic resistance profile of Vibrio cholerae O1 strains isolated in eastern Democratic Republic of Congo between January 2011 and June 2022.
Material and MethodsThis is a cross-sectional, retrospective and prospective study with descriptive and analytical purposes during the period from January 1, 2011 to June 30, 2022. All isolates positive for Vibrio cholerae O1 in patients from the eastern provinces of the Democratic Republic of Congo were included. Samples with missing data were excluded.
ResultsIn total, 4832 isolates of V c O1 were collected, more than half of them (72.46%, n=3175) in the province of North Kivu. Of the 3