Antimicrobial resistance in urinary bacterial isolates from pregnant women in rural Tanzania: Implications for public health

Abstract

Common variable immunodeficiency with an associated broad immunoglobulin (0.7%) deficit affecting all subclasses, was revealed in a 27-y-old previously healthy female, upon development of a severe pneumococcal meningitis. We report the third case of purulent meningitis complicating this primary immunodeficiency, and the second due to Streptococcus pneumoniae. Clinicians should maintain an elevated suspicion for congenital immunodeficiency, especially when observing adult patients with a negligible prior history.

Asymptomatic bacteriuria and symptomatic urinary tract infections in pregnancy

“…Ampicillin as a single agent has fallen out of favour due to high resistance rates [75][76][77]. The advantage of using an aminoglycoside is that high renal parenchymal concentrations are obtained but there is a theoretical risk of ototoxicity and nephrotoxicity in the fetus because the drug crosses the placenta.…”

Pielonefritis Aguda en El Embarazo Y Susceptibilidad Antimicrobiana De Uropatógenos: Comparación De Dos Décadas

“…Blomberg y cols (22), reportaron una frecuencia de sólo 25,2%, mas en su estudio, hay cepas gramnegativas no identificadas, las cuales sumaban un 21% del total de casos. Este patógeno continúa siendo el principal agente causante de ITU tanto a nivel mundial como en nuestra institución, probablemente debido a su gran capacidad de invadir células epiteliales mediante adhesinas y hemolisinas.…”

“…En el análisis de la sensibilidad general de los uropatógenos aislados en nuestra serie, encontramos que no hubo variación significativa en cuanto al patrón de resistencia con respecto al año 2001, siendo similar también a los mostrados en los estudios internacionales (6,(19)(20)(21)(22). Cabe destacar la buena sensibilidad de la E. coli a las cefalosporinas de primera generación, así como la susceptibilidad del 100% de los casos de SGB a la ampicilina.…”

Bacteriuria in Pregnant and Non Pregnant Women in Benghazi Acomparative Study

“…Gram-positive organisms like Staphylococcus saprophyticus also cause bacteriuria (10). There are several ways to diagnose UTI, but urine culture still remains the most reliable tool for its diagnosis (2). In Benghazi, Libya, the data are not yet available on the prevalence of bacteriuria (symptomatic, asymptomatic) during pregnancy.…”

“…UTI is evident when there are 105 or more of microorganisms of a single strain of bacterium per millilitre in midstream urine samples (2). UTI affects all age groups, but women are more susceptible than men, due to short urethra, absence of prostatic secretion, pregnancy and easy contamination of the urinary tract with faecal flora (3).…”