“…Due to the spreading of high risk nosocomial infections, MRSA has been disseminated recently in the community [ 14 ], but it is less frequently found in the sewage system. When compared to gram-negative bacteria, gram-positive bacteria rapidly develop resistance to key antibiotics (e.g., methicillin and then penicillin) [ 12 ]. However, some Gram-positive resistant bacteria, like Vancomycin resistant Enterococci (VRE) (which exist in the gastrointestinal tract), are frequently found in the wastewater and have been identified as a potential infectious risk for hospitals [ 13 ].…”