Antimicrobial properties and phenolic contents of medicinal plants used by the Venda people for conditions related to venereal diseases

Mulaudzi, R.B.; Ndhlala, A.R.; Kulkarni, Manoj G.; Finnie, J.F.; Staden, J. Van

doi:10.1016/j.jep.2011.03.022

Cited by 113 publications

(69 citation statements)

References 39 publications

(42 reference statements)

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“…The water extract of C. spinosa could be considered to have no inhibitory activity against P. aeruginosa since its MIC was 10 mg/ml. Mulaudzi et al (2011) considered extracts with MIC > 8 mg/ml as having no inhibitory potential. Farmers are therefore faced with two constraints when they use water as an ingredient; (1) poor extraction capacity and (2) weak to very poor inhibitory effects of the resultant extracts.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Efficacy of Extracts From Plants Used by Small-Holder Farmers in the Treatment of Dermatophilosis in Cattle

Ndhlovu

Masika

2017

Afr J Tradit Complement Altern Med

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Background: Bovine dermatophilosis, an important skin disease of cattle caused by Dermatophilus congolensis, negatively impacts the livelihoods of small-holder farmers in Zimbabwe. This impact is through, morbidity, loss of draught animal power, costs incurred to manage the disease, losses associated with devalued damaged hides and the resultant culling of some of the affected cattle. Due to the inaccessibility of conventional drugs to manage bovine dermatophilosis, farmers have been reported to use local medicinal plants to manage the disease. The aim of the study was to evaluate the in vitro antimicrobial activities of three plants that small-holder farmers in Zimbabwe used to manage bovine dermatophilosis. Methods: Dried plant materials were ground into powder and extracted individually using, water, 80 % acetone and 80 % methanol. The antimicrobial properties of the plants were evaluated against two Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and one Gram-positive (Staphylococcus aureus) reference bacterial strains. They were further evaluated against a field isolate of Dermatophilus congolensis. The assays used were the disc diffusion, minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). Results: Acetone and methanol extracts had superior inhibitory activities than did those of water. Pterocarpus angolensis DC extracts had better inhibitory properties with absolute MIC values of 0.156 -5 mg/ml, Cissus Quadrangularis L had MIC values in the range 0.156 -5 mg/ml while that of Catunaregam spinosa Thunb, Terveng was 0.156 -10 mg/ml. Dermatophilus congolensis was more sensitive to Pterocarpus angolensis DC average MIC = 0.63 mg/ml than to Cissus quadrangularis L average MIC = 1.25 mg/ml and Catunaregam. spinosa Thunb, Terveng average MIC = 2.08 mg/ml. Conclusion: These results suggest the potential antibacterial activities of extracts of the three plants and hence farmers are, in a way, justified in using the plants. Better results (lower MIC) could be obtained by extracting and evaluating pure active compounds of the plants.

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Section: Discussionmentioning

confidence: 99%

In Vitro Efficacy of Extracts From Plants Used by Small-Holder Farmers in the Treatment of Dermatophilosis in Cattle

Ndhlovu

Masika

2017

Afr J Tradit Complement Altern Med

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“…There is a wide interest in the use of medicinal plants by Venda people and this has led to several publications (Mahwasane et al, 2013;Mulaudzi et al, 2011 andSamie et al, 2010;Tshikalange et al, 2005;Mabogo 1990;Arnold and Gulumiam, 1984). In this region, traditional medicine still plays a significant role in the lives of local people, despite recent advances in Western medicine .…”

Section: Introductionmentioning

confidence: 99%

The traditional use of plants to manage candidiasis and related infections in Venda, South Africa

Masevhe

McGaw

Eloff

2015

Journal of Ethnopharmacology

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Ethnopharmacological relevance: This paper presents results of an ethnobotanical survey of medicinal plants used for the management of candidiasis and related fungal infections in the Venda area, South Africa. Materials and Methods:Ethnobotanical data about the uses of plants were gathered from eleven rural traditional healers using semi-structured interviews.Results: A total of 45 species belonging to 24 different families were identified, of which the dominant family was the Fabaceae with 13 species (28.9%) followed by the Asteraceae and Solanaceae with 3 species each (6.7 %). A total of 28 of these plant species (62.2%) have been shown to have anticandidal activity and 14 species (31%) have been recorded for antifungal uses in the literature. Amongst the 45 species recorded, 51% were trees, 33% were shrubs, and 16% were herbs. The most widely used plant species were Acacia caffra, Clerodendrum glabrum, Croton gratissimus, Elaeodendron transvaalense, Faurea saligna, Hippocratea longipetiolata, Osyris lanceolata, Richardia brasiliensis, Schkuhria pinnata, Schotia brachypetala, Spilanthes acmella, Strychnos potatorum, Vangueria infaustasubsp. infausta and Withania somnifera. The plant parts mostly used in the therapeutic preparations were roots (27.7%), bark (23.2%), and a combination of roots, bark (18.7%) and leaves (14.3%). Decoctions (44.4%), infusions (20%), macerations (17.7%), burning (11.4%) and paste (6.5%) were used. Most of the herbal remedies were administered orally. The main factors threatening the conservation status of these plants are unsustainable methods of harvesting, logging for firewood, building materials and crafts. Conclusion:The Venda area is rich in plant diversity and local indigenous knowledge of medicinal plants can play an important role as a model for low cost primary health care. Further studies are in progress to validate the indigenous plants recorded as traditional remedies in this area.

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“…to treat diarrhea, heavy menstruation, nose bleeding, headache, stomach-ache, parasitic worms, sores and skin problems (Takawira-Nyenya, 2005). Pharmacological studies on P. angolensis revealed antibacterial activity of seeds (Steenkamp et al, 2004), stem bark, roots and leaf extracts (Luseba et al, 2007;Mulaudzi et al, 2011;Samie et al, 2009) and antifungal activity of leaf and bark extracts (Mulaudzi et al, 2011). The latter also showed HIV-1 reverse transcriptase inhibitory activity (Mulaudzi et al, 2011) as well as anthelmintic effects (McGaw et al, 2007;Molgaard et al, 2001).…”

Section: Pterocarpus Angolensismentioning

confidence: 98%

Woody species from the Mozambican Miombo woodlands: A review on their ethnomedicinal uses and pharmacological potential

Moura¹,

Duvane²,

Silva³

et al. 2018

J. Med. Plants Res.

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Miombo woodlands cover about two thirds of Mozambique national territory. They provide a wide collection of goods and services to the formal and informal economies. A review on the traditional uses of 15 Miombo tree species in human and animal health, as well as the status of research towards the identification of bioactive compounds is presented. Among the 15 species selected, 12 have been screened for their biological activity and/or pharmacological properties and/or toxicity. The information gathered in this work is a key to further exploit potential new uses and future opportunities for research and valorization of the selected species.

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Antimicrobial properties and phenolic contents of medicinal plants used by the Venda people for conditions related to venereal diseases

Cited by 113 publications

References 39 publications

In Vitro Efficacy of Extracts From Plants Used by Small-Holder Farmers in the Treatment of Dermatophilosis in Cattle

In Vitro Efficacy of Extracts From Plants Used by Small-Holder Farmers in the Treatment of Dermatophilosis in Cattle

The traditional use of plants to manage candidiasis and related infections in Venda, South Africa

Woody species from the Mozambican Miombo woodlands: A review on their ethnomedicinal uses and pharmacological potential

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