Antimicrobial prescribing pattern in urinary tract infection in a tertiary care hospital

Naik, Samira Kumar; Samal, Satyajit; Sahu, Susanta Kumar; Rath, Bhabagrahi

doi:10.5455/njppp.2017.7.0623506072017

Cited by 3 publications

(3 citation statements)

References 4 publications

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“…Total of 121 antibiotics were prescribed in 84 UTI patients among which Cefoperazone + sulbactam (23.97%) was mostly prescribed followed by amikacin (14.88%) and piperacillin + tazobactam (14.05%). Similar results were observed in the study conducted by Samira Kumar Naik et al, where it was observed that cephalosporins are the mostly prescribed antibiotics in the management of UTI [23].…”

Section: Comparision Of Total Cost Of Antibioticssupporting

confidence: 89%

Prescribing Pattern of Antibiotics in Bacterial Infectious Diseases in a Corporate Care Hospital

Ramanath

Harshitha

Chamundi

et al. 2022

AJRID

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Background: The antibacterial preparations are commonly used to control various bacterial infections, which may vary from one hospital to other. Hence, understanding the antibiotic practice will help the pharmacist gain knowledge and implement the safe use of drugs. Objectives: To assess the antibacterial use in the management of the selected bacterial infections Methodology: This study is a retrospective, observational, cross-sectional study over six months as per the inclusion & exclusion criteria in the Inpatients. A well-designed questionnaire was used for collecting the required data, and the obtained data were subjected to descriptive statistics. Results and Discussion: Out of 334 cases observed, 54.19% were female, and 45.81% were male. The mean stays 3.81±2.21 days. Acute gastroenteritis was 59.58%, followed by UTI 25.15%. Pneumonia was 8.68%, and 6.29% had COPD. 0.30% had Acute gastroenteritis with UTI. 39.87% of patients were overweight18.35% were obese, and only 3.16% were underweight. Most of them were in the age group of 61-70, and the least was from 10-20. The mean age of the patients observed in this study was 55.21 ± 18.46. Single antibiotic therapy in 142 cases,165 cases had two antibiotics, in 24 instances three antibiotics were used, in 4patients 4 antibiotics were used for management of the infections. The commonly used antibiotics in managing bacterial infections are penicillin, cephalosporin, carbapenems, macrolides, Nitorimidazoles, quinolines, etc. The clinical outcome showed all the patients were improved, except 3 cases were discharged on request. 139 drug-drug interactions were present in this study and metronidazole (63.01%) was found to have highest major drug-drug interactions. The average cost of antibiotics used in treating Pneumonia (6534 Rs), AE of COPD (4459.7 Rs)., UTI 3778 Rs, acute GE 1176.2 Rs. Conclusions: This study showed that pharmaceutical care services are essential in the bacterial infection management for the prevention of drug-drug interactions and minimization of the cost (rational drug usage promotion)

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Section: Comparision Of Total Cost Of Antibioticssupporting

confidence: 89%

Prescribing Pattern of Antibiotics in Bacterial Infectious Diseases in a Corporate Care Hospital

Ramanath

Harshitha

Chamundi

et al. 2022

AJRID

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“…Samira et al, study was similar to our study in which the ceftriaxone was the highest prescribed among the cephalosporins. 14 Among 50 patients, subjects with age group 18-33 are mostly affected with uUTIs 23 (46%). illiterate (52%) was predominantly affected with uUTI when compared to literate (48%).…”

Section: Discussionmentioning

confidence: 99%

Prescribing pattern of antibiotic regimen in inpatients with uncomplicated urinary tract infection

Kumari¹,

Kumar²,

Sireesha³

et al. 2023

World J. Adv. Res. Rev.

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Introduction: Uncomplicated urinary tract infection is among the more common infections in females. The S3 guideline contains recommendations based on current evidence for the rational use of anti - microbial agents and for the prevention of inappropriate use of certain classes of antibiotics and thus of the resulting drug resistance. Methodology: A hospital based, prospective, observational type of study to be conducted in Inpatient department, Government general hospital, Kadapa, Andhra Pradesh. Study was conducted over a period of 6 months (September 2019 to Feb 2020). Results: According to our study, patients with illiterate (26) were mostly affected when compared to literate (24), housewives were mostly affected with uUTI (44) with age group of 18-33 were mostly affected (23), 49-63 age group people were less affected with uUTI(8) . Cystitis was the mostly commonly seen in patients (43) when compare to pyelonephritis. Ceftriaxone was mostly commonly prescribed drug when compare to other antibiotics (27). Conclusion: We found that majority of patients were treated with third- generation cephalosporine class of drug (ceftriaxone) followed by ciprofloxacin, nitrofurantoin.

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“…Moreover, the nature and pattern of antimicrobial prescribing practice changes with time as spectrum of pathogens change and new antimicrobials are introduced. [3][4][5][6][7][8][9][10][11][12][13][14] Culture sensitivity tests were also important in case of UTI to go for a specific antibiotic treatment rather than the empirical treatment for the patients. 15,16 Ideally, the antimicrobial agent chosen should be well tolerated, well absorbed, achieve high urinary concentrations, and have a spectrum of activity limited to the known or suspected pathogen(s).…”

Section: Introductionmentioning

confidence: 99%

A prospective study on antibiotic resistance pattern in patients with urinary tract infection

Singh,

Thomas,

Ramaiah

2023

Int J Basic Clin Pharmacol

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Background: Antibiotics are a blessing to the mankind in the realm of medical treatment. Quite contrary to that fact, they may cause risks in medical treatments of patients if these antibiotics are not taken under medical guidelines. In the current scenario it is a huge challenge for selecting appropriate antibacterial agents for the treatment of UTI. This study aims to evaluate the prescription & resistance pattern of antibiotics in patients with urinary tract infection. Methods: A prospective observational study was carried out for a period of 1 year. Data on 100 research participants' reports and the results of their tests for antibiotic resistance were taken from the microbiology department's records, evaluated, and represented as percentages. Observations were made and meticulously recorded. Results: Out of 100 study participants, Escherichia coli was the most common pathogen with a total of (35%) followed by Klebsiella (17%), Enterococcus with (16%). E. coli were highly resistant to Ampicillin (88.6%) and Cefazolin (88.6%), Ceftraixone (85.3%). Klebsiella were highly resistant to Ampicillin (100%) Cefazolin (93.3%), Cefuroxime (85.7%). Enterococcus were highly resistant to Tetracycline (92.9%) Ciprofloxacin (85.7%), Levofloxacin (81.8%). Where, E. coli were highly sensitive to Amikacin, Imipenem, Ertapenam. Klebsiella were highly sensitive to Meropenem, Cefoperazone/Sulbactam, Amikacin. Enterococcus was highly sensitive to Linezolid, Teicoplanin, Vancomycin. Conclusions: Most of the identified bacteria were resistant to several of the popular antibiotics used in clinical settings. Consequently, it is vital to prescribe antibiotics rationally both before and after culture reports.

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Antimicrobial prescribing pattern in urinary tract infection in a tertiary care hospital

Cited by 3 publications

References 4 publications

Prescribing Pattern of Antibiotics in Bacterial Infectious Diseases in a Corporate Care Hospital

Prescribing Pattern of Antibiotics in Bacterial Infectious Diseases in a Corporate Care Hospital

Prescribing pattern of antibiotic regimen in inpatients with uncomplicated urinary tract infection

A prospective study on antibiotic resistance pattern in patients with urinary tract infection

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