Antimicrobial potential of two different Hypericum species available in India

Abstract

The antimicrobial activity of extracts of the leaves and stems of two different varieties of Hypericum was evaluated by the disc diffusion method. Petroleum ether, acetone, chloroform and methanol extracts of Hypericum mysorense and Hypericum patulum stems and leaves were investigated for their antimicrobial activity against six different strains of bacteria and fungi by the zone of inhibition method (ZIM). The results showed that both the stem and leaf extracts of both species have a very broad spectrum of antibacterial activity. The petroleum ether and acetone extract of the leaves and stems of H. mysorense did not show antifungal effects against any of the six fungal organisms tested but other extracts showed a potential antifungal effect which was comparable to that of griseofulvin, the standard antifungal agent. Thus these results demonstrate that the leaf and stem extracts of both the Hypericum species have a very broad spectrum of activity and suggest that they may be useful in the treatment of various microbial infections.

Antimicrobial and Antioxidant Activities of Some Plants Used as Remedies in Turkish Traditional Medicine

“…Previous reports also showed that some Hypericum species growing in various regions of the world have a remarkably broad spectrum of antimicrobial activities (Herrera et al, 1996;Sokmen et al, 1999;Mukherjee et al, 2002;Rabanal et al, 2002;Dall'Agnol et al, 2003;Fenner et al, 2005). However, none of those studies were about the Hypericum species that were the subjects of the current study.…”

“…Therefore, research into biologically active extracts and compounds from natural sources has been of great interest to scientists in an attempt to discover new sources for drugs that may be useful in combating infectious diseases. In recent years, a large number of studies dealing with antimicrobial screening of the extracts of medicinal plants have been reported (Sokmen et al, 1999;Keles et al, 2001;Erdogrul, 2002;Mukherjee et al, 2002;Rabanal et al, 2002;Dall'Agnol et al, 2003;Fenner et al, 2005;Ozturk & Ercisli, 2005;Salehi et al, 2005). Turkish native herbs from both natural and cultivated sources are being more widely used on a commercial scale in the food industry, in traditional medicine, and for their flavoring properties (Baytop, 1999).…”

Patient Reported Outcomes and Patient Satisfaction With Hyperisince® (An Ayurvedic Medicine/Poly-Herbal Combination) in Herpes Simplex

“…Plant extracts from Hypericum mysorense, Hypericum hookerianum and Usnea complanta showed significant anti-viral efficacy in a study by Vijayan et al 6 We did a survey to evaluate patient satisfaction and patient reported (HSV infected) outcomes on efficacy and safety of herbal combination Hyperisince ® (manufactured by Biogetica ® see table 1 for ingredients; Hyperisince is licensed by Ayush as a Ayurvedic Treatment for Herpes and is marketed elsewhere as a herbal dietary supplement). Hyperisince ® is GMP certified and manufactured at Deltas Pharma Pvt.…”

Assessment of Antimicrobial Activity of Ethanol Extracts of Commiphora africana and Boswellia dalzielii

“…Unfortunately, they develop resistance to many antimicrobial agents 1 . The reason for this high resistance to commonly used antimicrobial agents may not be unconnected with the worldwide and indiscriminate use in the environment 2 . In addition, these antimicrobials sometimes cause allergic reaction and immunity suppression.…”