Antimicrobial polymeric biomaterials based on synthetic, nanotechnology, and biotechnological approaches

Rojo, Luís; García‐Fernández, Luis; Aguilar, María Rosa; Vázquez‐Lasa, Blanca

doi:10.1016/j.copbio.2022.102752

Cited by 28 publications

(6 citation statements)

References 48 publications

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“…Bioactive ceramics hydroxyapatites coatings on metallic implants [177][178][179] fluorapatite-based composites bone applications [180] bioactive glasses bone substitute and drug carrier [181] bioactive glass ceramics chemo hyperthermia [182] Biodegradable (bioresorbable)ceramics aluminium-calcium phosphate biomedical application [183] zinc-calcium phosphorous oxides postoperative tumour treatment [184] zinc-sulfate-calcium phosphates tissue engineering [185] ferric-calcium phosphorous oxides scaffolding for cell and drug delivery [186] coralline drugs [187] calcium aluminates bioactive dental materials [188] Bioinert (nonresorbable) ceramics alumina drug delivery [189] zirconia biomedical applications [190] carbons biomedical applications for tissue engineering [191] silicon nitride biomedical applications in medical implants [192]…”

Section: Bioceramics Examples Applications Referencesmentioning

confidence: 99%

Section: Bioceramics Examples Applications Referencesmentioning

confidence: 99%

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Advanced Biomedical Applications of Multifunctional Natural and Synthetic Biomaterials

Chelu,

Musuc

2023

Processes

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Biomaterials are mostly any natural and synthetic materials which are compatible from a biological point of view with the human body. Biomaterials are widely used to sustain, increase, reestablish or substitute the biological function of any injured tissue and organ from the human body. Additionally, biomaterials are uninterruptedly in contact with the human body, i.e., tissue, blood and biological fluids. For this reason, an essential feature of biomaterials is their biocompatibility. Consequently, this review summarizes the classification of different types of biomaterials based on their origin, as natural and synthetic ones. Moreover, the advanced applications in pharmaceutical and medical domains are highlighted based on the specific mechanical and physical properties of biomaterials, concerning their use. The high-priority challenges in the field of biomaterials are also discussed, especially those regarding the transfer and implementation of valuable scientific results in medical practice.

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Section: Bioceramics Examples Applications Referencesmentioning

confidence: 99%

Section: Bioceramics Examples Applications Referencesmentioning

confidence: 99%

Advanced Biomedical Applications of Multifunctional Natural and Synthetic Biomaterials

Chelu,

Musuc

2023

Processes

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“…Natural tissues are maintained by this rational design of biomaterials. Smart biomaterials play an essential role for using organic and inorganic synthesis [21]. These smart biomaterials are designed by this particular technology for providing better services and treatments to their patients.…”

Section: Trends In Cardiovascular Engineeringmentioning

confidence: 99%

Trends in Cardiovascular Engineering and Its Advances

Sikkander¹,

Kandula²

2022

TBEAH

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The aim of this study is to represent “trends in cardiovascular engineering and its advances”. Cardiovascular diseases create a negative impact on medical science. Different types of modern machines and technologies are used to reduce those diseases. Stroke, heart attacks, heart failure, heart valve complications and arrhythmia are main cardiovascular diseases. Blood vessels and heart molecules need proper supply of oxygen to maintain a healthy lifestyle. Every person should maintain a healthy diet and exercise on a daily basis to mitigate those issues significantly. Various kinds of therapies and technologies are used by a technologist to manage cardiovascular engineering in an organised manner. Every technologist must have ideas and thoughts related to usage of those technologies. For this reason, these individuals can provide better suggestions to their patients. Cardiovascular engineering helps to maintain a wide range of engineering projects and biomedical in an organised way. Up to date and modern technologies are implemented in cardiovascular engineering and its trends. Biomaterials and regenerative technologies are used to provide better services and treatments to the patients. Experienced technologists can easily provide better treatments in any emergency cases. Tissue engineering and delivery of bimolecular includes in this particular engineering process. Keyword : Cardiovascular, stroke, heart attack, biomaterials

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“…4 For example, chemical compounds such as quaternary ammonium groups and conjugated biocide molecules can be used to inhibit the attachment and growth of microorganisms on surfaces. 7,8 In recent years, researchers have explored the possibility of leveraging topography, inspired by natural surfaces with antifouling or bactericidal properties, to create antimicrobial and antifouling materials. Examples of nanostructured surfaces include rice and lotus leaves, 9,10 shark skin, 11 cicada wings, gecko skin, and dragonfly wings.…”

Section: ■ Introductionmentioning

confidence: 99%

“…These materials can be designed through various approaches such as modifying the biomaterial surface to prevent adhesion, incorporating antimicrobial substances, and combining antiadhesive and antimicrobial properties in a single coating . For example, chemical compounds such as quaternary ammonium groups and conjugated biocide molecules can be used to inhibit the attachment and growth of microorganisms on surfaces. , …”

Section: Introductionmentioning

confidence: 99%

Analysis of Antibacterial Efficacy and Cellular Alignment Regulation on Plasma Nanotextured Chitosan Surfaces

Jaramillo-Correa,

Posada,

Nashed

et al. 2023

Langmuir

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To address implant-related infections, antibacterial solutions specific to biomaterials are required to prevent bacterial proliferation. Traditional antibiotic usage has been found insufficient, motivating researchers to investigate alternative strategies such as surface modification and the application of antifouling or infection-resistant properties. A developing interest lies in designing surfaces that mimic natural antibacterial nanotopographies. In this study, we conducted a quantitative analysis of the outcomes from plasma nanotexturing, with particular emphasis on how the organization of topography influences antibacterial efficacy and the regulation of cell alignment. Plasma nanotexturing was applied to chitosan surfaces, which gradually transformed from nanopores to pillars and eventually into tilted pillars, as the plasma parameters (fluence and angle) increased. We used directed plasma nanosynthesis, a plasma-based technique that primarily induces topographical alterations on the surfaces. The surfaces were systematically characterized, incorporating methods such as scanning electron microscopy (SEM), atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS). A comprehensive comparison of the nanotextures was executed by utilizing a trapezoidal method to calculate aspect ratios and assess texture orientation by examining the gaps in the nanostructures. We evaluated antibacterial properties against E. coli and S. aureus strains and assessed the survival and alignment of human bone marrow mesenchymal stem cells. Our findings reveal a significant reduction in bacterial adhesion (>80%) and growth on nanotextured surfaces, underscoring their potential for clinical applications. Moreover, we measured cell alignment, presenting the results in both a color-coded and numerical format to demonstrate the preferential alignment orientation induced specially by the tilted nanotexture. These insights highlight the profound impacts of plasma nanotexturing, indicating its potential for innovative biomedical applications such as advanced wound healing and tissue engineering.

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Antimicrobial polymeric biomaterials based on synthetic, nanotechnology, and biotechnological approaches

Cited by 28 publications

References 48 publications

Advanced Biomedical Applications of Multifunctional Natural and Synthetic Biomaterials

Advanced Biomedical Applications of Multifunctional Natural and Synthetic Biomaterials

Trends in Cardiovascular Engineering and Its Advances

Analysis of Antibacterial Efficacy and Cellular Alignment Regulation on Plasma Nanotextured Chitosan Surfaces

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