Antimicrobial Pharmacology for Head, Neck, and Orofacial Nonbacterial Infections

Boynton, Tyler T.; Ferneini, Elie M.

doi:10.1016/b978-0-323-28945-0.00009-0

Cited by 5 publications

(6 citation statements)

References 30 publications

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“…The patients observed drowsiness 3.88%, nausea 3.27%, and skin rush 4.91%, but most of the patients, 77.51%, did not observe any side effects (Table 3). Ketoconazole and Clotrimazole drugs have found similar side effects in different studies (33)(34) Several strategies may help minimize the fungal disease in Bangladesh. To combat fungal diseases, public awareness campaigns, regulatory measures, accessible healthcare, community health workers, telemedicine, and engagement are essential.…”

Section: Discussionmentioning

confidence: 99%

Prevalence, Causes, and Management Strategies of Fungal Diseases in Northern Regions of Bangladesh

Akanda,

Sultana,

Rana

et al. 2024

sciphar

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In Bangladesh, fungus-related skin diseases are highly prevalent. Until this result began, there was no research in Bangladesh to find the cause and management strategies for fungal infection, but there is still no complete research on it. This survey aimed to evaluate the incidence, etiology, and therapeutic alternatives for various fungal ailments in Bangladesh. The research was carried out in Rajshahi from January to June 2019 by the Pharmacy Department of Varendra University. A compilation of 489 patient data was obtained throughout the investigation using a semi-structured questionnaire. The participants' ages vary from three months to seventy years; 327 are male, and 162 are female. The most prevalent skin conditions among the patients are as follows: ringworm (11.25%), skin infections affecting the ear, nose, fingers, and uterus (11.04%), acne (8.19%), allergy (9.82%), dandruff (5.11%), dermatitis (9.00%), eczema (5.73%), and scabies (7.18%). Student individuals comprise 49.28% of the patients, day workers 16.56%, housewives 16.36%, and employed 14.31%. Patients are housed in 53.17 percent concrete houses, 26.5 percent huts, and 26.18% semi-structures. Patients wash their clothing with tap water at a rate of 52%, followed by tube well water at 21.27%, pond water at 20.45%, and river water at 5.52%. It is evident from this study that fungal diseases affect individuals of all ages, including men and women. An adverse finding of the research was that over forty percent of patients do not receive accurate instructions from their physicians, which raises the risk of drug resistance and further contamination.

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Section: Discussionmentioning

confidence: 99%

Prevalence, Causes, and Management Strategies of Fungal Diseases in Northern Regions of Bangladesh

Akanda,

Sultana,

Rana

et al. 2024

sciphar

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“…Based on our findings on the comparison of individual AFAs, we are unable to make strong recommendations on the use of CLT as the best choice to prevent OC. CLT troches, the common dosage form administered in the treatment or prevention of OC (Crowley & Gallagher, 2014;Hupp, Ferneini, Boynton, & Ferneini, 2016), creates an additional burden for patients undergoing cancer therapy, especially radiotherapy, in terms of ineffective prophylactic treatment and increased cost. Patients who suffer from hyposalivation as a consequence of radiation therapy will experience difficulty in dissolving troches (Crowley & Gallagher, 2014;Hupp, Ferneini, Boynton, & Ferneini, 2016;Lalla et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

“…Hence, the effectiveness of CLT against Candida species on the mucosal layer will be affected. In addition, the administration of sugar-containing CLT troches in cancer patients will increase the colonisation of Candidaspecies on the oral mucosa due to the high concentration of salivary glucose (Akpan & Morgan, 2002;Bhattacharyya, Chandra, Singh, Raj, & Gupta, 2018;Hupp et al, 2016). Therefore, use of CLT is only recommended for those patients who are resistant to FLC, as the benefit in preventing OC overweighs the risk of adverse events.…”

Section: Discussionmentioning

confidence: 99%

Antifungal agents in preventing oral candidiasis in clinical oncology: A network meta‐analysis

et al. 2020

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Cancer treatment, especially chemotherapy and radiotherapy will lead to short and long-term adverse events which may be distressing and potentially fatal for cancer patients. Opportunistic fungal infections like oral candidiasis (OC) that affects the mucosal layer of the oral cavity due to the overgrowth of Candida species, notably Candida albicans is a relatively common adverse effect of cancer treatment (Akpan & Morgan, 2002). Recent evidence shows that there is approximately 90% of oral Candida carriage rate in patients receiving chemotherapy, which is twice the amount found in

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“…Another study showed that printing parameters had significant effects on algae cell quantity in printed samples [37]. Unlike mammalian cells, fungal cells have cell walls made of glucans, chitin, and glycoproteins [38]. The presence of the cell walls might make the fungal cells more resistant to shear stress.…”

Section: Effects Of Printing Parameters On Fungal Growth In Printed S...mentioning

confidence: 99%

Three-Dimensional Printing of Biomass–Fungi Biocomposite Materials: The Effects of Mixing and Printing Parameters on Fungal Growth

Rahman,

Bhardwaj,

Vasselli

et al. 2023

JMMP

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Biomass–fungi biocomposite materials are derived from sustainable sources and can biodegrade at the end of their service. They can be used to manufacture products that are traditionally made from petroleum-based plastics. There are potential applications for these products in the packaging, furniture, and construction industries. In the biomass–fungi biocomposite materials, the biomass particles (made from agricultural waste such as hemp hurd) act as the substrate, and a network of fungal hyphae grow through and bind the biomass particles together. Typically, molding-based methods are used to manufacture products using these biocomposite materials. Recently, the authors reported a novel extrusion-based 3D printing method using these biocomposite materials. This paper reports a follow-up investigation into the effects of mixing parameters (mixing time and mixing mode) on fungal growth in biomass–fungi mixtures prepared for 3D printing and the effects of printing parameters (printing speed and extrusion pressure) on fungal growth in printed samples. The fungal growth was quantified using the number of fungal colonies that grew from samples. The results show that, when mixing time increased from 15 to 120 s, there was a 52% increase in fungal growth. Changing from continuous to intermittent mixing mode resulted in an 11% increase in fungal growth. Compared to mixtures that were not subjected to printing, samples printed with a high printing speed and high extrusion pressure had a 14.6% reduction in fungal growth, while those with a low printing speed and low extrusion pressure resulted in a 16.5% reduction in fungal growth.

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Antimicrobial Pharmacology for Head, Neck, and Orofacial Nonbacterial Infections

Cited by 5 publications

References 30 publications

Prevalence, Causes, and Management Strategies of Fungal Diseases in Northern Regions of Bangladesh

Prevalence, Causes, and Management Strategies of Fungal Diseases in Northern Regions of Bangladesh

Antifungal agents in preventing oral candidiasis in clinical oncology: A network meta‐analysis

Three-Dimensional Printing of Biomass–Fungi Biocomposite Materials: The Effects of Mixing and Printing Parameters on Fungal Growth

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