Antimicrobial Peptides Targeting Streptococcus mutans: Current Research on Design, Screening and Efficacy

Ying, Xinxin; Xue, Guanglu; Sun, Pengxiang; Gan, Ziling; Fan, Ziqian; Liu, Bo; Han, Yaoting; Yang, Jiaqian; Zhang, Jing; Lu, Aiping

doi:10.1007/s00284-023-03540-5

Cited by 1 publication

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“…Resistance to chloramphenicol is also caused by the drug destruction by S. mutans isolates by the enzyme Chloramphenicol acetyl transferase [30]. The mechanism of resistance to Amoxicillin, which is one of the antibiotics with a synergistic effect and is characterized by its resistance to beta-lactam enzymes, does not differ from the mechanisms of resistance to other antibiotics by changing the target site of the anti-beta-lactam or by reducing the permeability of the antibiotic through the bacterial cell membrane [31].…”

Section: Resistance Of S Mutans Isolates To Antibioticsmentioning

confidence: 99%

Isolation and Identification of Oral Bacteria and Characterization for biofilm formation and antibiotics resistance

ALI

2024

wjps

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In this study, 100 bacterial isolates were obtained from tooth surface swabs of male and female patients with different ages who visited specialized centers and dental clinics in Baghdad city after they were clinically diagnosed with oral (dental) infections by specialist doctors for the period from 1/10/2022 to 1/3/2023. The methods employed to identify the bacterial isolates were the Vitek system, as well as highest isolated rate was among Streptococcus mutans species (48%). Isolates of S. mutans and their drug sensitivity was tested against 10 antibiotics using the disc diffusion process, showing that the separators’ Antibiotic resistance was larger than their sensitivity to these antibiotics. The resistance rate of the isolates to erythromycin was (98.21 and 94.64%), to amoxicillin (85.71)% for each of them, to ampicillin (80.35 and 83.92)%, to Nalidixic acid (80.35 and 87.50)%, to cefotaxime (69.64 and 75.00)%, and to chloramphenicol (69.64 and 89%), to amoxicillin–Clavulanic acid (58.92 and 76.78)%), to gentamycin (57.14 and 78.57)%, and to tetracycline the resistance rate was (55.35 and 66.07)% for each of them, respectively, while it showed high sensitivity to the antibiotics amikacin (25.00 and 48.21)% and trimethoprim sulfamethaxyl (7.14 and 19.64)% for each of them respectively.

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Section: Resistance Of S Mutans Isolates To Antibioticsmentioning

confidence: 99%

Isolation and Identification of Oral Bacteria and Characterization for biofilm formation and antibiotics resistance

ALI

2024

wjps

View full text Add to dashboard Cite

show abstract

Antimicrobial Peptides Targeting Streptococcus mutans: Current Research on Design, Screening and Efficacy

Cited by 1 publication

References 100 publications

Isolation and Identification of Oral Bacteria and Characterization for biofilm formation and antibiotics resistance

Isolation and Identification of Oral Bacteria and Characterization for biofilm formation and antibiotics resistance

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