2017
DOI: 10.1080/13880209.2017.1355926
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Abstract: Context:Croton sp. are plants with a well-reported antimicrobial activity. Croton limae A.P. Gomes, M.F. Sales P.E. Berry (Euphorbiaceae), known as ‘marmeleiro-prateado’, is commonly used to manage abdominal pain in Brazil.Objective: This work evaluates the phytochemical composition, antimicrobial and modulatory activities of the essential oil of C. limae leaves (EOCL).Materials and methods: The minimum inhibitory concentration (MIC) and the modulation of the antibiotic activity were determined using a microdi… Show more

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Cited by 15 publications
(8 citation statements)
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“…Accordingly, different classes of natural products have been shown to be able to modulate resistance to azoles [ 67 ]. The present study demonstrated the modulating effects of the ethanolic extract of C. heliotropiifolius roots, corroborating previous work that found similar effects for plants of the same genus against Candida strains [ 69 , 70 ].…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…Accordingly, different classes of natural products have been shown to be able to modulate resistance to azoles [ 67 ]. The present study demonstrated the modulating effects of the ethanolic extract of C. heliotropiifolius roots, corroborating previous work that found similar effects for plants of the same genus against Candida strains [ 69 , 70 ].…”
Section: Discussionsupporting
confidence: 92%
“…Based on previous studies, it is reasonable to assume that this effect may be due to the presence of components such as carboxylic acids, terpenes [ 55 , 58 ], and phenolic compounds [ 69 ]. However, further research is required to investigate the action of isolated compounds.…”
Section: Discussionmentioning
confidence: 99%
“…Similarly to what observed by Pinheiro et al [2], HP-β-CD showed an endothermic peak ( Figure 6B) with Tonset = 37.25 °C (ΔH = 6.47 J/g and Tpeak = 37.05 °C) related to water release from its β-CD exhibited an endothermic peak ( Figure 6A) involving ∆H = 231.02 J/g with Tonset = 30.94 • C and Tpeak = 73.71 • C, likely due to water release from its cavity, and a second event occurred at Tonset = 223.50 • C (∆H = 0.75 J/g and Tpeak = 226.68 • C), similarly to the observations of Nascimento et al [3]. It was not possible to identify eventual endothermic events related to β-CD mass loss at high temperatures [2,40] because a maximum temperature of 300 • C was set in this study. β-CD complexes obtained by KND and SL showed similar behavior ( Figure 6A) with Tonset = 27.07 • C (∆H = 48.46 J/g and Tpeak = 42.72 • C) and 24.07 • C (∆H = 142.10 J/g and Tpeak = 48.86 • C), respectively, both related to dehydration, but occurring at lower temperatures when compared to β-CD.…”
Section: Differential Scanning Calorimetry (Dsc)mentioning
confidence: 77%
“…Studies show that natural products without antibacterial activity can potentiate the effect of certain antibiotics, which is known as synergism [19]. The C. ceanothifolius essential oil is characterized by the presence of bicyclogermacrene, germacrene D and caryophyllene sesquiterpenes as major compounds (Table 1).…”
Section: Resultsmentioning
confidence: 99%