Antimicrobial Irrigants in the Endodontic Therapy

Iqbal, Azhar

doi:10.12816/0005998

Cited by 47 publications

(41 citation statements)

References 16 publications

(36 reference statements)

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“…Initial etiologic factor in formation of pulp waste and priapical bacteria were studied (Kandaswamy and Venkateshbabu 2010;Guerreiro-Tanomaru et al, 2011;Martin 1991;Mohammadi andAbbott 2009, Portenier et al, 2002). Micro-organisms may be existed in root canal, dentinal tubules, secondary canals and apical strait (Kandaswamy and Venkateshbabu 2010;Baumgartner et al, 2007;Iqbal 2012). In some dentinal teeth, even DEJ was infected (Zehnder et al, 2003).…”

Section: Resultsmentioning

confidence: 99%

“…The best result is obtained from using a good detergent with anti-bacterial activity when it contacts long enough with batteries of root canal system. This means that, for fulfi lling preparation stage before obtuaration, detergent needs to be reached a suffi cient volume during the treatment (Iqbal 2012). It seems that using local medicine is more effective and better that all applicable antibiotic plans (Martin 1991).…”

Section: Bioscience Biotechnology Research Communications Evaluation mentioning

confidence: 99%

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Evaluation of tissue dissolution ability of modifi ed chlorhexidine as a root canal irrigant

Shahsiah

Azizi

Moghimipour

et al. 2017

Biosci. Biotech. Res. Comm

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The fi rst and main goal of root canal treatment is the elimination of microorganisms from the contaminated root canal system and providing an environment for the healing of periapical tissues. Instrumentation alone cannoteffectivelyclean the complex root canal system. Souse of irrigantsalong mechanicalpreparationis required. But no single solution is able to fulfi ll these actions completely. Chlorhexidineis one of the substances thatis usedas anirrigantin endodontics. It has broadantimicrobialspectrum, but itdoes not have theability todissolveorganictissues. It has been shownthat theaddition ofsurfactantin thesolution can increasesthe abilityof dissolvetissue.In this in vitro study tissue-dissolving capacity of sodium hypochlorite (5/25% and 2/5%), chlorhexidine (0/2%) and modifi ed chlorhexidine (chlorhexidine + benzalkonium chloride and chlorhexidine + sodium lauryl solphate) were compared.Tissue samples prepared from bovine pulp and each of the samples immersed for 20 minutes in each test solution (changing the solution every 2 minutes).The sampleswereweighedbefore and aftertesting. The weight difference divided by the initial weight of the tissue sample, multiplied by 100, was defi ned as the percentage of tissue solubility.NaOCl 5/25% was more solublethantheothersolutions. ExceptCHX 0/2% and salineno statistically signifi cant differences was found between the tissuedissolving properties of othersolutions and NaOCl 5/25%.The results of this study indicate that the use of 0/2%CHX+2%SLS as irrigant in endodontic can show similar effect with NaOCl 5/25% in the solubility.

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Section: Resultsmentioning

confidence: 99%

Section: Bioscience Biotechnology Research Communications Evaluation mentioning

confidence: 99%

Evaluation of tissue dissolution ability of modifi ed chlorhexidine as a root canal irrigant

Shahsiah

Azizi

Moghimipour

et al. 2017

Biosci. Biotech. Res. Comm

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“…[8] Calcium hydroxide's anti microbial action is influenced by the speed of its dissociation into calcium ions and hydroxyl ions and by inactivating enzymes of the cytoplasmic membrane of microorganisms, thus causing toxic effects on the bacterial cells; another mechanism of action of this medication is its ability to absorb carbon dioxide, thus leading to the death of CO 2 - dependent bacteria. Chlorhexine may also present residual antimicrobial activity on the dentine surface after prolonged contact within root canal and also improve antimicrobial efficacy against calcium hydroxide resistant microorganisms.…”

Section: Discussionmentioning

confidence: 99%

Nonsurgical endodontic therapy along with minimal invasive treatment utilizing Bhasker's hypothesis for the management of infected radicular cystic lesion: A rare case report

et al. 2016

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Radicular cyst (RC) is the most common odontogenic cyst of inflammatory origin affecting the jaws; involves the roots of the carious or traumatic non-vital tooth. Different therapeutic modalities, such as nonsurgical endodontic therapy or surgical enucleation with primary closure, decompression etc., were proposed for the management of such lesions. Presenting a case of a 28-year-old otherwise healthy male patient who reported with pain and swelling with respect to tooth #41, 31. Diagnosis of infected RC at a rare location was established on the basis of clinical, radiographical and fine needle aspiration cytological examination. Looking after the clinical characteristics, origin, extension, size of cystic lesion and patient cooperation; nonsurgical endodontic therapy utilizing Bhasker's hypothesis was opted. One year post-operative result suggested that nonsurgical endodontic therapy along with minimally invasive treatment utilizing Bhasker's hypothesis is an effective tool to transform infected radicular cystic lesion to healthy periapical periodontal tissue.

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“…Rossi-Fedele., et al [46] showed Sterilox not being as effective as NaOCl and again a small study of 15 roots were used in carrying out the study. PAD was mentioned by Iqbal [48] which is an irrigation method involving a solution which can bind to bacteria and then treatment with a laser to irradiate bacteria. It offers advantages of low toxicity however the authors suggested there is no robust evidence to supportthe use of this system.…”

Section: World Journal Of Pharmacy and Pharmaceutical Sciencesmentioning

confidence: 99%

Update on Root Canal Irrigants

Panwar¹

2017

WJPPS

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Irrigation plays a pivotal role in the success of endodontic treatment in eradicating microbes and tissue material from the root canal system.There are currently a variety of differing protocols with regards to the irrigant selection and this review article covers the irrigants currently used and covers the associated evidence base for their usage. Sodium Hypochlorite is widely used as the most common irrigant in endodontics because of the tissue dissolving capability and also hypochlorite having an effective antimicrobial action. The action of Chlorhexidine has been reviewed as an alternative irrigant as it has a longer antimicrobial action due to its substantivity. However, the limitation of tissue solvent activity has meant its use is more common in retreatment cases. Chelating agents such as EDTA are now routinely used for removal of the smear layer and this article considers the literature on this and also to compare the combined regimens of endodontic irrigants with MTAD. Some alternative contemporary irrigants are also highlighted and discussed.

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Antimicrobial Irrigants in the Endodontic Therapy

Cited by 47 publications

References 16 publications

Evaluation of tissue dissolution ability of modifi ed chlorhexidine as a root canal irrigant

Evaluation of tissue dissolution ability of modifi ed chlorhexidine as a root canal irrigant

Nonsurgical endodontic therapy along with minimal invasive treatment utilizing Bhasker's hypothesis for the management of infected radicular cystic lesion: A rare case report

Update on Root Canal Irrigants

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