volume 1, issue 2, P115-123 2010
DOI: 10.5155/eurjchem.1.2.115-123.56
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Abstract: KEYWORDSNew derivatives of thieno [2,3-d]pyrimidin-4-one, 4ac, and 6 were respectively synthezised based on thiophene derivative, 2c, bearing ortho-disposed amino and ester groups. Carbohydrazide, 7, was obtained by hydrazinolysis of 3-ethoxycabonylmethyl derivative, 4c. Compounds 4b and 7 were used to build up two series of novel 3-substitutedmethylthieno[2,3-d]pyrimidin-4-ones, 711, and their corresponding 3-substituted-amino analogues 12, 15a,b, 18, which were of significant interest for biological study. …

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