Antimicrobial effect of MTAD, Tetraclean, Cloreximid, and sodium hypochlorite on three common endodontic pathogens

Giardino, Luciano; Savoldi, E; Ambu, Emanuele; Rimondini, Roberto; Palezona, Alberto; Debbia, Eugenio A.

doi:10.4103/0970-9290.57353

Cited by 16 publications

(13 citation statements)

References 27 publications

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“…In another study, Khademi et al (13) found the antibacterial substantivity of 2.6% NaOCl was significantly lesser than 2% CHX and 100 mg /ml doxycycline. Giardino et al (22) revealed that MTAD and Tetraclean induced the largest zone of microbial inhibition of E. faecalis cultured under both aerobic and anaerobic conditions, when compared with NaOCl which is in accordance to the findings of the present study. Another thing concerning the substantivity of root canal irrigants is the time of dentin treatment to induce substantivity.…”

Section: Discussionsupporting

confidence: 82%

Residual antibacterial activity of a new modified sodium hypochlorite-based endodontic irrigation solution

Mohammadi¹,

Mombeinipour²,

Giardino³

et al. 2011

Med Oral

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Objective: In this in vitro study the antibacterial substantivity of a new sodium hypochlorite-based root canal irrigant (Hypoclean) in bovine root dentin was investigated. Study Design: Ninety dentin tubes prepared from bovine incisor teeth were used. After contamination for 14 days with Enterococcus faecalis, the specimens were divided into five groups as follows: Hypoclean; Tetraclean; 5.25% sodium hypochlorite (NaOCl); infected dentin tubes (positive control); and sterile dentin tubes (negative control). Dentin chips were collected with round burs into tryptic soy broth and after culturing, the number of colony-forming units (CFU) was counted. Results: The number of CFU was minimum in the first cultures in all experimental groups, and the results obtained were significantly different from each other at any time period (P < 0.05). At all five experimental periods, the Tetraclean group showed the most effective antibacterial action (P < 0.05). Regular 5.25% NaOCl group showed the worst result at all periods. Hypoclean group demonstrated no bacterial growth after treatment. In each group, the number of CFU increased significantly by time-lapse (P < 0.05). Conclusion: The residual antibacterial activity of Tetraclean was significantly greater than Hypoclean and 5.25% NaOCl.

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Section: Discussionsupporting

confidence: 82%

Residual antibacterial activity of a new modified sodium hypochlorite-based endodontic irrigation solution

Mohammadi¹,

Mombeinipour²,

Giardino³

et al. 2011

Med Oral

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“…In another study, Giardino et al . (26) revealed that MTAD and Tetraclean induced the largest zone of microbial inhibition of E. faecalis cultured under both aerobic and anaerobic conditions, when compared with NaOCl, which is in accordance to the findings of the present study.…”

Section: Discussionsupporting

confidence: 92%

Antibacterial substantivity of a new antibiotic‐based endodontic irrigation solution

2010

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The aim of this study was to evaluate the residual antibacterial activity of Tetraclean, MTAD and 5.25% sodium hypochlorite (NaOCl) in bovine root dentin in vitro. One hundred and ten dentin tubes prepared from bovine incisor teeth were infected in vitro for 14 days with Enterococcus faecalis. Thereafter, the specimens were divided into five groups as follows: Tetraclean; MTAD; 5.25% NaOCl; infected dentin tubes (positive control); and sterile dentin tubes (negative control). Dentin chips were collected using round burs into tryptic soy broth and after culturing, the number of colony-forming units (CFU) was counted. The number of CFU in all experimental groups was minimum after treatment, and the results obtained were significantly different from each other at any time period (P < 0.05). The Tetraclean group showed the most effective antibacterial action at all five experimental periods (P < 0.05). MTAD group showed the least antibacterial activity after treatment. However, at days 7, 14, 21 and 28 MTAD showed more effective antibacterial action than NaOCl. In each group, the number of CFU increased significantly by time-lapse (P < 0.05). In conclusion, the residual antibacterial activity of Tetraclean was significantly greater than MTAD and 5.25% NaOCl.

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“…CTR is also present in other irrigants such as Tetraclean (Ogna Laboratori Farmaceutici, Muggio, Italy) (Giardino et al . ), Hypoclean (Palazzi et al . ) and SmearClear (da Silva et al .…”

Section: Introductionmentioning

confidence: 99%

“…QMiX demonstrated stronger antibacterial action than CHX after 1 min of contact with E. faecalis biofilm (Stojicic et al 2012). CTR is also present in other irrigants such as Tetraclean (Ogna Laboratori Farmaceutici, Muggio, Italy) (Giardino et al 2009), Hypoclean (Palazzi et al 2011) andSmearClear (da Silva et al 2008 (Pappen et al 2010).…”

Section: Introductionmentioning

confidence: 99%

Antibiofilm activity of irrigating solutions associated with cetrimide. Confocal laser scanning microscopy

et al. 2014

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Antimicrobial effect of MTAD, Tetraclean, Cloreximid, and sodium hypochlorite on three common endodontic pathogens

Cited by 16 publications

References 27 publications

Residual antibacterial activity of a new modified sodium hypochlorite-based endodontic irrigation solution

Residual antibacterial activity of a new modified sodium hypochlorite-based endodontic irrigation solution

Antibacterial substantivity of a new antibiotic‐based endodontic irrigation solution

Antibiofilm activity of irrigating solutions associated with cetrimide. Confocal laser scanning microscopy

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