Antimicrobial effect of<i>Helichrysum plicatum</i>subsp.<i>plicatum</i>

Demir, Aysel Elik; Taban, Birce Mercanoğlu; Aslan, Mustafa; Yeşilada, Erdem; Aytaç, S. A.

doi:10.1080/13880200802590434

Cited by 12 publications

(5 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There are several studies on H. plicatum antimicrobial activity, which was ascribed to the phenolic and flavonoid contents [13,120,122]. Fungi were more sensitive to H. plicatum extracts than bacteria, which corroborates our findings.…”

Section: Antimicrobial Activitysupporting

confidence: 90%

Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts

Vujić

Vidaković

Jadranin

et al. 2020

Plants

View full text Add to dashboard Cite

Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.

show abstract

Section: Antimicrobial Activitysupporting

confidence: 90%

Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts

Vujić

Vidaković

Jadranin

et al. 2020

Plants

View full text Add to dashboard Cite

show abstract

“…It is known that extracts of H. plicatum have remarkable antioxidant, antimicrobial, and cytotoxic activities (Demir et al 2009;Tatlı et al 2009;Apaydın Yıldırım et al 2017;Taşkın et al 2020). In the literature, it is reported that the composition of H. plicatum is rich in flavonoids (Kulevanova et al 2000;Acet et al 2019;Güneş et al 2019).…”

Section: Discussionmentioning

confidence: 99%

IN VITRO STUDY ON ANTIMICROBIAL AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACT of Helichrysum plicatum subsp. polyphyllum (Asteraceae)

DURAN

Kiliç

Tanrıkulu

et al. 2023

Sabuncuoglu Serefeddin Health Sciences

View full text Add to dashboard Cite

Helichrysum plicatum subsp. polyphyllum (H. plicatum), is an important species belonging to the family Acteraceae, which is used in alternative medicine. For this reason, it was aimed to determine the antimicrobial and cytotoxic activity of H. plicatum extract in this study. Firstly, H. plicatum was extracted with methanol for 6 hours using a Soxhlet. Secondly, the antimicrobial activity of the extract was tested against Gram-positive (Staphylococcus aureus ATCC®25923, Bacillus cereus ATCC®7064, Bacillus subtilis ATCC®6633) and Gram-negative (Escherichia coli ATCC®25922, Klebsiella pneumoniae ATCC®706003, Salmonella Enteritidis ATCC®13076) bacteria and a yeast (Candida albicans ATCC®10231) using well diffusion and microdilution methods. Finally, the cytotoxic activity of H. plicatum extract on DLD-1 (human colon adenocarcinoma) and CCD-18Co (normal colon) cell lines was determined by MTT method. According to the results of the antimicrobial effect, H. plicatum extract was found to have a stronger antibacterial activity against Salmonella Enteritidis (24.13±1.15 and 156µg/mL) among Gram-negative bacteria. It was determined to have inhibitory activity against also Bacillus cereus (16.66±1.52 and 312µg/mL) among Gram-positive bacteria. In addition, the extract showed a strong antifungal effect on Candida albicans (22.66±0.57 and 312µg/mL). In addition, the H. plicatum extract did not show any cytotoxic effect on CCD-18Co cells, while the IC50 value on the DLD-1 cell line was determined as 8.17mg/mL. This indicates that the plant extract has a selective toxic effect on cancer cells. These results reveal that H. plicatum has the potential to be used for therapeutic purposes after being supported by further studies.

show abstract

“…As an example, essential oils (EOs) of aromatic plants are applied as a part of a hurdle technology in which several food preservation factors are combined to provide microbial stability of the food products (Calo et al, 2015). For this reason, extracts and EOs of aromatic plants, with many originating from the Mediterranean area, found a great place as new-generation natural compounds in food production and human health with proven benefits (Demir et al, 2009;Christaki et al, 2012). Additionally, they have started to be used in animal nutrition as alternatives to antibiotics, especially after the ban of antibiotic feed additives within the European Union countries in 2006, to improve their productivity and hence the properties of the resulting animalderived foods (Christaki et al, 2012;Giannenas et al, 2013;Socaci et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Value-added effects of using aromatic plants in foods and human therapy

et al. 2022

View full text Add to dashboard Cite

Consumers' demands for low-processed and healthier food products led to a search for alternatives to replace or reduce synthetic food additives with natural ones. Aromatic plant derivatives which have GRAS status, have been examined for being natural food preservatives and antioxidants to prolong the shelf-life of foods. They contribute to food safety, owing to their anti-quorum sensing, and anti-biofilm properties. These potential food safety attributes and increasing demand for natural food additive options have led to an interest in the use of them, especially in traditional meat, dairy, and bakery products, which would provide them an added value, and increase the market competitiveness. Therefore, the overall perspective of the value-added effects of using aromatic plants and their derivatives in food production and of their incorporated use into packaging materials for active packaging are discussed in this review. In addition, it provides information on their antimicrobial and antioxidant actions. The review also aims to give detailed information on benefits of vegetal bioactive compounds in health and disease by giving their nutraceutical and health-promoting properties. The current knowledge on their application in the treatment of health disorders is presented, their ability to prevent diseases is discussed, and the areas for future research are proposed.

show abstract

Antimicrobial effect ofHelichrysum plicatumsubsp.plicatum

Cited by 12 publications

References 26 publications

Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts

Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts

IN VITRO STUDY ON ANTIMICROBIAL AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACT of Helichrysum plicatum subsp. polyphyllum (Asteraceae)

Value-added effects of using aromatic plants in foods and human therapy

Contact Info

Product

Resources

About