Antimicrobial drug resistance in isolates of Salmonella enterica from cases of salmonellosis in humans in Europe in 2000: results of international multi-centre surveillance

Abstract

The Enter-net surveillance system received results of antimicrobial sensitivity tests for isolates from over 27 000 cases of human salmonellosis in 2000 in 10 European countries. Almost 40% of isolates were resistant to at least one antimicrobial, with 18% multiresistant. Resistance to ampicillin, streptomycin, sulphonamides and tetracyclines was common, with over 20% of isolates resistant to at least one of these antimicrobials. Clinical resistance to ciprofloxacin was rare, with only 0.5% of isolates exhibiting such resistance (MIC >1.0 mg/l). Resistance to nalidixic acid coupled with a decreased susceptibility to ciprofloxacin (MIC 0.25-1.0 mg/l) was more common, with 14% of isolates showing these properties. Resistance to third-generation cephalosporins was rare with only 0.6% of isolates resistant to cefotaxime. In all countries multiple resistance was most common in Salmonella enterica serotype Typhimurium, with 51% of isolates multiresistant in total. In England and Wales multiple resistance was also prevalent in S. Virchow and S. Hadar, whereas in other countries multiple resistance was common in serotypes such as S. Blockley.

Characterization of Salmonella enterica Serotype Typhimurium Isolates from Human, Food, and Animal Sources in the Republic of Ireland

“…Escherichia coli ATCC 25922 was used as a control on each test occasion. An isolate was defined as being drug resistant if it was resistant to at least one of the tested antimicrobial agents and multidrug resistant if it was resistant to four or more of the antimicrobial agents tested (25). Phage typing based on the Colindale method (1) was carried out in the Salmonella Reference Laboratory, Galway, Ireland.…”

Antibiotic Resistance Among Salmonella spp. Isolated from Feces of Patients with Acute Diarrhea in Gwangju Area, Korea, during 2000-2009

“…Resistance of S. Enteritidis to antibiotics such as ampicillin, chloramphenicol, tetracycline, and nalidixic acid has also been reported from other countries such as Brazil (Fernandes et al, 2003) and Turkey (Erdem et al, 2005), although the prevalence of the studies varied. S. Enteritidis isolated from 27,000 cases of human salmonellosis in 2000 in 10 European countries also showed the highest rate of resistance to nalidixic acid, followed by streptomycin and ampicillin (Threlfall et al, 2003).…”

Effets De <i>Thonningia sanguinea</i> (Thos) Sur La Qualite Des Oeufs Et Le Taux De Ponte Des Poules Au Cours D\'une Salmonellose Experimentale A <i>Salmonella enterica</i> Serotype Enteritidis Lysotype 6

“…Le contrôle de ces salmonelloses repose essentiellement sur une antibiothérapie. Cependant, certaines souches de salmonelles se montrent résistantes à plusieurs classes d'antibiotiques par l'acquisition de plasmides codant pour des résistances multiples (Gado et al, 1998 ;Threfall et al, 2003 ). Parmi ces souches multirésistantes figure Salmonella enterica serotype Enteritidis lysotype 6 (Dosso, 1998).…”