2019
DOI: 10.25083/rbl/24.6/1111.1119
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Antimicrobial compounds of the genus Bacillus: A review

Abstract: Antibiotics are low molecular-weight molecules produced as secondary metabolites, mainly by microorganisms that live in the soil. Microbial secondary metabolites have been a major source of clinically useful antibiotics. Members of the genus Bacillus are known to produce a wide arsenal of antimicrobial substances, including peptide and lipopeptide antibiotics. These peptides can be classified into two different groups based on whether they are ribosomally (bacteriocins) or nonribosomally (polymyxins and iturin… Show more

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Cited by 30 publications
(19 citation statements)
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“…At the same time, members of this family are an important source for producing a wide range of structurally diverse antimicrobial substances with rapid kill activity against various pathogens (Zhao et al, 2018). Antibiotics, which constitute an important part of antimicrobial substances, are mainly produced by microorganisms living in the soil (Stoica et al, 2019). For this purpose, the antimicrobial effect of twenty isolates in the Bacillaceae family isolated from the soil was investigated against various pathogenic bacteria.…”
Section: Discussionmentioning
confidence: 99%
“…At the same time, members of this family are an important source for producing a wide range of structurally diverse antimicrobial substances with rapid kill activity against various pathogens (Zhao et al, 2018). Antibiotics, which constitute an important part of antimicrobial substances, are mainly produced by microorganisms living in the soil (Stoica et al, 2019). For this purpose, the antimicrobial effect of twenty isolates in the Bacillaceae family isolated from the soil was investigated against various pathogenic bacteria.…”
Section: Discussionmentioning
confidence: 99%
“…Their structure confers an amphiphilic character, making them capable of interacting with cell membranes and the vanilloid receptors of the nervous system. [40][41][42] Approximately 25 different natural capsaicinoids have been recorded. 43 Among them, capsaicin and dihydrocapsaicin are considered the major ones, comprising from 89 to 98% of the total CAPS concentration in Capsicum fruits.…”
Section: The Genus Capsicummentioning
confidence: 99%
“…Bacitracin is the first peptide antibiotic derived from cultures of B. licheniformis and has been applied widely in the medical and veterinary area with excellent safety. This antibiotic is a mixture of at least 5 polypeptides, and consists of 3 separate compounds, bacitracin A, B and C. It is active against various species of Gram-positive and a few species of Gram-negative bacteria [ 16 , 17 ]. In addition to that, some strains can produce two-peptide lantibiotic bacteriocin lichenicidin [ 18 ]; however, synthesis of bacteriocin-like peptides such as lichenin and bacillocin was also reported [ 13 ].…”
Section: Introductionmentioning
confidence: 99%