Antimicrobial compounds from endophytic Streptomyces sp. BCC72023 isolated from rice (Oryza sativa L.)

Supong, Khomsan; Thawai, Chitti; Choowong, Wilunda; Kittiwongwattana, Chokchai; Thanaboripat, Dusanee; Laosinwattana, C.; Koohakan, Prommart; Parinthawong, Nonglak; Pittayakhajonwut, Pattama

doi:10.1016/j.resmic.2016.01.004

Cited by 38 publications

(23 citation statements)

References 45 publications

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“…Their ecological niche as endophytes is mostly as biocontrol agents that produce antimicrobial substances to inhibit other microorganisms ( 15 ). They have biotechnological potential as an important source of bioactive secondary metabolites, such as antimicrobials ( 44 ). Asteroleplasma ( Anaeroplasmataceae , Anaeroplasmatales, Mollicutes), a strict anaerobic anaeroplasma, was also found inside the roots.…”

Section: Discussionmentioning

confidence: 99%

Bacterial Communities Associated with Different <i>Anthurium andraeanum</i> L. Plant Tissues

Sarria-Guzmán

Chávez-Romero

Gómez-Acata

et al. 2016

Microbes and environments

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Plant-associated microbes have specific beneficial functions and are considered key drivers for plant health. The bacterial community structure of healthy Anthurium andraeanum L. plants was studied by 16S rRNA gene pyrosequencing associated with different plant parts and the rhizosphere. A limited number of bacterial taxa, i.e., Sinorhizobium, Fimbriimonadales, and Gammaproteobacteria HTCC2089 were enriched in the A. andraeanum rhizosphere. Endophytes were more diverse in the roots than in the shoots, whereas all shoot endophytes were found in the roots. Streptomyces, Flavobacterium succinicans, and Asteroleplasma were only found in the roots, Variovorax paradoxus only in the stem, and Fimbriimonas 97%-OTUs only in the spathe, i.e., considered specialists, while Brevibacillus, Lachnospiraceae, Pseudomonas, and Pseudomonas pseudoalcaligenes were generalist and colonized all plant parts. The anaerobic diazotrophic bacteria Lachnospiraceae, Clostridium sp., and Clostridium bifermentans colonized the shoot system. Phylotypes belonging to Pseudomonas were detected in the rhizosphere and in the substrate (an equiproportional mixture of soil, cow manure, and peat), and dominated the endosphere. Pseudomonas included nine 97%-OTUs with different patterns of distribution and phylogenetic affiliations with different species. P. pseudoalcaligenes and P. putida dominated the shoots, but were also found in the roots and rhizosphere. P. fluorescens was present in all plant parts, while P. resinovorans, P. denitrificans, P. aeruginosa, and P. stutzeri were only detected in the substrate and rhizosphere. The composition of plant-associated bacterial communities is generally considered to be suitable as an indicator of plant health.

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Section: Discussionmentioning

confidence: 99%

Bacterial Communities Associated with Different <i>Anthurium andraeanum</i> L. Plant Tissues

Sarria-Guzmán

Chávez-Romero

Gómez-Acata

et al. 2016

Microbes and environments

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“…Among the microorganisms that produce bioactive compounds, those of the Actinomycetales family stand out, especially Streptomyces spp., which is known for its ability to produce substances with several antimicrobial, antimalarial, and antitumor actions ( Supong et al, 2016 ; Elkhayat and Goda, 2017 ; Bunbamrung et al, 2020 ; Mahmood and Kataoka, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Potential of Streptomyces ansochromogenes (PB3) Isolated From a Plant Native to the Amazon Against Pseudomonas aeruginosa

et al. 2020

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The objective of this study was to evaluate the antibacterial action of filamentous bacteria isolated from the Byrsonima crassifolia leaf. An endophytic bacterium has been identified by classical and molecular techniques as Streptomyces ansochromogene . Screening for antibacterial action against pathogens with medical relevance ( Klebsiella pneumoniae ATCC 700603, Pseudomonas aeruginosa ATCC 15692, Staphylococcus aureus ATCC 6538, Corynebacterium diphtheriae ATCC 27012, Mycobacterium abscessus , Cryptococcus gattii ATCC 24065, and Cryptococcus neoformans ATCC 24067) demonstrated activity against the bacterium P. aeruginosa ATCC 0030 with inhibition diameter zones (IDZ) of 17.6 ± 0.25 mm in the preliminary screening in solid medium. After fermentation in liquid medium, an IDZ of 19.6 ± 0.46 mm and a minimum inhibitory concentration (MIC) of 0.5 mg/mL were detected. The antibiofilm action was observed with 100% inhibition of biofilm formation at a concentration of 0.250 mg/mL. When the infection curve was prepared, it was observed that the metabolite was effective in protecting the larvae of Tenebrio molitor . The metabolite does not show toxicity for eukaryotic cells. The leishmanicidal activity demonstrated that the metabolite presented a dose-dependent effect on the promastigotes forms of Leishmania amazonensis growth and the estimated IC 50 /72 h was 71.65 ± 7.4 μg/mL. Therefore, it can be concluded that the metabolite produced by the endophytic bacterium Streptomyces sp. is promising for future use as an alternative strategy against bacterial resistance.

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“…We therefore revisited these highly antifungal metabolite extracts and conducted detailed activity- and NMR-guided fractionations (Romero et al, 2015). These intensified efforts led to the isolation and characterization of two new elaiophylin derivatives, carrying an unsaturated enone moiety, which we named efomycins K ( 1 ) and L ( 2 ), in addition to the known derivative efomycin M ( 3 ) (Figure 1), a potent and specific inhibitor of selectin (Schön et al, 2002; Supong et al, 2016). Further studies led to the isolation of five known and structurally-related hemiketal derivatives, including efomycin G ( 4 ) (Frobel et al, 1990), elaiophylin ( 5 ) (Kaiser and Keller-Schierlein, 1981; Ritzau et al, 1998; Wu et al, 2013), 11- O -methylelaiophylin ( 6 ) (Wu et al, 2013), and 11,11’- O -dimethylelaiophylin ( 7 ) (Kretschmer et al, 1985; Pimentel-Elardo et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Efomycins K and L From a Termite-Associated Streptomyces sp. M56 and Their Putative Biosynthetic Origin

et al. 2019

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Two new elaiophylin derivatives, efomycins K ( 1 ) and L ( 2 ), and five known elaiophylin derivatives ( 3–7 ) were isolated from the termite-associated Streptomyces sp. M56. The structures were determined by 1D and 2D NMR and HR-ESIMS analyses and comparative CD spectroscopy. The putative gene cluster responsible for the production of the elaiophylin and efomycin derivatives was identified based on significant homology to related clusters. Phylogenetic analysis of gene cluster domains was used to provide a biosynthetic rational for these new derivatives and to demonstrate how a single biosynthetic pathway can produce diverse structures.

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Antimicrobial compounds from endophytic Streptomyces sp. BCC72023 isolated from rice (Oryza sativa L.)

Cited by 38 publications

References 45 publications

Bacterial Communities Associated with Different <i>Anthurium andraeanum</i> L. Plant Tissues

Bacterial Communities Associated with Different <i>Anthurium andraeanum</i> L. Plant Tissues

Antimicrobial Potential of Streptomyces ansochromogenes (PB3) Isolated From a Plant Native to the Amazon Against Pseudomonas aeruginosa

Efomycins K and L From a Termite-Associated Streptomyces sp. M56 and Their Putative Biosynthetic Origin

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