Antimicrobial, anticancer, and antioxidant potential of two dominant macro-lichen Dirinaria aegialita and Parmotrema praesorediosum collected from Similipal Biosphere Reserve of Odisha, India

Pradhan, Srimay; Upreti, D. K.; Meher, Rajesh Kumar; Satapathy, Kunja Bihari

doi:10.7324/jabb.2022.100604

Cited by 2 publications

(2 citation statements)

References 52 publications

(52 reference statements)

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“…3) 1 H-NMR (TMS, DMSO, 500 MHz, δ, ppm) 1.76 (3H, s); 2.10 (3H, s); 2.66 (3H, s); 2.68 (3H, s); 5.98 (1H, s); 11.04 (1H, s); 13.32 (1H, s) (Fig. 4b) 13 C-NMR 13 the potential as an anticancer 23,40,41) .…”

Section: Spectrometer Spectrummentioning

confidence: 99%

Antioxidant Activity of Usnic Acid Compound from Methanol Extract of Lichen <i>Usnea</i> sp.

et al. 2023

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IntroductionIndonesia has abundant natural resources so it is known as a mega biodiversity country. The wealth of natural resources has the potential to be used as raw materials for medicines or traditional medicines. Traditional medicine is part of the culture and has been used for centuries. Currently, public confidence in the use of traditional medicine is getting higher seeing the effectiveness of the treatment produced 1,2) . Plants or products obtained from nature are preferred to be developed as pharmaceutical raw materials because of their high content of secondary metabolites 3,4) . Many natural materials are targeted in the manufacture of medicines, one of the raw materials that have the potential to be developed is crustal lichen organisms. Like plants, lichen has also been used in treating many ailments due to its medicinal properties since ancient times. Therefore lichen can also be used to develop new pharmaceutical products 5,6) .Lichen is a medicinal plant that is classified as a unique and low organism and more than 250 chemical compounds

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Section: Spectrometer Spectrummentioning

confidence: 99%

Antioxidant Activity of Usnic Acid Compound from Methanol Extract of Lichen <i>Usnea</i> sp.

et al. 2023

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“…The morphology of cells was used to identify apoptotic cells (e.g. nuclear condensation), membrane bleb development, and apoptotic bodies, in comparison to untreated cells (Meher et al, 2021a;Pradhan et al, 2022).…”

Section: Anticancer Evaluation By Using Mcf-7 and Mdamb-231 Cell Linesmentioning

confidence: 99%

Induction of apoptosis on breast adenocarcinoma and suppression of pathogenic bacterial growth by antioxidant rich tuber extract of Dioscorea Bulbifera

Induar

Meher

Dubey

et al. 2022

AUDJG - Food Technology

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Nature derived product drew a lot of interest because of their potential nutritional and therapeutics value. Most natural compounds are now processed and developed as possible antioxidative, antimitotic, antimicrobial, anti-inflammatory, antiangiogenic, and anti-carcinogenic pharmaceutical agents. Indeed, several natural products have been used as lead compounds in the development of most potent physiologically relevant chemicals for therapeutic application. In the current study antioxidant and anticancer potential of tuber extract of Dioscorea bulbifera have been determined as well as its antimicrobial potential against pathogenic bacteria. The IC50 value for the extract was found to be 55µg/ml for MCF-7 and 75µg/ml for MD-AMB-231 human breast cancer adenocarcinoma whereas minimum inhibitory concentration (MIC) value of the methanolic extract against S. aureus was 0.19 mg/ml and minimum bactericidal concentration (MBC) was 1.56 mg/ml. Further to identify compounds responsible for antioxidant, anticancer and antimicrobial activity GCMS analysis of the extract was conducted. Histopathological and haematological assay were carried out on animal model to identify any toxic effect of extract on vital organ system. This study may be used to provide the groundwork for the creation of novel nature-derived drugs whose biological activity can be determined by further purification, characterization, and validation of the active phytochemicals and their mechanism of action.

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Antimicrobial, anticancer, and antioxidant potential of two dominant macro-lichen Dirinaria aegialita and Parmotrema praesorediosum collected from Similipal Biosphere Reserve of Odisha, India

Cited by 2 publications

References 52 publications

Antioxidant Activity of Usnic Acid Compound from Methanol Extract of Lichen <i>Usnea</i> sp.

Antioxidant Activity of Usnic Acid Compound from Methanol Extract of Lichen <i>Usnea</i> sp.

Induction of apoptosis on breast adenocarcinoma and suppression of pathogenic bacterial growth by antioxidant rich tuber extract of Dioscorea Bulbifera

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