Antimicrobial, Antibiofilm and Cytotoxicity Activity of a New Acridine Hyperbranched Polymer in Solution and on Cotton Fabric

Vasileva−Tonkova, Evgenia; Staneva, Desislava; Medel, Sandra; Bosch, Paula; Grozdanov, Petar; Nikolova, Ivelina; Grabchev, Ivo

doi:10.1007/s12221-019-8687-4

Cited by 13 publications

(8 citation statements)

References 30 publications

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“…The Cu-complexes demonstrated slightly lower activity, compared to that of the ligands, and [Cu 8 (S2)] was found to be slightly less toxic than [Cu 3 (S1)] with CC 50 values of 234.2 μg/mL and 219.1 μg/mL, respectively. Polymer S1 is six times less toxic in comparison with the same polymer modified with 1,8-naphthalimide [ 18 ] and twice less toxic than the polymer modified with acridine [ 19 ].…”

Section: Resultsmentioning

confidence: 99%

“…Hyperbranched polymers modified with 1,8-naphthalimides [ 16 ] or acridine [ 17 ] units have shown very good sensor properties in detecting metal ions and protons. These polymers also exhibit promising antimicrobial activity [ 18 , 19 ]. Recently, in order to broaden the selection of fluorophores in the modification of polymers with potential bioactivity, hyperbranched polymers containing dansyl groups were synthesized and their photophysical characteristics were investigated [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

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Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies

et al. 2020

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Two new copper complexes of hyperbranched polymers modified with dansyl units were synthesized and characterized by infrared spectroscopy (IR) and electron paramagnetic resonance (EPR) techniques. It was found that copper ions coordinate predominantly with nitrogen or oxygen atoms of the polymer molecule. The place of the formation of complexes and the number of copper ions involved depend on the chemical structure of the polymer. The antimicrobial activity of the new polymers and their Cu(II) complexes was tested against Gram-negative and Gram-positive bacterial and fungal strains. Copper complexes were found to have activity better than that of the corresponding ligands. The deposition of the modified branched polymers onto cotton fabrics prevents the formation of bacterial biofilms, which indicates that the studied polymers can find application in antibacterial textiles.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies

et al. 2020

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“…Similarly, the gold nanoparticles containing fabrics negatively influenced the viability of developed biofilms of E. coli and S. aureus [ 44 ]. Cotton fabric treated with P1000-Acrid dendrimer also hindered the development of P. aeruginosa -biofilm [ 45 ]. These anti-biofilm fabrics do not allow the adhesion of bacterial cells to the fibers or kill the cells, which comes in closer contact via different mechanisms, thus do not allow the microbes to grow and develop a biofilm.…”

Section: Types Of Antimicrobial Textilesmentioning

confidence: 99%

Antimicrobial textile: recent developments and functional perspective

2021

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Antimicrobial textiles are functionally active textiles, which may kill the microorganisms or inhibit their growth. The present article explores the applications of different synthetic and natural antimicrobial compounds used to prepare antimicrobial textiles. Different types of antimicrobial textiles including: antibacterial, antifungal and antiviral have also been discussed. Different strategies and methods used for the detection of a textile's antimicrobial properties against bacterial and fungal pathogens as well as viral particles have also been highlighted. These antimicrobial textiles are used in a variety of applications ranging from households to commercial including air filters, food packaging, health care, hygiene, medical, sportswear, storage, ventilation and water purification systems. Public awareness on antimicrobial textiles and growth in commercial opportunities has been observed during past few years. Not only antimicrobial properties, but its durability along with the color, prints and designing are also important for fashionable clothing; thus, many commercial brands are now focusing on such type of materials. Overall, this article summarizes the scientific aspect dealing with different fabrics including natural or synthetic antimicrobial agents along with their current functional perspective and future opportunities.

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“…The highest antimicrobial activity effect of the HB(PDMA)s was attributed to HB(PDMA)G 4 with inhibition zones of 28-30 mm, 25 mm, and 27 mm for the G+Ve, G−Ve, and candida strains, respectively, with the lowest MICs/MBCs and MICs/MFCs ranging from 0.039-0.078/0.039-0.156 mM, 0.312/0.625 mM, and 0.312/0.312 mM for the Gram-positive, for Gram-negative bacterial strains and yeast strain, respectively in comparison to HB(PDMA)G 2 and HB(PDMA)G 3 ( Tables 2 and 3). This result may be attributed to the number of branching as well as the increase in the functional groups and the bio-permeability action (size and molecular weight or lipophilic groups) [45]. The predicted mechanism of the broad antibacterial activity of HB(PDMA)s G 2 , G 3 , and G 4 was related to the electrostatic interaction between the positively charged functional terminal-groups of HB(PDMA)s G 2 , G 3 , and G 4 structure and the negatively charged bacterial surface phospholipid [46,47].…”

Section: Applications Of the Synthesized Hb(pdma)smentioning

confidence: 99%

Progressive Applications of Hyperbranched Polymer Based on Diarylamine: Antimicrobial, Anti-Biofilm and Anti-Aerobic Corrosion

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New generations of hyperbranched aramids were synthesized from diarylamine and methyl acrylate using an AB2 monomer approach in a straightforward one-pot preparation. The chemical structure of hyperbranched Phenylenediamine/Methyl Acrylate HB(PDMA was confirmed by Fourier Transform Infrared (FTIR) and Nuclear Magnetic Resonance (1HNMR) spectroscopy. In addition, the particle’s size and distribution were recorded using Dynamic Light Scattering (DLS). Moreover, the synthesized HB(PDMA)s displayed broad-spectrum antimicrobial activities against Gram-positive and Gram-negative bacteria as well as yeast strains and anti-biofilm activity where the highest activity was attributed to HB(PDMA)G4 at the lowest Minimum Inhibitory, Minimum Bactericidal, and Fungicidal Concentrations (MIC, MBC, and MFC, respectively). Furthermore, the HB(PDMA)s expressed anti-bacterial activity against isolated Pseudomonas sp. (R301) at a salinity of 35,000 ppm (NaCl). In addition, they revealed different corrosion inhibition efficiencies at the cultivated medium salinity at the estimated minimum bactericidal concentrations. The highest metal corrosion inhibition efficiencies were 59.5 and 94.3% for HB(PDMA)G4 at the Minimum Bactericidal Concentrations (MBCs) and two times Minimum Bactericidal Concentrations (2XMBCs), respectively, in comparison to both negative and positive controls.

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Antimicrobial, Antibiofilm and Cytotoxicity Activity of a New Acridine Hyperbranched Polymer in Solution and on Cotton Fabric

Cited by 13 publications

References 30 publications

Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies

Hyperbranched Polymers Modified with Dansyl Units and Their Cu(II) Complexes. Bioactivity Studies

Antimicrobial textile: recent developments and functional perspective

Progressive Applications of Hyperbranched Polymer Based on Diarylamine: Antimicrobial, Anti-Biofilm and Anti-Aerobic Corrosion

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