Antimicrobial, Anti-Inflammatory, Antiparasitic, and Cytotoxic Activities of<i>Laennecia confusa</i>

Ruiz, María G. Martínez; Richard-Greenblatt, Melissa; Juárez, Zaida Nelly; Av‐Gay, Yossef; Bach, Horacio; Hernández, Lucina

doi:10.1100/2012/263572

Cited by 12 publications

(5 citation statements)

References 20 publications

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“…Plates were placed in a humidified atmosphere at 37°C supplemented with 5% CO 2 for 24 h. Untreated THP-1 cells and DMSO were used as negative controls, whereas 5% hydrogen peroxide was used as a positive control. Propidium iodide (PI) was used to evaluate membrane damage [18]. The half maximal inhibitory concentration (IC 50 ) was calculated by plotting the compound concentrations against the percentage of damaged cells.…”

Section: Methodsmentioning

confidence: 99%

Antimicrobial, Antiparasitic, Anti‐Inflammatory, and Cytotoxic Activities of Lopezia racemosa

Cruz-Paredes

Balbás

Gómez‐Velasco

et al. 2013

The Scientific World Journal

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The present study investigates the potential benefits of the Mexican medicinal plant Lopezia racemosa (Onagraceae). Extracts and fractions from aerial parts of this plant were assessed to determine their antibacterial, antifungal, antiparasitic, anti-inflammatory and cytotoxic activities in vitro. Aerial parts of the plant were extracted with various solvents and fractionated accordingly. Extracts and fractions were tested against a panel of nine bacterial and four fungal species. The antiparasitic activity was tested against Leishmania donovani, whereas the anti-inflammatory activity of the compounds was determined by measuring the secretion of interleukin-6 from human-derived macrophages. The same macrophage cell line was used to investigate the cytotoxicity of the compounds. Various extracts and fractions showed antibacterial, antifungal, antiparasitic, and anti-inflammatory activities. The hexanic fraction HF 11-14b was the most interesting fraction with antimicrobial, and anti-inflammatory activities. The benefit of L. racemosa as a traditional medicinal plant was confirmed as shown by its antibacterial, antifungal and anti-inflammatory activities. To the best of our knowledge, this is the first study reporting the biological activities of L. racemosa, including antiparasitic and anti-inflammatory activities.

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Section: Methodsmentioning

confidence: 99%

Antimicrobial, Antiparasitic, Anti‐Inflammatory, and Cytotoxic Activities of Lopezia racemosa

Cruz-Paredes

Balbás

Gómez‐Velasco

et al. 2013

The Scientific World Journal

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“…Antibacterial, antifungal and antiparasitic activities of extracts of Mexican medicinal plant Laennecia confusa of Asteraceae family were confirmed. Extracts including cyanogenic and cardiotonic glycosides demonstrated antibacterial activity against Staphylococcus aureus and antiparasitic activity against Leishmania donovani and were also found to be cytotoxic to macrophages(Martinez Ruiz et al, 2012).…”

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confidence: 99%

Cyanogenic Glycosides - Their Role and Potential in Plant Food Resources

Harenčár

Ražná²,

Nôžková

2021

J microb biotech food sci

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Plants have metabolites and mechanisms that provide them with the basic building blocks for germination, growth, and reproduction processes, while providing them with protection and increasing their adaptation to environmental stresses. Due to their multifunctional significance, cyanogenic glycosides (CNG) indicate the importance of their role in the plant organism. Their diversity and biochemical origin are worth noting. Paradoxically, several nutritionally important food sources of plant origin are characterized by the presence of cyanogenic glycosides in various tissues. Processing approaches of plant food resources ensure a reduction in the content of these ingredients to an acceptable safe level. Different bacteria-based biotechnological processes are applied to minimize the content of CNG in food products. For the usability and identification of the added value of plant food resources, it is important to know the functions and importance of antinutritional components of metabolism with a consequent impact on nutrition and health. In the review we provided a comprehensive view of the importance and potential of CNG in plants with a focus on food sources, where the model object was presented by linseed.

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“…The genus Conyza(Asteraceae) is comprised of approximately 400 species and several species are known for their use in traditional medicine. 39 Many ethnobotanical studies have documented the use of C. bonariensis in the ethnomedicines of different cultures. [40][41][42][43][44] Previous studies have confirmed bioactive properties for specific Conyza species.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial Screening of Medicinal Plants Popularly used in Mato Grosso for Treating Infections: Advances on the Evaluation of Conyza bonariensis (L.) Cronquist in vitro and in vivo Antibacterial Activities

Paula¹,

Martins²,

Arunachalam³

et al. 2018

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infections and resistance to antifungal agents have increased significantly in immunocompromised patients and these infections are responsible for a high rate of morbidity/mortality in severe cases. 1,4 The growing need for more effective and safe antimicrobial agents has led to the renewal of multidisciplinary investigation on natural products, where new approaches combined with traditional techniques, are accelerating tracking of substances, which present antimicrobial activities. In addition, it has also allowed identification of the molecular targets responsible for their effects, moreover, many of these substances present new mechanisms of action. 4 Medicinal plants constitute an arsenal of chemicals

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Antimicrobial, Anti-Inflammatory, Antiparasitic, and Cytotoxic Activities ofLaennecia confusa

Cited by 12 publications

References 20 publications

Antimicrobial, Antiparasitic, Anti‐Inflammatory, and Cytotoxic Activities of Lopezia racemosa

Antimicrobial, Antiparasitic, Anti‐Inflammatory, and Cytotoxic Activities of Lopezia racemosa

Cyanogenic Glycosides - Their Role and Potential in Plant Food Resources

Antimicrobial Screening of Medicinal Plants Popularly used in Mato Grosso for Treating Infections: Advances on the Evaluation of Conyza bonariensis (L.) Cronquist in vitro and in vivo Antibacterial Activities

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