Antimicrobial, anti-inflammatory and mutagenic investigation of the South African tree aloe (Aloe barberae)

Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria

“…The natural phytochemicals isolated from medicinal plants used in traditional medicine have been considered useful alternatives to synthetic drugs. Many medicinal plants and their products are widely used for prevention and treatment of oral infections (6)(7)(8)(9)(10)(11)(12)(13)(14)(15), and among them Aloe vera is of particular interest and has been used therapeutically for a long time (16)(17)(18)(19)(20). Using the agar diffusion method, Pandy and Mishra demonstrated that an ethanolic extract of Aloe vera leaves produced a wider zone of growth inhibition (29-30 mm) than the aqueous extract (3-4 mm) against Enterococcus bovis and Staphylococcus aureus.…”

“…The levels of these compounds in Aloe plants are highly variable according to species and strain, as well as growth conditions. The pharmacological actions of Aloe vera gel as studied in vitro and in vivo include anti-inflammatory, antibacterial, antioxidant, immune-boosting and hypoglycemic properties (16)(17)(18)(19)(20).…”

Effect of Aloe vera, chlorine dioxide, and chlorhexidine mouth rinses on plaque and gingivitis: A randomized controlled trial

“…Various in vitro and in vivo studies reported the pharmacological actions of Aloe vera gel, viz., anti-inflammatory, antibacterial, antiulcer, and antioxidant. [17][18][19][20] Considering the beneficial effects along with ease of availability, low cost, and no known adverse effects, Aloe vera could be a suitable alternative for prolonged use as plaque control agent. Recently, a mouth rinse containing chlorine dioxide (ClO 2 ) has become commercially available in the market (Freshclor, Group Pharmaceuticals Ltd, Bangalore, India).…”

The Plaque Inhibitory Effect of Aloe Vera Mouthrinse in A Four Day De Novo Plaque Formation Model- A Randomized, Double Blind Crossover Study

“…Various uses of Aloe vera in dentistry can be found in literature owing to its multiple properties like anti-inflammatory, antibacterial, antiviral, pain relieving, wound healing, moisturizing and antioxidant potential . [4][5][6] On the basis of these researches, the aim of the present study was to evaluate the plaque inhibitory efficacy of Aloe vera mouthrinse in a four day de novo plaque accumulation model by a crossover study design and to compare it with benchmark antiplaque agent chlorhexidine.…”