Antimicrobial and Antioxidative Activities in the Stem Extracts of Derris trifoliata, a Mangrove Shrub

Simlai, Aritra; Gangwar, Anjali; Ghonge, Sarthaki Avinash; Roy, Amit

doi:10.9734/jpri/2017/34455

Cited by 17 publications

(26 citation statements)

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“…[1][2][3] They are rich sources of alkaloids, saponins, tannins, flavonoids, terpenoids, and glycosides 1,4 many of which exhibit various bioactivities including anticancer, 5 antifungal, 2,3,6 antiviral, 4 antioxidant 7-9 and antibacterial activities. 2,4,6,8,10,11 The application of antibacterial compounds from coastal plants and sponges are not only limited in medication of disease caused by human pathogenic bacteria 12,13 but also have been applied to overcome the problem of fish bacterial infections. 2,12 Fish infection by pathogenic bacteria would cause a serious economic loss in aquaculture as it causes a negative impact either on the growth and survival rates of fishes.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Coastal Plants and Marine Sponges from Kei Island Indonesia against Bacterial Fish Pathogens

Hamdillah¹,

Isnansetyo²,

Istiqomah³

et al. 2019

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Southeast Maluku Regency, Maluku. Freshlycollected specimen of sponges and part of coastal plants including barks, leaves, fruits, and twigs were immediately transported to the laboratory. A total of 32 samples were washed with water to remove ABSTRACT Objective: The objective of this study was to investigate the antibacterial activity of coastal plants and marine sponges extracts against fish bacterial pathogens. Methods: Samples were extracted by maceration and the extracts were examined for their antibacterial activities against Streptococcus sp. BJ0509, Staphylococcus aureus ATCC 6538, Aeromonas hydrophila BA03 and Vibrio parahaemolyticus 29S by means of paper disc diffusion method. Active extracts were partitioned and purified by column chromatography. The purified substance was tested for minimum inhibitory concentration (MIC) against seven bacterial fish pathogens namely Streptococcus sp., Vibrio parahaemolyticus, V. alginolyticus, V. harveyi, Photobacterium damselae, Aeromonas hydrophila and A. dhakensis. Results: The highest antibacterial activity against all bacteria used in the assay was demonstrated by OKA 6, a bark extract sample of a coastal plant, Diospyros maritima. It showed a diameter of inhibition zones against Streptococcus sp. BJ0509, S. aureus ATCC 6538, A. hydrophila BA03 and V. parahaemolyticus 29S of 19, 33, 18, and 18 mm, respectively. The column chromatography fraction of OKA 6 inhibited the growth of S. aureus ATCC 6538 with MIC of 3.125 µg/mL. The MIC of this fraction against seven bacterial fish pathogens ranged < 0.098 to 3.125 µg/mL. The antibacterial activity of partially purified substance obtained from column chromatography fractionation of OKA 6 was higher than those of oxytetracycline and kanamycin. Conclusions: This result indicates that antibacterial activity of the partially purified substance is potentially higher than those of the commercial antibiotics tested. It further indicates that OKA 6 extract from D. maritima can serve as a promising resource for the development of therapeutic agents against bacterial infections in aquaculture.

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Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Coastal Plants and Marine Sponges from Kei Island Indonesia against Bacterial Fish Pathogens

Hamdillah¹,

Isnansetyo²,

Istiqomah³

et al. 2019

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“…αtocopherol) and synthetic (e.g. butylated hydroxyanisole, butylated hydroxytoluene, tertbutyl hydroquinone and propyl gallate) are broadly used in the food industry to lengthen shelf life as they inhibit lipid oxidation [12]. However, the use of these synthetic antioxidants is increasingly getting restricted because of their toxicity and health risks [13].…”

Section: Introductionmentioning

confidence: 99%

“…However, the use of these synthetic antioxidants is increasingly getting restricted because of their toxicity and health risks [13]. Therefore, discovery of novel antioxidative of natural origin is the urgent need of the hour and plants can be a good source for the purpose [12]. Earlier research focused on methanolic bark extracts to illustrate the antioxidant activity of S. caseolaris.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Screening and Comparative Antioxidant Activities of Fractions Isolated from Sonneratia caseolaris (Linn.) Bark Extracts

Munira

Islam

et al. 2019

EJMP

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Aims:Our study was carried out to appraise the phytochemical screening and antioxidant potentials of Sonneratia caseolaris (Linn.) bark extracts. Study Design: For the purpose of this experiment the extracts were subjected for an in-vitro study. Place and Duration of Study:The study was carried out in August 2014 in the Department of Pharmacy, Southeast University, Dhaka, Bangladesh. Methodology: The various fractions of Sonneratia caseolaris (Linn.) barks as Ethanolic (ETF), ethyl acetate (EAF), chloroform(CLF) and pet ether (PTF) fractions-were obtained after extraction Munira et al.; EJMP, 28(4): 1-9, 2019; Article no.EJMP.50657 2 were subjected to preliminary phytochemical screening. The antioxidant capacity of these fractions were evaluated using 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging assay .Total antioxidant activity and total phenolic content of ETF, EAF, CLF and PTF extracts of S. caseolaris were determined. Results: The phytochemical screening showed the presence of flavonoid, steroid, tannin compounds in large amounts. In DPPH scavenging assay among the extracts, ethanolic fractions exhibited the highest radical scavenging activity with IC50 of 4.57 μg /ml .The highest phenolic content was found in EAF extracts (63.00 mg of GAE / g. of dried extract) followed by CLF (36.25 mg of GAE / g. of dried extract) and PTF (26.28 mg of GAE /g. of dried extract). The highest total antioxidant activity was also found in ETF fraction (185 GAE/g of dried sample followed by EAF fraction (99.00GAE/g of dried sample), PTF (84.00 GAE/g of dried sample) and Chloroform (49.00 GAE/g of dried sample). Conclusion: Our result demonstrates that all the extractives of S. caseolaris have appreciable antioxidant activities. But, further study is necessary to isolate the active compounds. Original Research Article

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“…In recent years, analytical methods have been further developed in various fields of toxicology, such as metabolite identification (Ali et al 2015;Huybrechts et al 2015;Godoy et al 2013), characterization of volatile organic compounds (Schubert et al 2015;Hutzler et al 2014), DNA-adducts (Hu et al 2015), inflammatory mediators (Patel et al 2015;Kim et al 2013), characterization of plant extracts (Khan et al 2014;Simlai et al 2014;Naghiloo et al 2012) and metabolomics (Fang and Gonzalez 2014;Beger et al 2015;Pink et al 2014). The relevant basic principles of high-resolution mass spectrometry are given by Pleil and Isaacs (2016).…”

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confidence: 99%

Highlight report: high-resolution mass spectrometry

Blaszkewicz

2016

Arch Toxicol

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Antimicrobial and Antioxidative Activities in the Stem Extracts of Derris trifoliata, a Mangrove Shrub

Cited by 17 publications

References 0 publications

Antibacterial Activity of Coastal Plants and Marine Sponges from Kei Island Indonesia against Bacterial Fish Pathogens

Antibacterial Activity of Coastal Plants and Marine Sponges from Kei Island Indonesia against Bacterial Fish Pathogens

Phytochemical Screening and Comparative Antioxidant Activities of Fractions Isolated from Sonneratia caseolaris (Linn.) Bark Extracts

Highlight report: high-resolution mass spectrometry

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