Antimicrobial and antihemolytic properties of a CNF/AgNP-chitosan film: A potential wound dressing material

Hasibuan, Poppy Anjelisa Zaitun; Yuandani, Yuandani; Tanjung, Masitta; Gea, Saharman; Pasaribu, Khatarina Meldawati; Harahap, Mahyuni; Perangin-Angin, Yurika Almanda; Prayoga, Andre; Ginting, Junius Gian

doi:10.1016/j.heliyon.2021.e08197

Cited by 20 publications

(7 citation statements)

References 42 publications

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“…The enhancement of the antioxidant activity of AP-CSLNs originated from the combination of two effects: the inherent antioxidant properties of AP itself and the enhanced delivery provided by the nanocarriers [ 39 ]. Sharma et al (2019) detected higher antioxidant activity in curcumin-loaded NPs compared to free drugs [ 40 ].…”

Section: Resultsmentioning

confidence: 99%

Optimization of cationic nanoparticles stabilized by poloxamer 188: A potential approach for improving the biological activity of Aloe perryi

Aldayel,

Badran,

Alomrani

et al. 2023

Heliyon

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Section: Resultsmentioning

confidence: 99%

Optimization of cationic nanoparticles stabilized by poloxamer 188: A potential approach for improving the biological activity of Aloe perryi

Aldayel,

Badran,

Alomrani

et al. 2023

Heliyon

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“…The absorption peak at 1060 cm −1 was associated with the stretching vibration of the C-O-C bond on the pyran ring. The absorption peak at 897 cm −1 was attributed to the stretching vibration of the β-1, 4-glycosidic bond between cellulose molecules and the deformation vibration of O-H in the hydroxyl group of the sample that absorbed water molecules [ 32 , 33 ]. As for CUR, the broad absorption band at 3504 cm −1 represented a representative peak of the phenolic OH group’s stretching vibration.…”

Section: Resultsmentioning

confidence: 99%

Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies

Chang,

Wang,

Huang

et al. 2023

Foods

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Given its high biological and pharmacological activities, curcumin (CUR) offers promising applications in functional foods. However, its low stability and bioavailability have greatly hindered its application in the food industry. The present study prepared cellulose nanofiber (CNF) from bamboo shoot processing byproducts and investigated its potential as a low-cost carrier. Our results showed that CUR was immobilized on CNF surfaces mainly through hydrogen bonding and eventually encapsulated in CNF matrices, forming a CNF–CUR complex with an encapsulation efficiency of 88.34% and a loading capacity of 67.95%. The CUR encapsulated in the complex showed improved stability after thermal and UV light treatments. Moreover, a slow and extended release pattern of CUR in a simulated gastrointestinal tract was observed, which could be appropriately described using the Korsmeyer–Peppas model. These results revealed that CNF is a promising protective carrier for the slow release of CUR, making it a better candidate for functional foods.

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“…Hasibuan et al synthesized chitosan/cellulose composite films incorporated with AgNPs. The in vitro experiments revealed that the films containing nanoparticles induced the strongest inhibition zone when cultured with B. subtilis and P. aeruginosa , revealing excellent antibacterial activity suitable for bacterial-infected wound care [ 132 ].…”

Section: Chitosan-based Scaffolds Incorporated With Silver Nanoparticlesmentioning

confidence: 99%

Chitosan-Based Scaffolds Incorporated with Silver Nanoparticles for the Treatment of Infected Wounds

Alven,

Aderibigbe

2024

Pharmaceutics

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Bacterial infections are major problems in wound care due to their impact on the retarded process of wound healing, leading to chronic wounds. Most of the presently utilized wound dressing products exhibit poor antimicrobial properties. Wound dressings formulated from chitosan have been reported to be effective for treating infected wounds, resulting from the antibacterial properties of chitosan. The antibacterial properties of chitosan-based wound dressings can be further enhanced by incorporating metallic nanoparticles into them, such as silver, zinc, titanium, etc. The incorporation of silver nanoparticles into chitosan-based wound dressings has been widely explored in the design of antimicrobial wound dressings. The incorporation of silver nanoparticles into chitosan-based wound dressings promotes accelerated wound-healing processes due to enhanced antimicrobial activity. The accelerated wound healing by these metal-based nanoparticles is via the regulation of re-epithelialization and inflammation without affecting the viability of normal cells. However, there have been few reports that evaluate these wound dressings in infectious animal models to prove their efficacy. The in vivo toxicity of silver nanoparticles still needs to be addressed, revealing the need for further preclinical and clinical trials. The fabrication of wound dressings incorporated with silver nanoparticles has not been fully explored, especially for wounds requiring immediate treatment. The possible interactions between silver nanoparticles and chitosan scaffolds that result in synergistic effects still need to be understood and studied. This review provides a comprehensive report on the preclinical outcomes of chitosan wound dressing materials loaded with silver nanoparticles for managing infected wounds.

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Antimicrobial and antihemolytic properties of a CNF/AgNP-chitosan film: A potential wound dressing material

Cited by 20 publications

References 42 publications

Optimization of cationic nanoparticles stabilized by poloxamer 188: A potential approach for improving the biological activity of Aloe perryi

Optimization of cationic nanoparticles stabilized by poloxamer 188: A potential approach for improving the biological activity of Aloe perryi

Curcumin-Loaded Bamboo Shoot Cellulose Nanofibers: Characterization and In Vitro Studies

Chitosan-Based Scaffolds Incorporated with Silver Nanoparticles for the Treatment of Infected Wounds

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